Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with white-tailed deer ACE2
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 8hfx
Q-score: 0.46
Han P, Meng Y, Zhang D, Xu Z, Li Z, Pan X, Zhao Z, Li L, Tang L, Qi J, Liu K, Gao GF
J Virol (2023) 97 pp. e0050523-e0050523 [ DOI: doi:10.1128/jvi.00505-23 Pubmed: 37676003 ]
- Spike glycoprotein,envelope glycoprotein (139 kDa, Protein from Human immunodeficiency virus 1)
- Angiotensin-converting enzyme (71 kDa, Protein from Odocoileus virginianus texanus)
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 omicron ba.1 spike protein, envelope glycoprotein chimera in complex with white-tailed deer ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron BA.1 spike protein receptor-binding domain in complex with white-tailed deer ACE2
Resolution: 3.21 Å
EM Method: Single-particle
Fitted PDBs: 8hfy
Q-score: 0.506
Han P, Meng Y, Zhang D, Xu Z, Li Z, Pan X, Zhao Z, Li L, Tang L, Qi J, Liu K, Gao GF
J Virol (2023) 97 pp. e0050523-e0050523 [ DOI: doi:10.1128/jvi.00505-23 Pubmed: 37676003 ]
- Zinc ion (65 Da, Ligand)
- Sars-cov-2 omicron ba.1 spike protein receptor-binding domain in complex with white-tailed deer ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme (69 kDa, Protein from Odocoileus virginianus texanus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with white-tailed deer ACE2
Resolution: 2.71 Å
EM Method: Single-particle
Fitted PDBs: 8hfz
Q-score: 0.423
Han P, Meng Y, Zhang D, Xu Z, Li Z, Pan X, Zhao Z, Li L, Tang L, Qi J, Liu K, Gao GF
J Virol (2023) 97 pp. e0050523-e0050523 [ DOI: doi:10.1128/jvi.00505-23 Pubmed: 37676003 ]
- Angiotensin-converting enzyme (76 kDa, Protein from Odocoileus virginianus texanus)
- Zinc ion (65 Da, Ligand)
- Sars-cov-2 prototype spike protein in complex with white-tailed deer ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (135 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.51 Å
EM Method: Single-particle
Fitted PDBs: 8hg0
Q-score: 0.42
Han P, Meng Y, Zhang D, Xu Z, Li Z, Pan X, Zhao Z, Li L, Tang L, Qi J, Liu K, Gao GF
J Virol (2023) 97 pp. e0050523-e0050523 [ DOI: doi:10.1128/jvi.00505-23 Pubmed: 37676003 ]
- Angiotensin-converting enzyme (71 kDa, Protein from Odocoileus virginianus texanus)
- Zinc ion (65 Da, Ligand)
- Sars-cov-2 prototype spike protein receptor-binding domain in complex with white-tailed deer ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 spike protein in complex with white-tailed deer ACE2
Resolution: 2.55 Å
EM Method: Single-particle
Fitted PDBs: 8ify
Q-score: 0.382
Han P, Meng Y, Zhang D, Xu Z, Li Z, Pan X, Zhao Z, Li L, Tang L, Qi J, Liu K, Gao GF
J Virol (2023) 97 pp. e0050523-e0050523 [ DOI: doi:10.1128/jvi.00505-23 Pubmed: 37676003 ]
- Spike glycoprotein (125 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Angiotensin-converting enzyme (76 kDa, Protein from Odocoileus virginianus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of sars-cov-2 omicron ba.4/5 spike protein in complex with white-tailed deer ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8ifz
Q-score: 0.447
Han P, Meng Y, Zhang D, Xu Z, Li Z, Pan X, Zhao Z, Li L, Tang L, Qi J, Liu K, Gao GF
J Virol (2023) 97 pp. e0050523-e0050523 [ DOI: doi:10.1128/jvi.00505-23 Pubmed: 37676003 ]
- Sars-cov-2 omicron ba.4/5 spike protein receptor-binding domain in complex with white-tailed deer ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Angiotensin-converting enzyme (76 kDa, Protein from Odocoileus virginianus)
- Spike protein s1 (26 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 1 YB9-258 Fab (1 RBD up)
Resolution: 6.21 Å
EM Method: Single-particle
Fitted PDBs: 8hc2
Q-score: 0.154
Yu H, Liu B, Zhang Y, Gao X, Wang Q, Xiang H, Peng X, Xie C, Wang Y, Hu P, Shi J, Shi Q, Zheng P, Feng C, Tang G, Liu X, Guo L, Lin X, Li J, Liu C, Huang Y, Yang N, Chen Q, Li Z, Su M, Yan Q, Pei R, Chen X, Liu L, Hu F, Liang D, Ke B, Ke C, Li F, He J, Wang M, Chen L, Xiong X, Tang X
Nat Commun (2023) 14 pp. 1058-1058 [ DOI: doi:10.1038/s41467-023-36761-0 Pubmed: 36828833 ]
- Light chain of yb9-258 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of yb9-258 fab (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron ba.1 spike trimer with one rbd up in complex with one yb9-258 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (138 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Yb9-258 fab (Complex from Homo sapiens)
- Sars-cov-2 omicron ba.1 spike trimer (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 2 YB9-258 Fabs (2 RBD up)
Resolution: 4.35 Å
EM Method: Single-particle
Fitted PDBs: 8hc3
Q-score: 0.224
Yu H, Liu B, Zhang Y, Gao X, Wang Q, Xiang H, Peng X, Xie C, Wang Y, Hu P, Shi J, Shi Q, Zheng P, Feng C, Tang G, Liu X, Guo L, Lin X, Li J, Liu C, Huang Y, Yang N, Chen Q, Li Z, Su M, Yan Q, Pei R, Chen X, Liu L, Hu F, Liang D, Ke B, Ke C, Li F, He J, Wang M, Chen L, Xiong X, Tang X
Nat Commun (2023) 14 pp. 1058-1058 [ DOI: doi:10.1038/s41467-023-36761-0 Pubmed: 36828833 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of yb9-258 (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron ba.1 spike trimer with two rbd up in complex with two yb9-258 fab (Complex)
- Spike glycoprotein (138 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Yb9-258 fab (Complex from Homo sapiens)
- Heavy chain of yb9-258 (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron ba.1 spike trimer (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 wildtype spike trimer (6P) in complex with 3 YB9-258 Fabs and 3 R1-32 Fabs (3 RBD up)
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8hc4
Q-score: 0.221
Yu H, Liu B, Zhang Y, Gao X, Wang Q, Xiang H, Peng X, Xie C, Wang Y, Hu P, Shi J, Shi Q, Zheng P, Feng C, Tang G, Liu X, Guo L, Lin X, Li J, Liu C, Huang Y, Yang N, Chen Q, Li Z, Su M, Yan Q, Pei R, Chen X, Liu L, Hu F, Liang D, Ke B, Ke C, Li F, He J, Wang M, Chen L, Xiong X, Tang X
Nat Commun (2023) 14 pp. 1058-1058 [ DOI: doi:10.1038/s41467-023-36761-0 Pubmed: 36828833 ]
- Light chain of yb9-258 fab (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 wildtype spike trimer with three rbd up in complex with three yb9-258 fab and three r1-32 fab (Complex)
- Yb9-258 fab and r1-32 fab (Complex from Homo sapiens)
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of yb9-258 (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
- Sars-cov-2 wildtype spike trimer (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 3 YB13-292 Fabs (3 RBD down)
Resolution: 6.03 Å
EM Method: Single-particle
Fitted PDBs: 8hc9
Q-score: 0.156
Yu H, Liu B, Zhang Y, Gao X, Wang Q, Xiang H, Peng X, Xie C, Wang Y, Hu P, Shi J, Shi Q, Zheng P, Feng C, Tang G, Liu X, Guo L, Lin X, Li J, Liu C, Huang Y, Yang N, Chen Q, Li Z, Su M, Yan Q, Pei R, Chen X, Liu L, Hu F, Liang D, Ke B, Ke C, Li F, He J, Wang M, Chen L, Xiong X, Tang X
Nat Commun (2023) 14 pp. 1058-1058 [ DOI: doi:10.1038/s41467-023-36761-0 Pubmed: 36828833 ]
- Yb13-292 fab (Complex from Homo sapiens)
- Spike glycoprotein (138 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Light chain of yb13-292 fab (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron ba.1 spike trimer with three rbd down in complex with three yb13-292 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of yb13-292 fab (25 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron ba.1 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)