SARS-CoV-2 spike trimer (6P) in complex with three R1-26 Fabs
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- Sars-cov-2 spike trimer (6p) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- R1-26 fab (Complex from Homo sapiens)
- Sars-cov-2 spike trimer (6p) in complex with three r1-26 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 spike trimer (6P) in complex with R1-26 Fab, focused refinement of RBD-Fab region
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- Light chain of r1-26 fab (13 kDa, Protein from Homo sapiens)
- Heavy chain of r1-26 fab (15 kDa, Protein from Homo sapiens)
- R1-26 fab (Complex from Homo sapiens)
- Sars-cov-2 spike trimer (6p) in complex with three r1-26 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 spike trimer (6P) in complex with two H18 and two R1-32 Fabs
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- H18 fab (Complex from Homo sapiens)
- R1-32 fab (Complex from Homo sapiens)
- Sars-cov-2 spike trimer (6p) in complex with two h18 and two r1-32 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of h18 fab (25 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike trimer (6p) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of h18 fab (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
SARS-CoV-2 spike trimer (6P) in complex with three H18 and three R1-32 Fabs
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- H18 fab (Complex from Homo sapiens)
- Sars-cov-2 spike trimer (6p) in complex with three h18 and three r1-32 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- R1-32 fab (Complex from Homo sapiens)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of h18 fab (25 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike trimer (6p) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of h18 fab (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
SARS-CoV-2 S1 in complex with H18 and R1-32 Fab
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- H18 fab (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (74 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 s1 in complex with h18 and r1-32 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- R1-32 fab (Complex from Homo sapiens)
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of h18 fab (25 kDa, Protein from Homo sapiens)
- Light chain of h18 fab (25 kDa, Protein from Homo sapiens)
- Sars-cov-2 s1 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
Dimer of SARS-CoV-2 S1 in complex with H18 and R1-32 Fabs
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- H18 fab (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (74 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- R1-32 fab (Complex from Homo sapiens)
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of h18 fab (25 kDa, Protein from Homo sapiens)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
- Light chain of h18 fab (25 kDa, Protein from Homo sapiens)
- Dimer of sars-cov-2 s1 in complex with h18 and r1-32 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 s1 (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron BA.1 spike trimer (x2-4P) in complex with 3 D1F6 Fabs (0 RBD up)
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 8zby
Q-score: 0.372
Liu B, Niu X, Deng Y, Zhang Z, Wang Y, Gao X, Liang H, Li Z, Wang Q, Cheng Y, Chen Q, Huang S, Pan Y, Su M, Lin X, Niu C, Chen Y, Yang W, Zhang Y, Yan Q, He J, Zhao J, Chen L, Xiong X
Cell Rep (2024) 43 pp. 114265-114265 [ DOI: doi:10.1016/j.celrep.2024.114265 Pubmed: 38805396 ]
- Light chain of d1f6 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of d1f6 fab (24 kDa, Protein from Homo sapiens)
- Spike glycoprotein (138 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 omicron ba.1 spike trimer (x2-4p) in complex with 3 d1f6 fabs (0 rbd up) (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron BA.4 spike trimer (6P) in complex with 3 D1F6 Fabs (2 RBD up)
Resolution: 3.95 Å
EM Method: Single-particle
Fitted PDBs: 8zc4
Q-score: 0.372
Liu B, Niu X, Deng Y, Zhang Z, Wang Y, Gao X, Liang H, Li Z, Wang Q, Cheng Y, Chen Q, Huang S, Pan Y, Su M, Lin X, Niu C, Chen Y, Yang W, Zhang Y, Yan Q, He J, Zhao J, Chen L, Xiong X
Cell Rep (2024) 43 pp. 114265-114265 [ DOI: doi:10.1016/j.celrep.2024.114265 Pubmed: 38805396 ]
- Light chain of d1f6 fab (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron ba.4 spike trimer (6p) in complex with 3 d1f6 fabs (2 rbd up) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of d1f6 fab (24 kDa, Protein from Homo sapiens)
- Spike glycoprotein (137 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 Omicron BA.4 spike trimer (6P) in complex with D1F6 Fab, focused refinement of RBD region
Resolution: 3.91 Å
EM Method: Single-particle
Fitted PDBs: 8zc5
Q-score: 0.439
Liu B, Niu X, Deng Y, Zhang Z, Wang Y, Gao X, Liang H, Li Z, Wang Q, Cheng Y, Chen Q, Huang S, Pan Y, Su M, Lin X, Niu C, Chen Y, Yang W, Zhang Y, Yan Q, He J, Zhao J, Chen L, Xiong X
Cell Rep (2024) 43 pp. 114265-114265 [ DOI: doi:10.1016/j.celrep.2024.114265 Pubmed: 38805396 ]
- Light chain of d1f6 fab (11 kDa, Protein from Homo sapiens)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of d1f6 fab (14 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron ba.4 spike trimer (6p) in complex with d1f6 fab, focused refinement of rbd region (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 Omicron BA.1 spike protein receptor-binding domain in complex with white-tailed deer ACE2
Resolution: 3.21 Å
EM Method: Single-particle
Fitted PDBs: 8hfy
Q-score: 0.506
Han P, Meng Y, Zhang D, Xu Z, Li Z, Pan X, Zhao Z, Li L, Tang L, Qi J, Liu K, Gao GF
J Virol (2023) 97 pp. e0050523-e0050523 [ DOI: doi:10.1128/jvi.00505-23 Pubmed: 37676003 ]
- Zinc ion (65 Da, Ligand)
- Sars-cov-2 omicron ba.1 spike protein receptor-binding domain in complex with white-tailed deer ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme (69 kDa, Protein from Odocoileus virginianus texanus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)