Cryo-EM Structure of MILI(K852A)-piRNA-target (26-nt)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9ij4
Q-score: 0.474
Li Z, Xu Q, Zhong J, Zhang Y, Zhang T, Ying X, Lu X, Li X, Wan L, Xue J, Huang J, Zhen Y, Zhang Z, Wu J, Shen EZ
Nature (2025) [ Pubmed: 39814893 DOI: doi:10.1038/s41586-024-08438-1 ]
- Mili(k852a)-pirna-target (26-nt) (Complex from Homo sapiens)
- Rna (26-mer) (8 kDa, RNA from Homo sapiens)
- Piwi-like protein 2 (109 kDa, Protein from Mus musculus)
- Magnesium ion (24 Da, Ligand)
- Rna (25-mer) (8 kDa, RNA from Homo sapiens)
Resolution: 3.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 9ikm
Q-score: 0.422
Cryo-EM structure of Lactobacillus casei DdmE bound with guide and target
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 9iw3
Q-score: 0.438
Huang P, Yan P, Guo L, Fei W, Li Z, Liu J, Kong J, Yao Y, Lu M, Xiao Y, Chen M
Cell Res (2024) 34 pp. 873-876 [ DOI: doi:10.1038/s41422-024-01042-y Pubmed: 39448873 ]
- Dna (25-mer) (7 kDa, DNA from Lacticaseibacillus)
- Lactobacillus casei ddme bound with guide and target (Complex from Lacticaseibacillus)
- Ddme (83 kDa, Protein from Lacticaseibacillus)
- Dna (5'-d(p*cp*tp*tp*gp*ap*tp*ap*cp*gp*ap*c)-3') (3 kDa, DNA from Lacticaseibacillus)
- Dna (5'-d(p*tp*gp*ap*cp*gp*gp*cp*tp*cp*tp*ap*ap*tp*cp*t)-3') (4 kDa, DNA from Lacticaseibacillus)
- Magnesium ion (24 Da, Ligand)
Cryo-EM structure of Lactobacillus casei DdmD dimer bound with DNA
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 9ix4
Q-score: 0.483
Huang P, Yan P, Guo L, Fei W, Li Z, Liu J, Kong J, Yao Y, Lu M, Xiao Y, Chen M
Cell Res (2024) 34 pp. 873-876 [ DOI: doi:10.1038/s41422-024-01042-y Pubmed: 39448873 ]
- Ddmd (137 kDa, Protein from Lacticaseibacillus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dna (5'-d(p*ap*ap*ap*ap*ap*ap*ap*ap*ap*a)-3') (3 kDa, DNA from Lacticaseibacillus)
- Dna (5'-d(p*tp*ap*tp*gp*ap*gp*tp*ap*tp*ap*tp*cp*c)-3') (3 kDa, DNA from Lacticaseibacillus)
- Lactobacillus casei ddmd bound with dna substrate (Complex from Lacticaseibacillus)
- Dna (5'-d(p*ap*tp*gp*ap*gp*tp*ap*tp*ap*tp*cp*c)-3') (3 kDa, DNA from Lacticaseibacillus)
Cryo-EM structure of Lactobacillus casei DdmDE bound with DNA
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 9ixm
Q-score: 0.464
Huang P, Yan P, Guo L, Fei W, Li Z, Liu J, Kong J, Yao Y, Lu M, Xiao Y, Chen M
Cell Res (2024) 34 pp. 873-876 [ DOI: doi:10.1038/s41422-024-01042-y Pubmed: 39448873 ]
- Ddmd (137 kDa, Protein from Lacticaseibacillus)
- Dna (30-mer) (9 kDa, DNA from Lacticaseibacillus)
- Ddme (83 kDa, Protein from Lacticaseibacillus)
- Magnesium ion (24 Da, Ligand)
- Dna (5'-d(p*tp*gp*ap*cp*gp*gp*cp*tp*cp*tp*ap*ap*tp*cp*t)-3') (4 kDa, DNA from Lacticaseibacillus)
- Lactobacillus casei ddmde bound with dna (Complex from Lacticaseibacillus)
- Dna (30-mer) (9 kDa, DNA from Lacticaseibacillus)