SARS-CoV-2 Spike in complex with Fab of m31A7
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7wuh
Q-score: 0.245
Huang HY, Liao HY, Chen X, Wang SW, Cheng CW, Shahed-Al-Mahmud M, Liu YM, Mohapatra A, Chen TH, Lo JM, Wu YM, Ma HH, Chang YH, Tsai HY, Chou YC, Hsueh YP, Tsai CY, Huang PY, Chang SY, Chao TL, Kao HC, Tsai YM, Chen YH, Wu CY, Jan JT, Cheng TR, Lin KI, Ma C, Wong CH
Sci Transl Med (2022) 14 pp. eabm0899-eabm0899 [ Pubmed: 35230146 DOI: doi:10.1126/scitranslmed.abm0899 ]
- Sars-cov2 spike (Complex from Homo sapiens)
- M31a7 fab heavy chain (25 kDa, Protein from Homo sapiens)
- M31a7 (Complex)
- Spike glycoprotein (137 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- M31a7 fab light chain (26 kDa, Protein from Homo sapiens)
- Sars-cov2 spike in complex with m31a7 (560 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Negative stain volume of the mono-GlcNAc-decorated SARS-CoV-2 Spike
Huang HY, Liao HY, Chen X, Wang SW, Cheng CW, Shahed-Al-Mahmud M, Liu YM, Mohapatra A, Chen TH, Lo JM, Wu YM, Ma HH, Chang YH, Tsai HY, Chou YC, Hsueh YP, Tsai CY, Huang PY, Chang SY, Chao TL, Kao HC, Tsai YM, Chen YH, Wu CY, Jan JT, Cheng TR, Lin KI, Ma C, Wong CH
Sci Transl Med (2022) 14 pp. eabm0899-eabm0899 [ Pubmed: 35230146 DOI: doi:10.1126/scitranslmed.abm0899 ]
- Sars-cov-2 spike (430 MDa, Complex from Severe acute respiratory syndrome coronavirus 2)
Ribosome conformation along minimum free-energy trajectory
Dashti A, Schwander P, Langlois R, Fung R, Li W, Hosseinizadeh A, Liao HY, Pallesen J, Sharma G, Stupina VA, Simon AE, Dinman J, Frank J, Ourmazd A
PNAS (2014) 111 pp. 17492-17497 [ Pubmed: 25422471 DOI: doi:10.1073/pnas.1419276111 ]
Cryo-EM map of the CSFV IRES in complex with the small ribosomal 40S subunit and DHX29
Resolution: 8.5 Å
EM Method: Single-particle
Fitted PDBs: 4c4q
Q-score: 0.126
Hashem Y, des Georges A, Dhote A, Langlois R, Liao HY, Grassucci RA, Pestova TV, Hellen CUT, Frank J
Nature (2013) 503 pp. 539-543 [ Pubmed: 24185006 DOI: doi:10.1038/nature12658 ]
- Csfv ires truncated from domain ii, in complex with the rabbit small ribosomal 40s subunit and to dhx29 (1 MDa, Sample)
- Dhx29 (150 kDa, Protein from Homo sapiens)
- Internal ribosomal entry site (100 kDa, RNA from Classical swine fever virus)
- Eukaryotic small ribosmal subunit (1 MDa, Complex from Oryctolagus cuniculus)
Cryo-EM structure of the CSFV IRES in complex with eIF3, small ribosomal 40S subunit and DHX29
Hashem Y, des Georges A, Dhote V, Langlois R, Liao HY, Grassucci RA, Pestova TV, Hellen CU, Frank J
Nature (2013) 503 pp. 539-543 [ Pubmed: 24185006 DOI: doi:10.1038/nature12658 ]
- Eukaryotic small ribosmal subunit (1 MDa, Complex from Oryctolagus cuniculus)
- Dhx29 (150 kDa, Protein from Homo sapiens)
- Reconstruction of a mutant classical swine fever virus ires bound to eukaryotic initiation factor 3, the rabbit 40s subunit and dhx29. (2 MDa, Sample)
- Internal ribosomal entry site (100 kDa, RNA from Classical swine fever virus)
- Eukaryotic initiation factor 3 (850 kDa, Protein from Oryctolagus cuniculus)
Cryo-electron microscopy structure of the mammalian 43S preinitiation complex bound to DHX29
Hashem Y, des Georges A, Dhote V, Langlois R, Liao HY, Grassucci RA, Hellen CU, Pestova TV, Frank J
Cell (2013) 153 pp. 1108-1119 [ Pubmed: 23706745 DOI: doi:10.1016/j.cell.2013.04.036 ]
- Transfer rna (25 kDa, RNA from Oryctolagus cuniculus)
- Eukaryotic initiation factor 1 (14 kDa, Protein from Oryctolagus cuniculus)
- Dhx29 (150 kDa, Protein from Oryctolagus cuniculus)
- Eukaryotic small ribosomal subunit (1 MDa, Complex from Oryctolagus cuniculus)
- Eukaryotic initiation factor 2 (150 kDa, Protein from Oryctolagus cuniculus)
- Eukaryotic initiation factor 1a (19 kDa, Protein from Oryctolagus cuniculus)
- Cryo-electron microscopy structure of the mammalian 43s preinitiation complex bound to dhx29 (Sample)
- Eukaryotic initiation factor 3 (800 kDa, Protein from Oryctolagus cuniculus)
Cryo-electron microscopy structure of the Trypanosoma brucei 80S ribosome
Resolution: 5.57 Å
EM Method: Single-particle
Fitted PDBs: 4v8m
Q-score: 0.239
Hashem Y, des Georges A, Fu J, Buss SN, Jossinet F, Jobe A, Zhang Q, Liao HY, Grassucci RA, Bajaj C, Westhof E, Madison-Antenucci S, Frank J
Nature (2013) 494 pp. 385-389 [ Pubmed: 23395961 DOI: doi:10.1038/nature11872 ]
- 80s ribosome (3 MDa, Complex from Trypanosoma brucei)
- Trypanosoma brucei 80s ribosome (3 MDa, Sample)
Resolution: 14.7 Å
EM Method: Single-particle
Fitted PDBs: 4v6o
Q-score: 0.065
Agirrezabala X, Liao HY, Schreiner E, Fu J, Ortiz-Meoz RF, Schulten K, Green R, Frank J
PNAS (2012) 109 pp. 6094-6099 [ DOI: doi:10.1073/pnas.1201288109 Pubmed: 22467828 ]
- Trp-trna-eftu-gdp-kir-70s ribosome (2 MDa, Sample)
- 70s ribosome (Complex from Escherichia coli)
Resolution: 13.1 Å
EM Method: Single-particle
Fitted PDBs: 4v6s
Q-score: 0.068
Agirrezabala X, Liao HY, Schreiner E, Fu J, Ortiz-Meoz RF, Schulten K, Green R, Frank J
PNAS (2012) 109 pp. 6094-6099 [ DOI: doi:10.1073/pnas.1201288109 Pubmed: 22467828 ]
- Trp-trna-eftu-gdp-kir-70s ribosome (2 MDa, Sample)
- 70s ribosome (Complex from Escherichia coli)
Resolution: 12.1 Å
EM Method: Single-particle
Fitted PDBs: 4v6n
Q-score: 0.077
Agirrezabala X, Liao HY, Schreiner E, Fu J, Ortiz-Meoz RF, Schulten K, Green R, Frank J
PNAS (2012) 109 pp. 6094-6099 [ DOI: doi:10.1073/pnas.1201288109 Pubmed: 22467828 ]
- Trp-trna-eftu-gdp-kir-70s ribosome (2 MDa, Sample)
- 70s ribosome (Complex from Escherichia coli)