Structure of human B-cell antigen receptor of the IgM isotype
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7xq8
Q-score: 0.313
Su Q, Chen M, Shi Y, Zhang X, Huang G, Huang B, Liu D, Liu Z, Shi Y
Science (2022) 377 pp. 875-880 [ DOI: doi:10.1126/science.abo3923 Pubmed: 35981043 ]
- Light chain (Complex from Homo sapiens)
- B-cell antigen receptor complex-associated protein alpha chain (28 kDa, Protein from Homo sapiens)
- Heavy chain (Complex from Homo sapiens)
- Human b-cell antigen receptor (Complex)
- Chimera of heavy chain of vrc01 antibody fab and isoform 2 of immunoglobulin heavy constant mu (67 kDa, Protein from Homo sapiens)
- Structure of human b-cell antigen receptor of the igm isotype (Complex from Homo sapiens)
- Light chain of fab fragments of the vrc01 antibody,immunoglobulin kappa constant (27 kDa, Protein from Homo sapiens)
- B-cell antigen receptor complex-associated protein beta chain (29 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of the fibril formed by disaccharide-modified amyloid-beta(1-42)
Cryo_EM structure of delta N-NPC1L1-CLR
Resolution: 2.69 Å
EM Method: Single-particle
Fitted PDBs: 7dfw
Q-score: 0.584
Hu M, Yang F, Huang Y, You X, Liu D, Sun S, Sui SF
Sci Adv (2021) 7 [ Pubmed: 34272236 DOI: doi:10.1126/sciadv.abg3188 ]
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Complex of delta n-npc1l1 with clr (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Npc1-like intracellular cholesterol transporter 1 (141 kDa, Protein from Homo sapiens)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo_EM structure of delta N-NPC1L1-EZE
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 7dfz
Q-score: 0.481
Hu M, Yang F, Huang Y, You X, Liu D, Sun S, Sui SF
Sci Adv (2021) 7 [ Pubmed: 34272236 DOI: doi:10.1126/sciadv.abg3188 ]
- Npc1-like intracellular cholesterol transporter 1 (139 kDa, Protein from Homo sapiens)
- (3~{r},4~{s})-1-(4-fluorophenyl)-3-[(3~{s})-3-(4-fluorophenyl)-3-oxidanyl-propyl]-4-(4-hydroxyphenyl)azetidin-2-one (409 Da, Ligand)
- Delta n-hnpc1l1-eze (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 7df8
Q-score: 0.54
Hu M, Yang F, Huang Y, You X, Liu D, Sun S, Sui SF
Sci Adv (2021) 7 [ Pubmed: 34272236 DOI: doi:10.1126/sciadv.abg3188 ]
- Full length npc1l1 (Cell from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Npc1-like intracellular cholesterol transporter 1 (139 kDa, Protein from Homo sapiens)
The cryo-EM structure of coxsackievirus A16 mature virion
Resolution: 3.56 Å
EM Method: Single-particle
Fitted PDBs: 6lha
Q-score: 0.504
He M, Xu L, Zheng Q, Zhu R, Yin Z, Zha Z, Lin Y, Yang L, Huang Y, Ye X, Li S, Hou W, Wu Y, Han J, Liu D, Li Z, Chen Z, Yu H, Que Y, Wang Y, Yan X, Zhang J, Gu Y, Zhou ZH, Cheng T, Li S, Xia N
Cell Host Microbe (2020) 27 pp. 249- [ Pubmed: 32027857 DOI: doi:10.1016/j.chom.2020.01.003 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Vp4 protein (7 kDa, Protein from Coxsackievirus A16)
- Sphingosine (299 Da, Ligand)
- Vp3 protein (26 kDa, Protein from Coxsackievirus A16)
- Vp2 protein (27 kDa, Protein from Coxsackievirus A16)
- Vp1 protein (33 kDa, Protein from Coxsackievirus A16)
The cryo-EM structure of coxsackievirus A16 A-particle
Resolution: 3.33 Å
EM Method: Single-particle
Fitted PDBs: 6lhb
Q-score: 0.528
He M, Xu L, Zheng Q, Zhu R, Yin Z, Zha Z, Lin Y, Yang L, Huang Y, Ye X, Li S, Hou W, Wu Y, Han J, Liu D, Li Z, Chen Z, Yu H, Que Y, Wang Y, Yan X, Zhang J, Gu Y, Zhou ZH, Cheng T, Li S, Xia N
Cell Host Microbe (2020) 27 pp. 249- [ Pubmed: 32027857 DOI: doi:10.1016/j.chom.2020.01.003 ]
- Vp2 (27 kDa, Protein from Coxsackievirus A16)
- Vp3 (26 kDa, Protein from Coxsackievirus A16)
- Vp1 (33 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
The cryo-EM structure of coxsackievirus A16 empty particle
Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 6lhc
Q-score: 0.517
He M, Xu L, Zheng Q, Zhu R, Yin Z, Zha Z, Lin Y, Yang L, Huang Y, Ye X, Li S, Hou W, Wu Y, Han J, Liu D, Li Z, Chen Z, Yu H, Que Y, Wang Y, Yan X, Zhang J, Gu Y, Zhou ZH, Cheng T, Li S, Xia N
Cell Host Microbe (2020) 27 pp. 249- [ Pubmed: 32027857 DOI: doi:10.1016/j.chom.2020.01.003 ]
- Vp2 (27 kDa, Protein from Coxsackievirus A16)
- Vp3 (26 kDa, Protein from Coxsackievirus A16)
- Vp1 (33 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
The cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab 18A7
Resolution: 2.65 Å
EM Method: Single-particle
Fitted PDBs: 6lhk
Q-score: 0.634
He M, Xu L, Zheng Q, Zhu R, Yin Z, Zha Z, Lin Y, Yang L, Huang Y, Ye X, Li S, Hou W, Wu Y, Han J, Liu D, Li Z, Chen Z, Yu H, Que Y, Wang Y, Yan X, Zhang J, Gu Y, Zhou ZH, Cheng T, Li S, Xia N
Cell Host Microbe (2020) 27 pp. 249- [ Pubmed: 32027857 DOI: doi:10.1016/j.chom.2020.01.003 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Vp4 protein (7 kDa, Protein from Coxsackievirus A16)
- Sphingosine (299 Da, Ligand)
- Vp3 protein (26 kDa, Protein from Coxsackievirus A16)
- Vp2 protein (27 kDa, Protein from Coxsackievirus A16)
- Vp1 protein (33 kDa, Protein from Coxsackievirus A16)