Cryo-EM structure of Stimulator of interferon genes
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8ik0
Q-score: 0.446
Structure of Stimulator of interferon genes/ligand complex
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8ik3
Q-score: 0.452
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7xlq
Q-score: 0.482
Gao Y, Xu S, Cui X, Xu H, Qiu Y, Wei Y, Dong Y, Zhu B, Peng C, Liu S, Zhang XC, Sun J, Huang Z, Zhao Y
Nat Commun (2023) 14 pp. 516-516 [ DOI: doi:10.1038/s41467-023-36260-2 Pubmed: 36720859 ]
- Hexadecane (226 Da, Ligand)
- Human r-type voltage-gated calcium channel cav2.3-alpha2/delta1-beta1 complex (Complex from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Voltage-dependent l-type calcium channel subunit beta-1 (65 kDa, Protein from Homo sapiens)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (122 kDa, Protein from Homo sapiens)
- Voltage-dependent r-type calcium channel subunit alpha-1e (262 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv282
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7we7
Q-score: 0.315
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- The light chain of fab 282 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Homo sapiens)
- Heavy chain of fab 282 (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab 282 (Complex from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv265
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7we8
Q-score: 0.363
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- Fab 265 (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of fab 265 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of fab 265 (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv289
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7we9
Q-score: 0.349
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Severe acute respiratory syndrome coronavirus 2)
- The light chain of fab xgv289 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab 289 (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The heavy chain of fab xgv289 (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7wea
Q-score: 0.421
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- The light chain of fab xgv347 (11 kDa, Protein from Homo sapiens)
- Fab xgv347 (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Severe acute respiratory syndrome coronavirus 2)
- The heavy chain of fab xgv347 (13 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron variant spike protein with two XGv347 binding to two open state RBDs
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7web
Q-score: 0.337
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- The light chain of fab xgv347 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Homo sapiens)
- The heavy chain of fab xgv347 (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab 347 (Complex from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron variant spike protein with three XGv347 Fabs binding to three closed state RBDs
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7wec
Q-score: 0.433
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- The light chain of fab xgv347 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Homo sapiens)
- The heavy chain of fab xgv347 (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab 347 (Complex from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv265
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7wee
Q-score: 0.415
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- Fab 265 (Complex)
- The light chain of fab xgv265 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron mutation spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- The heavy chain of fab xgv265 (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)