Cryo-EM structure of human SIDT1 protein with C1 symmetry at neutral pH
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8woq
Q-score: 0.501
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ DOI: doi:10.1038/s41421-024-00647-2 Pubmed: 38378654 ]
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Oleic acid (282 Da, Ligand)
- Ternary complex of sidt1 in complex with unknown lipids (Complex from Homo sapiens)
- Octanoic acid (2-hydroxy-1-hydroxymethyl-heptadec-3-enyl)-amide (425 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
Cryo-EM structure of human SIDT1 protein with C2 symmetry at neutral pH
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8wor
Q-score: 0.533
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ DOI: doi:10.1038/s41421-024-00647-2 Pubmed: 38378654 ]
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Oleic acid (282 Da, Ligand)
- Ternary complex of sidt1 in complex with unknown lipids (Complex from Homo sapiens)
- Octanoic acid (2-hydroxy-1-hydroxymethyl-heptadec-3-enyl)-amide (425 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
Cryo-EM structure of human SIDT1 protein with C1 symmetry at low pH
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 8wos
Q-score: 0.418
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ DOI: doi:10.1038/s41421-024-00647-2 Pubmed: 38378654 ]
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Human sidt1 at low ph (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
Cryo-EM structure of human SIDT1 protein with C2 symmetry at low pH
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8wot
Q-score: 0.458
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ DOI: doi:10.1038/s41421-024-00647-2 Pubmed: 38378654 ]
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Human sidt1 at low ph (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
Adenosine receptor bound to an agonist in complex with G protein obtained by cryo-EM
Resolution: 2.99 Å
EM Method: Single-particle
Fitted PDBs: 7xy6
Q-score: 0.468
Chen Y, Zhang J, Weng Y, Xu Y, Lu W, Liu W, Liu M, Hua T, Song G
Sci Adv (2022) 8 pp. eadd3709-eadd3709 [ Pubmed: 36563137 DOI: doi:10.1126/sciadv.add3709 ]
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- G protein (Complex from Oplophorus gracilirostris)
- 2-[6-azanyl-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylethanamide (379 Da, Ligand)
- Soluble cytochrome b562,adenosine receptor a2b,lgbit (69 kDa, Protein from Oplophorus gracilirostris)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Adenosine receptor bound to an agonist in complex with g protein obtained by cryo-em (Complex from Homo sapiens)
- Soluble cytochrome b562,adenosine receptor a2b,lgbit (Complex)
Adenosine receptor bound to a non-selective agonist in complex with a G protein obtained by cryo-EM
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 7xy7
Q-score: 0.443
Chen Y, Zhang J, Weng Y, Xu Y, Lu W, Liu W, Liu M, Hua T, Song G
Sci Adv (2022) 8 pp. eadd3709-eadd3709 [ Pubmed: 36563137 DOI: doi:10.1126/sciadv.add3709 ]
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,adenosine receptor a2b,lgbit (69 kDa, Protein from Oplophorus gracilirostris)
- N-ethyl-5'-carboxamido adenosine (308 Da, Ligand)
- Adenosine receptor a2b bound to a non-selective agonist in complex with g protein obtained by cryo-em (Complex from Homo sapiens)
- G protein (Complex from Homo sapiens)
- Soluble cytochrome b562,adenosine receptor (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)