Cryo-EM structure of human SIDT1 protein with C1 symmetry at neutral pH
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8woq
Q-score: 0.501
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ Pubmed: 38378654 DOI: doi:10.1038/s41421-024-00647-2 ]
- Ternary complex of sidt1 in complex with unknown lipids (Complex from Homo sapiens)
- Oleic acid (282 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Octanoic acid (2-hydroxy-1-hydroxymethyl-heptadec-3-enyl)-amide (425 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Water (18 Da, Ligand)
Cryo-EM structure of human SIDT1 protein with C2 symmetry at neutral pH
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8wor
Q-score: 0.533
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ Pubmed: 38378654 DOI: doi:10.1038/s41421-024-00647-2 ]
- Ternary complex of sidt1 in complex with unknown lipids (Complex from Homo sapiens)
- Oleic acid (282 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Octanoic acid (2-hydroxy-1-hydroxymethyl-heptadec-3-enyl)-amide (425 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Water (18 Da, Ligand)
Cryo-EM structure of human SIDT1 protein with C1 symmetry at low pH
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 8wos
Q-score: 0.418
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ Pubmed: 38378654 DOI: doi:10.1038/s41421-024-00647-2 ]
- Cholesterol (386 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Human sidt1 at low ph (Complex from Homo sapiens)
Cryo-EM structure of human SIDT1 protein with C2 symmetry at low pH
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8wot
Q-score: 0.458
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ Pubmed: 38378654 DOI: doi:10.1038/s41421-024-00647-2 ]
- Cholesterol (386 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Human sidt1 at low ph (Complex from Homo sapiens)
Adenosine receptor bound to an agonist in complex with G protein obtained by cryo-EM
Resolution: 2.99 Å
EM Method: Single-particle
Fitted PDBs: 7xy6
Q-score: 0.468
Chen Y, Zhang J, Weng Y, Xu Y, Lu W, Liu W, Liu M, Hua T, Song G
Sci Adv (2022) 8 pp. eadd3709-eadd3709 [ DOI: doi:10.1126/sciadv.add3709 Pubmed: 36563137 ]
- Adenosine receptor bound to an agonist in complex with g protein obtained by cryo-em (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,adenosine receptor a2b,lgbit (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,adenosine receptor a2b,lgbit (69 kDa, Protein from Oplophorus gracilirostris)
- G protein (Complex from Oplophorus gracilirostris)
- 2-[6-azanyl-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylethanamide (379 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
Adenosine receptor bound to a non-selective agonist in complex with a G protein obtained by cryo-EM
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 7xy7
Q-score: 0.443
Chen Y, Zhang J, Weng Y, Xu Y, Lu W, Liu W, Liu M, Hua T, Song G
Sci Adv (2022) 8 pp. eadd3709-eadd3709 [ DOI: doi:10.1126/sciadv.add3709 Pubmed: 36563137 ]
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,adenosine receptor a2b,lgbit (69 kDa, Protein from Oplophorus gracilirostris)
- G protein (Complex from Homo sapiens)
- Soluble cytochrome b562,adenosine receptor (Complex)
- N-ethyl-5'-carboxamido adenosine (308 Da, Ligand)
- Adenosine receptor a2b bound to a non-selective agonist in complex with g protein obtained by cryo-em (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
Cryo-EM structure of human TMEM120A in the CoASH-bound state
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7f3t
Q-score: 0.443
Rong Y, Jiang J, Gao Y, Guo J, Song D, Liu W, Zhang M, Zhao Y, Xiao B, Liu Z
eLife (2021) 10 [ Pubmed: 34409941 DOI: doi:10.7554/eLife.71474 ]
- Coenzyme a (767 Da, Ligand)
- Transmembrane protein 120a (44 kDa, Protein from Homo sapiens)
- Transmembrane protein 120a (Cell from Homo sapiens)
Cryo-EM structure of human TMEM120A in the CoASH-free state
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7f3u
Q-score: 0.335
Rong Y, Jiang J, Gao Y, Guo J, Song D, Liu W, Zhang M, Zhao Y, Xiao B, Liu Z
eLife (2021) 10 [ Pubmed: 34409941 DOI: doi:10.7554/eLife.71474 ]
- Transmembrane protein 120a (44 kDa, Protein from Homo sapiens)
- Transmembrane protein 120a (Cell from Homo sapiens)
SARS-CoV-2 spike in complex with the CA521 neutralizing antibody Fab (focused refinement on Fab-RBD)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7e23
Q-score: 0.487
Song D, Wang W, Dong C, Ning Z, Liu X, Liu C, Du G, Sha C, Wang K, Lu J, Sun B, Zhao Y, Wang Q, Xu H, Li Y, Shen Z, Jiao J, Wang R, Tian J, Liu W, Wang L, Deng YQ, Dou C
Commun Biol (2021) 4 pp. 500-500 [ Pubmed: 33893388 DOI: doi:10.1038/s42003-021-02029-w ]
- Ca521 fab-rbd sub-complex (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ca521 heavy chain (49 kDa, Protein from Homo sapiens)
- Ca521 heavy chain (Complex from Homo sapiens)
- Ca521 light chain (Complex from Homo sapiens)
- Ca521 light chain (23 kDa, Protein from Homo sapiens)
- Spike protein s1 2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)