Adenosine receptor bound to an agonist in complex with G protein obtained by cryo-EM
Resolution: 2.99 Å
EM Method: Single-particle
Fitted PDBs: 7xy6
Q-score: 0.468
Chen Y, Zhang J, Weng Y, Xu Y, Lu W, Liu W, Liu M, Hua T, Song G
Sci Adv (2022) 8 pp. eadd3709-eadd3709 [ DOI: doi:10.1126/sciadv.add3709 Pubmed: 36563137 ]
- Soluble cytochrome b562,adenosine receptor a2b,lgbit (69 kDa, Protein from Oplophorus gracilirostris)
- 2-[6-azanyl-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylethanamide (379 Da, Ligand)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,adenosine receptor a2b,lgbit (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- G protein (Complex from Oplophorus gracilirostris)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Adenosine receptor bound to an agonist in complex with g protein obtained by cryo-em (Complex from Homo sapiens)
Adenosine receptor bound to a non-selective agonist in complex with a G protein obtained by cryo-EM
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 7xy7
Q-score: 0.443
Chen Y, Zhang J, Weng Y, Xu Y, Lu W, Liu W, Liu M, Hua T, Song G
Sci Adv (2022) 8 pp. eadd3709-eadd3709 [ DOI: doi:10.1126/sciadv.add3709 Pubmed: 36563137 ]
- Soluble cytochrome b562,adenosine receptor a2b,lgbit (69 kDa, Protein from Oplophorus gracilirostris)
- Adenosine receptor a2b bound to a non-selective agonist in complex with g protein obtained by cryo-em (Complex from Homo sapiens)
- G protein (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- N-ethyl-5'-carboxamido adenosine (308 Da, Ligand)
- Soluble cytochrome b562,adenosine receptor (Complex)
Cryo-EM structure of human TMEM120A in the CoASH-bound state
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7f3t
Q-score: 0.443
Rong Y, Jiang J, Gao Y, Guo J, Song D, Liu W, Zhang M, Zhao Y, Xiao B, Liu Z
eLife (2021) 10 [ DOI: doi:10.7554/eLife.71474 Pubmed: 34409941 ]
- Transmembrane protein 120a (Cell from Homo sapiens)
- Transmembrane protein 120a (44 kDa, Protein from Homo sapiens)
- Coenzyme a (767 Da, Ligand)
Cryo-EM structure of human TMEM120A in the CoASH-free state
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7f3u
Q-score: 0.335
Rong Y, Jiang J, Gao Y, Guo J, Song D, Liu W, Zhang M, Zhao Y, Xiao B, Liu Z
eLife (2021) 10 [ DOI: doi:10.7554/eLife.71474 Pubmed: 34409941 ]
- Transmembrane protein 120a (Cell from Homo sapiens)
- Transmembrane protein 120a (44 kDa, Protein from Homo sapiens)