Cryo-EM structure of human SIDT1 protein with C1 symmetry at neutral pH
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8woq
Q-score: 0.501
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ Pubmed: 38378654 DOI: doi:10.1038/s41421-024-00647-2 ]
- Water (18 Da, Ligand)
- Ternary complex of sidt1 in complex with unknown lipids (Complex from Homo sapiens)
- Octanoic acid (2-hydroxy-1-hydroxymethyl-heptadec-3-enyl)-amide (425 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Oleic acid (282 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of human SIDT1 protein with C2 symmetry at neutral pH
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8wor
Q-score: 0.533
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ Pubmed: 38378654 DOI: doi:10.1038/s41421-024-00647-2 ]
- Water (18 Da, Ligand)
- Ternary complex of sidt1 in complex with unknown lipids (Complex from Homo sapiens)
- Octanoic acid (2-hydroxy-1-hydroxymethyl-heptadec-3-enyl)-amide (425 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Oleic acid (282 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of human SIDT1 protein with C1 symmetry at low pH
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 8wos
Q-score: 0.418
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ Pubmed: 38378654 DOI: doi:10.1038/s41421-024-00647-2 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Human sidt1 at low ph (Complex from Homo sapiens)
Cryo-EM structure of human SIDT1 protein with C2 symmetry at low pH
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8wot
Q-score: 0.458
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ Pubmed: 38378654 DOI: doi:10.1038/s41421-024-00647-2 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Human sidt1 at low ph (Complex from Homo sapiens)
Adenosine receptor bound to an agonist in complex with G protein obtained by cryo-EM
Resolution: 2.99 Å
EM Method: Single-particle
Fitted PDBs: 7xy6
Q-score: 0.468
Chen Y, Zhang J, Weng Y, Xu Y, Lu W, Liu W, Liu M, Hua T, Song G
Sci Adv (2022) 8 pp. eadd3709-eadd3709 [ DOI: doi:10.1126/sciadv.add3709 Pubmed: 36563137 ]
- Soluble cytochrome b562,adenosine receptor a2b,lgbit (69 kDa, Protein from Oplophorus gracilirostris)
- 2-[6-azanyl-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylethanamide (379 Da, Ligand)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,adenosine receptor a2b,lgbit (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- G protein (Complex from Oplophorus gracilirostris)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Adenosine receptor bound to an agonist in complex with g protein obtained by cryo-em (Complex from Homo sapiens)
Adenosine receptor bound to a non-selective agonist in complex with a G protein obtained by cryo-EM
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 7xy7
Q-score: 0.443
Chen Y, Zhang J, Weng Y, Xu Y, Lu W, Liu W, Liu M, Hua T, Song G
Sci Adv (2022) 8 pp. eadd3709-eadd3709 [ DOI: doi:10.1126/sciadv.add3709 Pubmed: 36563137 ]
- Soluble cytochrome b562,adenosine receptor a2b,lgbit (69 kDa, Protein from Oplophorus gracilirostris)
- Adenosine receptor a2b bound to a non-selective agonist in complex with g protein obtained by cryo-em (Complex from Homo sapiens)
- G protein (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- N-ethyl-5'-carboxamido adenosine (308 Da, Ligand)
- Soluble cytochrome b562,adenosine receptor (Complex)
Cryo-EM structure of human TMEM120A in the CoASH-bound state
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7f3t
Q-score: 0.443
Rong Y, Jiang J, Gao Y, Guo J, Song D, Liu W, Zhang M, Zhao Y, Xiao B, Liu Z
eLife (2021) 10 [ DOI: doi:10.7554/eLife.71474 Pubmed: 34409941 ]
- Transmembrane protein 120a (Cell from Homo sapiens)
- Transmembrane protein 120a (44 kDa, Protein from Homo sapiens)
- Coenzyme a (767 Da, Ligand)
Cryo-EM structure of human TMEM120A in the CoASH-free state
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7f3u
Q-score: 0.335
Rong Y, Jiang J, Gao Y, Guo J, Song D, Liu W, Zhang M, Zhao Y, Xiao B, Liu Z
eLife (2021) 10 [ DOI: doi:10.7554/eLife.71474 Pubmed: 34409941 ]
- Transmembrane protein 120a (Cell from Homo sapiens)
- Transmembrane protein 120a (44 kDa, Protein from Homo sapiens)
SARS-CoV-2 spike in complex with the CA521 neutralizing antibody Fab (focused refinement on Fab-RBD)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7e23
Q-score: 0.487
Song D, Wang W, Dong C, Ning Z, Liu X, Liu C, Du G, Sha C, Wang K, Lu J, Sun B, Zhao Y, Wang Q, Xu H, Li Y, Shen Z, Jiao J, Wang R, Tian J, Liu W, Wang L, Deng YQ, Dou C
Commun Biol (2021) 4 pp. 500-500 [ DOI: doi:10.1038/s42003-021-02029-w Pubmed: 33893388 ]
- Ca521 fab-rbd sub-complex (Complex)
- Ca521 light chain (23 kDa, Protein from Homo sapiens)
- Spike protein s1 2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Ca521 heavy chain (49 kDa, Protein from Homo sapiens)
- Ca521 heavy chain (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ca521 light chain (Complex from Homo sapiens)