Cryo-EM structure of NADPH oxidase 2 in complex with p22phox and EROS
Liang S, Liu A, Liu Y, Wang F, Zhou Y, Long Y, Wang T, Liu Z, Ren R, Ye RD
PNAS (2024) 121 pp. e2320388121-e2320388121 [ DOI: doi:10.1073/pnas.2320388121 Pubmed: 38805284 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cytochrome b-245 light chain (14 kDa, Protein from Homo sapiens)
- Monoclonal antibody 7g5 light chain (23 kDa, Protein from Oryctolagus cuniculus)
- Nadph oxidase 2 in complex with cytochrome b-245 light chain, cytochrome b-245 chaperone 1 and a monoclonal antibody (Complex from Homo sapiens)
- Cytochrome b-245 heavy chain (64 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Monoclonal antibody 7g5 heavy chain (23 kDa, Protein from Oryctolagus cuniculus)
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (760 Da, Ligand)
- Cytochrome b-245 chaperone 1 (18 kDa, Protein from Homo sapiens)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
Cryo-EM structure of TOC-TIC supercomplex from Chlamydomonas reinhardtii
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 7xzi
Q-score: 0.517
Liu H, Li A, Rochaix JD, Liu Z
Nature (2023) 615 pp. 349-357 [ DOI: doi:10.1038/s41586-023-05744-y Pubmed: 36702157 ]
- Digitonin (1 kDa, Ligand)
- Simp3 (21 kDa, Protein from Chlamydomonas reinhardtii)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Unknown peptide (1 kDa, Protein from Chlamydomonas reinhardtii)
- Hexadecane (226 Da, Ligand)
- Tic214 (232 kDa, Protein from Chlamydomonas reinhardtii)
- Toc75 (87 kDa, Protein from Chlamydomonas reinhardtii)
- Tic56 (28 kDa, Protein from Chlamydomonas reinhardtii)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Ctap3 (51 kDa, Protein from Chlamydomonas reinhardtii)
- Ctap4 (39 kDa, Protein from Chlamydomonas reinhardtii)
- Ctap5 (42 kDa, Protein from Chlamydomonas reinhardtii)
- Simp2 (13 kDa, Protein from Chlamydomonas reinhardtii)
- Protein tic 20 (29 kDa, Protein from Chlamydomonas reinhardtii)
- Toc34 (44 kDa, Protein from Chlamydomonas reinhardtii)
- Toc90 (102 kDa, Protein from Chlamydomonas reinhardtii)
- Tic100 (105 kDa, Protein from Chlamydomonas reinhardtii)
- Dodecane (170 Da, Ligand)
- A membrane protein complex (812 kDa, Complex from Chlamydomonas reinhardtii)
- Tic15 (14 kDa, Protein from Chlamydomonas reinhardtii)
- Inositol hexakisphosphate (660 Da, Ligand)
Cryo-EM structure of TOC complex from Chlamydomonas reinhardtii.
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 7xzj
Q-score: 0.433
Liu H, Li A, Rochaix JD, Liu Z
Nature (2023) 615 pp. 349-357 [ DOI: doi:10.1038/s41586-023-05744-y Pubmed: 36702157 ]
- Structure of a outer membrane protein complex (Complex from Chlamydomonas reinhardtii)
- Toc75 (87 kDa, Protein from Chlamydomonas reinhardtii)
- Tic214 (232 kDa, Protein from Chlamydomonas reinhardtii)
- Toc34 (44 kDa, Protein from Chlamydomonas reinhardtii)
- Toc90 (102 kDa, Protein from Chlamydomonas reinhardtii)
- Unknown peptide (2 kDa, Protein from Chlamydomonas reinhardtii)
- Toc39 (39 kDa, Protein from Chlamydomonas reinhardtii)
- Tic100 (105 kDa, Protein from Chlamydomonas reinhardtii)
- Inositol hexakisphosphate (660 Da, Ligand)
- Ctap3 (51 kDa, Protein from Chlamydomonas reinhardtii)
Computational design of a potent Epstein-Barr virus fusion protein gB nanoparticle vaccine
Computational design of a potent Epstein-Barr virus fusion protein gB nanoparticle vaccine
SARS-CoV-2 Spike in complex with neutralizing Fab 2B04 (one up, two down conformation)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7k9h
Q-score: 0.455
Errico JM, Zhao H, Chen RE, Liu Z, Case JB, Ma M, Schmitz AJ, Rau MJ, Fitzpatrick JAJ, Shi PY, Diamond MS, Whelan SPJ, Ellebedy AH, Fremont DH
Cell Rep (2021) 37 pp. 109881-109881 [ Pubmed: 34655519 DOI: doi:10.1016/j.celrep.2021.109881 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of sars-cov-2 spike with fab fragments of neutralizing antibody 2b04 (Complex)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2b04 light chain (11 kDa, Protein from Mus musculus)
- 2b04 heavy chain (13 kDa, Protein from Mus musculus)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab fragment of neutralizing monoclonal antibody 2b04 (Complex from Homo sapiens)
SARS-CoV-2 Spike RBD in complex with neutralizing Fab 2B04 (local refinement)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7k9i
Q-score: 0.476
Errico JM, Zhao H, Chen RE, Liu Z, Case JB, Ma M, Schmitz AJ, Rau MJ, Fitzpatrick JAJ, Shi PY, Diamond MS, Whelan SPJ, Ellebedy AH, Fremont DH
Cell Rep (2021) 37 pp. 109881-109881 [ Pubmed: 34655519 DOI: doi:10.1016/j.celrep.2021.109881 ]
- Fab fragment of monoclonal antibody 2b04 (Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 2b04 light chain (11 kDa, Protein from Mus musculus)
- 2b04 heavy chain (13 kDa, Protein from Mus musculus)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Complex of sars-cov-2 spike with fab fragment of monoclonal antibody 2b04 (Complex)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Spike in complex with neutralizing Fab 2H04 (three down conformation)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7k9j
Q-score: 0.457
Errico JM, Zhao H, Chen RE, Liu Z, Case JB, Ma M, Schmitz AJ, Rau MJ, Fitzpatrick JAJ, Shi PY, Diamond MS, Whelan SPJ, Ellebedy AH, Fremont DH
Cell Rep (2021) 37 pp. 109881-109881 [ Pubmed: 34655519 DOI: doi:10.1016/j.celrep.2021.109881 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 2h04 heavy chain (13 kDa, Protein from Mus musculus)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Complex of sars-cov-2 spike with fab fragments of neutralizing antibody 2h04 (Complex)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2h04 light chain (11 kDa, Protein from Mus musculus)
- Fab fragments of neutralizing antibody 2h04 (Complex from Mus musculus)
SARS-CoV-2 Spike RBD in complex with neutralizing Fab 2H04 (local refinement)
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 7k9k
Q-score: 0.475
Errico JM, Zhao H, Chen RE, Liu Z, Case JB, Ma M, Schmitz AJ, Rau MJ, Fitzpatrick JAJ, Shi PY, Diamond MS, Whelan SPJ, Ellebedy AH, Fremont DH
Cell Rep (2021) 37 pp. 109881-109881 [ Pubmed: 34655519 DOI: doi:10.1016/j.celrep.2021.109881 ]
- 2h04 heavy chain (13 kDa, Protein from Mus musculus)
- Complex of sars-cov-2 spike rbd with fab fragment of monoclonal antibody 2h04 (Complex)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab fragment of monoclonal antibody 2h04 (Complex from Mus musculus)
- Sars-cov-2 spike rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2h04 light chain (11 kDa, Protein from Mus musculus)
