CryoEM structure of human XPR1 in complex with phosphate in state A
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9j51
Q-score: 0.468
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ Pubmed: 39747008 DOI: doi:10.1038/s41467-024-55471-9 ]
- Human xpr1 (Complex from Homo sapiens)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Phosphate ion (94 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
CryoEM structure of human XPR1 in complex with phosphate in state B
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9j52
Q-score: 0.468
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ Pubmed: 39747008 DOI: doi:10.1038/s41467-024-55471-9 ]
- Human xpr1 (Complex from Homo sapiens)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Phosphate ion (94 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
CryoEM structure of human XPR1 in complex with phosphate in state C
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9j53
Q-score: 0.413
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ Pubmed: 39747008 DOI: doi:10.1038/s41467-024-55471-9 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
CryoEM structure of human XPR1 in apo state
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9j4x
Q-score: 0.554
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ Pubmed: 39747008 DOI: doi:10.1038/s41467-024-55471-9 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
Cryo-EM structure of the yeast TOM core complex crosslinked by BS3 (from TOM-TIM23 complex)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8w5k
Q-score: 0.436
Wang Q, Zhuang J, Huang R, Guan Z, Yan L, Hong S, Zhang L, Huang C, Liu Z, Yin P
Cell Discov (2024) 10 pp. 19-19 [ Pubmed: 38360717 DOI: doi:10.1038/s41421-023-00643-y ]
- Mitochondrial import receptor subunit tom40 (42 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Mitochondrial import receptor subunit tom22 (16 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Mitochondrial import receptor subunit tom7 (6 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Mitochondrial import receptor subunit tom5 (5 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Mitochondrial import receptor subunit tom6 (6 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- (2r)-3-{[(s)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl tetradecanoate (635 Da, Ligand)
- Tom-tim23 complex (Complex from Saccharomyces cerevisiae S288C)
Cryo-EM structure of the yeast TOM core complex (from TOM-TIM23 complex)
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 8w5j
Q-score: 0.281
Wang Q, Zhuang J, Huang R, Guan Z, Yan L, Hong S, Zhang L, Huang C, Liu Z, Yin P
Cell Discov (2024) 10 pp. 19-19 [ Pubmed: 38360717 DOI: doi:10.1038/s41421-023-00643-y ]
- Mitochondrial import receptor subunit tom40 (42 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Mitochondrial import receptor subunit tom22 (16 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Mitochondrial import receptor subunit tom7 (6 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Mitochondrial import receptor subunit tom5 (5 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Tom-tim23 complex (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Mitochondrial import receptor subunit tom6 (6 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- (2r)-3-{[(s)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl tetradecanoate (635 Da, Ligand)
Cryo-EM structure of VTC complex
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7ytj
Q-score: 0.485
Guan Z, Chen J, Liu R, Chen Y, Xing Q, Du Z, Cheng M, Hu J, Zhang W, Mei W, Wan B, Wang Q, Zhang J, Cheng P, Cai H, Cao J, Zhang D, Yan J, Yin P, Hothorn M, Liu Z
Nat Commun (2023) 14 pp. 718-718 [ DOI: doi:10.1038/s41467-023-36466-4 Pubmed: 36759618 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Vacuolar transporter chaperone 1 (15 kDa, Protein from Saccharomyces cerevisiae)
- Vtc complex (Complex from Saccharomyces cerevisiae)
- Vacuolar transporter chaperone 4 (86 kDa, Protein from Saccharomyces cerevisiae)
- Inositol hexakisphosphate (660 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Vacuolar transporter chaperone 3 (100 kDa, Protein from Saccharomyces cerevisiae)
Cryo-EM structure of SAH-bound MTA1-MTA9-p1-p2 complex
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7yi8
Q-score: 0.499
Yan J, Liu F, Guan Z, Yan X, Jin X, Wang Q, Wang Z, Yan J, Zhang D, Liu Z, Wu S, Yin P
Cell Discov (2023) 9 pp. 8-8 [ DOI: doi:10.1038/s41421-022-00516-w Pubmed: 36658132 ]
- P1 (41 kDa, Protein from Tetrahymena thermophila SB210)
- Mt-a70 family protein (42 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (19 kDa, Protein from Tetrahymena thermophila SB210)
- Mta9 (52 kDa, Protein from Tetrahymena thermophila SB210)
- Mtac holoenzyme (Complex from Tetrahymena thermophila SB210)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
Cryo-EM structure of SAM-bound MTA1-MTA9-p1-p2 complex
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7yi9
Q-score: 0.522
Yan J, Liu F, Guan Z, Yan X, Jin X, Wang Q, Wang Z, Yan J, Zhang D, Liu Z, Wu S, Yin P
Cell Discov (2023) 9 pp. 8-8 [ DOI: doi:10.1038/s41421-022-00516-w Pubmed: 36658132 ]
- S-adenosylmethionine (398 Da, Ligand)
- Mt-a70 family protein (42 kDa, Protein from Tetrahymena thermophila SB210)
- Mta9 (52 kDa, Protein from Tetrahymena thermophila SB210)
- P1 (41 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (19 kDa, Protein from Tetrahymena thermophila SB210)
- Mtac holoenzyme (Complex from Tetrahymena thermophila SB210)
Cryo-EM structure of the yeast mitochondrial SAM-Tom40 complex at 3.0 angstrom
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 7e4h
Q-score: 0.445
Wang Q, Guan Z, Qi L, Zhuang J, Wang C, Hong S, Yan L, Wu Y, Cao X, Cao J, Yan J, Zou T, Liu Z, Zhang D, Yan C, Yin P
Science (2021) 373 pp. 1377-1381 [ Pubmed: 34446444 DOI: doi:10.1126/science.abh0704 ]
- Sorting assembly machinery 37 kda subunit (40 kDa, Protein from Saccharomyces cerevisiae S288c)
- Sorting assembly machinery subunits (Complex from Saccharomyces cerevisiae S288c)
- Mitochondrial import receptor subunit tom40 (46 kDa, Protein from Saccharomyces cerevisiae S288c)
- Sorting assembly machinery 35 kda subunit (37 kDa, Protein from Saccharomyces cerevisiae S288c)
- Sorting assembly machinery 50 kda subunit (54 kDa, Protein from Saccharomyces cerevisiae S288c)
- Sam-tom40 complex (Complex from Saccharomyces cerevisiae S288c)
- Mitochondrial import receptor subunit tom40 (Complex)