Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9asd
Q-score: 0.506
Rosen LE, Tortorici MA, De Marco A, Pinto D, Foreman WB, Taylor AL, Park YJ, Bohan D, Rietz T, Errico JM, Hauser K, Dang HV, Chartron JW, Giurdanella M, Cusumano G, Saliba C, Zatta F, Sprouse KR, Addetia A, Zepeda SK, Brown J, Lee J, Dellota Jr E, Rajesh A, Noack J, Tao Q, DaCosta Y, Tsu B, Acosta R, Subramanian S, de Melo GD, Kergoat L, Zhang I, Liu Z, Guarino B, Schmid MA, Schnell G, Miller JL, Lempp FA, Czudnochowski N, Cameroni E, Whelan SPJ, Bourhy H, Purcell LA, Benigni F, di Iulio J, Pizzuto MS, Lanzavecchia A, Telenti A, Snell G, Corti D, Veesler D, Starr TN
Cell (2024) 187 pp. 7196- [ DOI: doi:10.1016/j.cell.2024.09.026 Pubmed: 39383863 ]
- Vir-7229 fab light chain (11 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Homo sapiens)
- Vir-7229 fab heavy chain (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ba 2.86 rbd - s2v29 complex (local refinement) (Complex from Sarbecovirus)
VIR-7229 Fab fragment bound the BA.2.86 spike trimer (global refinement)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9au2
Q-score: 0.499
Rosen LE, Tortorici MA, De Marco A, Pinto D, Foreman WB, Taylor AL, Park YJ, Bohan D, Rietz T, Errico JM, Hauser K, Dang HV, Chartron JW, Giurdanella M, Cusumano G, Saliba C, Zatta F, Sprouse KR, Addetia A, Zepeda SK, Brown J, Lee J, Dellota Jr E, Rajesh A, Noack J, Tao Q, DaCosta Y, Tsu B, Acosta R, Subramanian S, de Melo GD, Kergoat L, Zhang I, Liu Z, Guarino B, Schmid MA, Schnell G, Miller JL, Lempp FA, Czudnochowski N, Cameroni E, Whelan SPJ, Bourhy H, Purcell LA, Benigni F, di Iulio J, Pizzuto MS, Lanzavecchia A, Telenti A, Snell G, Corti D, Veesler D, Starr TN
Cell (2024) 187 pp. 7196- [ DOI: doi:10.1016/j.cell.2024.09.026 Pubmed: 39383863 ]
- Vir-7229 fab light chain (23 kDa, Protein from Homo sapiens)
- Vir-7229 fab heavy chain (24 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Ba.2.86 spike glycoprotein in complex with vir-7229 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8k0c
Q-score: 0.397
Fan P, Sun M, Zhang X, Zhang H, Liu Y, Yao Y, Li M, Fang T, Sun B, Chen Z, Chi X, Chen L, Peng C, Chen Z, Zhang G, Ren Y, Liu Z, Li Y, Li J, Li E, Guan W, Li S, Gong R, Zhang K, Yu C, Chiu S
Nat Commun (2024) 15 pp. 4330-4330 [ DOI: doi:10.1038/s41467-024-48601-w Pubmed: 38773072 ]
- Heavy chain of 1e5 fab fragments (26 kDa, Protein from Macaca mulatta)
- Glycoprotein g (56 kDa, Protein from Nipah virus)
- Cryo-em structure of conformation 1 of complex of nipah virus attachment glycoprotein g with 1e5 neutralizing antibody (Complex from Nipah virus)
- Light chain of 1e5 fab fragments (23 kDa, Protein from Macaca mulatta)
- Glycoprotein g (6 kDa, Protein from Nipah virus)
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8iwp
Q-score: 0.346
Wu M, Wu C, Song T, Pan K, Wang Y, Liu Z
Cell Res (2023) 33 pp. 533-545 [ Pubmed: 37258749 DOI: doi:10.1038/s41422-023-00827-x ]
- Calcium-transporting atpase type 2c member 1 (100 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Secretory pathway ca(2+)-transporting atpase type 1 (Complex from Homo sapiens)
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 8iwr
Q-score: 0.39
Wu M, Wu C, Song T, Pan K, Wang Y, Liu Z
Cell Res (2023) 33 pp. 533-545 [ Pubmed: 37258749 DOI: doi:10.1038/s41422-023-00827-x ]
- Magnesium ion (24 Da, Ligand)
- Secretory pathway ca(2+)-transporting atpase type 1 (Complex from Homo sapiens)
- Calcium-transporting atpase type 2c member 1 (100 kDa, Protein from Homo sapiens)
- Phosphomethylphosphonic acid adenylate ester (505 Da, Ligand)
- Calcium ion (40 Da, Ligand)
Resolution: 3.42 Å
EM Method: Single-particle
Fitted PDBs: 8iws
Q-score: 0.396
Wu M, Wu C, Song T, Pan K, Wang Y, Liu Z
Cell Res (2023) 33 pp. 533-545 [ Pubmed: 37258749 DOI: doi:10.1038/s41422-023-00827-x ]
- Magnesium ion (24 Da, Ligand)
- Secretory pathway ca(2+)-transporting atpase type 1 (Complex from Homo sapiens)
- Beryllium trifluoride ion (66 Da, Ligand)
- Calcium-transporting atpase type 2c member 1 (100 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8iwt
Q-score: 0.452
Wu M, Wu C, Song T, Pan K, Wang Y, Liu Z
Cell Res (2023) 33 pp. 533-545 [ Pubmed: 37258749 DOI: doi:10.1038/s41422-023-00827-x ]
- Beryllium trifluoride ion (66 Da, Ligand)
- Calcium-transporting atpase type 2c member 1 (100 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Secretory pathway ca(2+)-transporting atpase type 1 (Complex from Homo sapiens)
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 8iwu
Q-score: 0.452
Wu M, Wu C, Song T, Pan K, Wang Y, Liu Z
Cell Res (2023) 33 pp. 533-545 [ Pubmed: 37258749 DOI: doi:10.1038/s41422-023-00827-x ]
- Calcium-transporting atpase type 2c member 1 (100 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Secretory pathway ca(2+)-transporting atpase type 1 (Complex from Homo sapiens)
Resolution: 3.71 Å
EM Method: Single-particle
Fitted PDBs: 8iww
Q-score: 0.34
Wu M, Wu C, Song T, Pan K, Wang Y, Liu Z
Cell Res (2023) 33 pp. 533-545 [ Pubmed: 37258749 DOI: doi:10.1038/s41422-023-00827-x ]
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Secretory pathway ca(2+)-transporting atpase type 1 (Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Calcium-transporting atpase type 2c member 1 (97 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
Local refined cryo-EM reconstruction of Omicron BA.5 RBD in complex with 8-9D Fab
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8j1t
Q-score: 0.455
Tai W, Yang K, Liu Y, Li R, Feng S, Chai B, Zhuang X, Qi S, Shi H, Liu Z, Lei J, Ma E, Wang W, Tian C, Le T, Wang J, Chen Y, Tian M, Xiang Y, Yu G, Cheng G
Nat Commun (2023) 14 pp. 8042-8042 [ DOI: doi:10.1038/s41467-023-43798-8 Pubmed: 38052844 ]
- Severe acute respiratory syndrome coronavirus 2 omicron ba.5 rbd bound 8-9d fab (22 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov2 omicron ba.5 rbd (Complex)
- 8-9d heavy chain (12 kDa, Protein from Homo sapiens)
- 8-9d light chain (11 kDa, Protein from Homo sapiens)
- 8-9d fab (Complex from Homo sapiens)
- Spike protein (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)