Cryo-EM of helical fibers formed by two peptides Pyn-K6 and Pyn-(EY)3
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 9d70
Q-score: 0.39
Qiao Y, Zia A, Wu G, Liu Z, Guo J, Chu M, He H, Wang F, Xu B
J Am Chem Soc (2025) 147 pp. 2978-2983 [ Pubmed: 39808585 DOI: doi:10.1021/jacs.4c12150 ]
- Pyr-ey3 (1 kDa, Protein from synthetic construct)
- Pyn-k6 + pyn-ey3 fiber (Complex from synthetic construct)
- (pyren-1-yl)acetic acid (260 Da, Ligand)
- Pyr-k6 (1 kDa, Protein from synthetic construct)
CryoEM structure of human XPR1 in complex with phosphate in state A
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9j51
Q-score: 0.468
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- Phosphate ion (94 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
CryoEM structure of human XPR1 in complex with phosphate in state B
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9j52
Q-score: 0.468
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- Phosphate ion (94 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
CryoEM structure of human XPR1 in complex with phosphate in state C
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9j53
Q-score: 0.413
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- Phosphate ion (94 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
Cryo-EM structure of human ELAC2
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8z0p
Q-score: 0.463
Nucleic Acids Res (2024) 52 pp. 13434-13446 [ Pubmed: 39494506 DOI: doi:10.1093/nar/gkae1014 ]
- Zinc phosphodiesterase elac protein 2 (92 kDa, Protein from Homo sapiens)
- Elac2 protein (Complex from Homo sapiens)
- Phosphate ion (94 Da, Ligand)
- Zinc ion (65 Da, Ligand)
Cryo-EM structure of human ELAC2-pre-tRNA
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8z1g
Q-score: 0.338
Nucleic Acids Res (2024) 52 pp. 13434-13446 [ Pubmed: 39494506 DOI: doi:10.1093/nar/gkae1014 ]
- Phosphate ion (94 Da, Ligand)
- Zinc phosphodiesterase elac protein 2 (92 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Trna (Complex)
- Elac2-trna (Complex from Homo sapiens)
- Elac2 (Complex)
- Homo sapiens mitochondrion pre-trna-tyr (27 kDa, RNA from Homo sapiens)
ATAT-2 bound MEC-12/MEC-7 microtubule
Luo J, Lam WH, Yu D, Chao VC, Zopfi MN, Khoo CJ, Zhao C, Yan S, Liu Z, Li XD, Zheng C, Zhai Y, Ti SC
Nat Struct Mol Biol (2025) 32 pp. 358-368 [ Pubmed: 39496813 DOI: doi:10.1038/s41594-024-01406-3 ]
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Tubulin alpha-3 chain (50 kDa, Protein from Caenorhabditis elegans)
- Alpha-tubulin n-acetyltransferase 2 (30 kDa, Protein from Caenorhabditis elegans)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Mec-12/mec-7 microtubule in complex with full-length atat-2 (Complex from Caenorhabditis elegans)
- Tubulin beta-1 chain (49 kDa, Protein from Caenorhabditis elegans)
- Tubulin alpha-3 chain (50 kDa, Protein from Caenorhabditis elegans)
ATAT-2 bound MEC-12/MEC-7 microtubule without acetyl-CoA
Luo J, Lam WH, Yu D, Chao VC, Zopfi MN, Khoo CJ, Zhao C, Yan S, Liu Z, Li XD, Zheng C, Zhai Y, Ti SC
Nat Struct Mol Biol (2025) 32 pp. 358-368 [ Pubmed: 39496813 DOI: doi:10.1038/s41594-024-01406-3 ]
- Alpha tat2 bound mec-12/mec-7 microtubules withour acetyl-coa (Complex from Caenorhabditis elegans)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Tubulin alpha-3 chain (50 kDa, Protein from Caenorhabditis elegans)
- Alpha-tubulin n-acetyltransferase 2 (30 kDa, Protein from Caenorhabditis elegans)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta-1 chain (49 kDa, Protein from Caenorhabditis elegans)
- Piperazine-n,n'-bis(2-ethanesulfonic acid) (302 Da, Ligand)
ATAT-2 bound K40Q MEC-12/MEC-7 microtubule
Luo J, Lam WH, Yu D, Chao VC, Zopfi MN, Khoo CJ, Zhao C, Yan S, Liu Z, Li XD, Zheng C, Zhai Y, Ti SC
Nat Struct Mol Biol (2025) 32 pp. 358-368 [ Pubmed: 39496813 DOI: doi:10.1038/s41594-024-01406-3 ]
- K40q mec-12/mec-7 microtubule complexed with alpha tat2 (Complex from Caenorhabditis elegans)
- Tubulin alpha-3 chain (50 kDa, Protein from Caenorhabditis elegans)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Alpha-tubulin n-acetyltransferase 2 (30 kDa, Protein from Caenorhabditis elegans)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Acetyl coenzyme *a (809 Da, Ligand)
- Tubulin beta-1 chain (49 kDa, Protein from Caenorhabditis elegans)
ATAT-2 bound K40R MEC-12/MEC-7 microtubule
Luo J, Lam WH, Yu D, Chao VC, Zopfi MN, Khoo CJ, Zhao C, Yan S, Liu Z, Li XD, Zheng C, Zhai Y, Ti SC
Nat Struct Mol Biol (2025) 32 pp. 358-368 [ Pubmed: 39496813 DOI: doi:10.1038/s41594-024-01406-3 ]
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Tubulin alpha-3 chain (50 kDa, Protein from Caenorhabditis elegans)
- Alpha-tubulin n-acetyltransferase 2 (30 kDa, Protein from Caenorhabditis elegans)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Acetyl coenzyme *a (809 Da, Ligand)
- Tubulin beta-1 chain (49 kDa, Protein from Caenorhabditis elegans)
- K40r mec-12/mec-7 microtubule in complex with luminal atat-2 (Complex from Caenorhabditis elegans)