Vibrio cholerae DdmD-DdmE holo complex
Loeff L, Adams DW, Chanez C, Stutzmann S, Righi L, Blokesch M, Jinek M
Science (2024) 385 pp. 188-194 [ Pubmed: 38870273 DOI: 10.1126/science.adq0534 ]
Image sets:
Vibrio cholerae DdmD apo complex
Loeff L, Adams DW, Chanez C, Stutzmann S, Righi L, Blokesch M, Jinek M
Science (2024) 385 pp. 188-194 [ Pubmed: 38870273 DOI: 10.1126/science.adq0534 ]
Image sets:
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 8ps4
Q-score: 0.466
Loeff L, Walter A, Rosalen GT, Jinek M
Cell (2025) 188 pp. 721- [ DOI: doi:10.1016/j.cell.2024.11.030 Pubmed: 39742808 ]
- Shedu effector protein (47 kDa, Protein from Escherichia coli KTE10)
- Magnesium ion (24 Da, Ligand)
- Tetrameric sdua complex (194 kDa, Cellular component from Escherichia coli KTE10)
Escherichia coli SduA complex bound to DNA
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8ps5
Q-score: 0.517
Loeff L, Walter A, Rosalen GT, Jinek M
Cell (2025) 188 pp. 721- [ DOI: doi:10.1016/j.cell.2024.11.030 Pubmed: 39742808 ]
- Tetrameric sdua complex (194 kDa, Complex)
- Sdua (Complex from Escherichia coli KTE10)
- 40 nt dna substrate (12 kDa, DNA from synthetic construct)
- Dna (Complex from synthetic construct)
- Shedu effector protein (47 kDa, Protein from Escherichia coli KTE10)
Cryo-EM structure of human tRNA ligase RTCB in complex with human PYROXD1.
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8orj
Q-score: 0.41
Loeff L, Kroupova A, Asanovic I, Boneberg F, Pfleiderer MM, Ferdigg A, Ackle F, Martinez J, Jinek M
bioRxiv (2023) [ DOI: doi:10.1101/2023.04.06.535761 ]
- Magnesium ion (24 Da, Ligand)
- Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
- Dihydroflavine-adenine dinucleotide (787 Da, Ligand)
- Cryo-em structure of human rtcb in complex with human pyroxd1. (Complex from Homo sapiens)
- Rna-splicing ligase rtcb homolog (55 kDa, Protein from Homo sapiens)
- Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (56 kDa, Protein from Homo sapiens)
Vibrio cholerae DdmD-DdmE holo complex
Loeff L, Adams DW, Chanez C, Stutzmann S, Righi L, Blokesch M, Jinek M
Science (2024) 385 pp. 188-194 [ Pubmed: 38870273 DOI: doi:10.1126/science.adq0534 ]
- 14 nucleotide dna guide with terminal 5' phosphate (4 kDa, DNA from synthetic construct)
- Target dna strand (20 kDa, DNA from synthetic construct)
- Magnesium ion (24 Da, Ligand)
- Vibrio cholerae ddme (79 kDa, Protein from Vibrio cholerae)
- Non-target dna strand (20 kDa, DNA from synthetic construct)
- Ddmd-ddme holocomplex (Complex from Vibrio cholerae)
- Helicase/uvrb n-terminal domain-containing protein (136 kDa, Protein from Vibrio cholerae)
Vibrio cholerae DdmD apo complex
Resolution: 2.55 Å
EM Method: Single-particle
Fitted PDBs: 9ezx
Q-score: 0.506
Loeff L, Adams DW, Chanez C, Stutzmann S, Righi L, Blokesch M, Jinek M
Science (2024) 385 pp. 188-194 [ Pubmed: 38870273 DOI: doi:10.1126/science.adq0534 ]
- Dimeric complex of the ddmd protein (266 kDa, Complex from Vibrio cholerae)
- Helicase/uvrb n-terminal domain-containing protein (136 kDa, Protein from Vibrio cholerae)
SpCas9 bound to 18 nucleotide complementary DNA substrate in the checkpoint state
Pacesa M, Loeff L, Querques I, Muckenfuss LM, Sawicka M, Jinek M
Nature (2022) 609 pp. 191-196 [ DOI: 10.1038/s41586-022-05114-0 Pubmed: 36002571 ]
Image sets:
SpCas9 bound to 6 nucleotide complementary DNA substrate
Pacesa M, Loeff L, Querques I, Muckenfuss LM, Sawicka M, Jinek M
Nature (2022) 609 pp. 191-196 [ DOI: 10.1038/s41586-022-05114-0 Pubmed: 36002571 ]
Image sets:
SpCas9 bound to 12 nucleotide complementary DNA substrate
Pacesa M, Loeff L, Querques I, Muckenfuss LM, Sawicka M, Jinek M
Nature (2022) 609 pp. 191-196 [ DOI: 10.1038/s41586-022-05114-0 Pubmed: 36002571 ]
Image sets: