HsPepT1 bound to Ala-Phe in the outward facing occluded conformation
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7pmw
Q-score: 0.36
Killer M, Wald J, Pieprzyk J, Marlovits TC, Low C
Sci Adv (2021) 7 pp. eabk3259-eabk3259 [ Pubmed: 34730990 DOI: doi:10.1126/sciadv.abk3259 ]
- Solute carrier family 15 member 1 (78 kDa, Protein from Homo sapiens)
- Ala-phe (Complex from Homo sapiens)
- Ala-phe (236 Da, Protein from Homo sapiens)
- Human pept1 (Complex from Homo sapiens)
HsPepT1 bound to Ala-Phe in the outward facing open conformation
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7pmx
Q-score: 0.44
Killer M, Wald J, Pieprzyk J, Marlovits TC, Low C
Sci Adv (2021) 7 pp. eabk3259-eabk3259 [ Pubmed: 34730990 DOI: doi:10.1126/sciadv.abk3259 ]
- Solute carrier family 15 member 1 (78 kDa, Protein from Homo sapiens)
- Ala-phe (Complex from Homo sapiens)
- Ala-phe (236 Da, Protein from Homo sapiens)
- Human pept1 (Complex from Homo sapiens)
HsPepT2 bound to Ala-Phe in the inward facing partially occluded conformation
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7pmy
Q-score: 0.388
Killer M, Wald J, Pieprzyk J, Marlovits TC, Low C
Sci Adv (2021) 7 pp. eabk3259-eabk3259 [ Pubmed: 34730990 DOI: doi:10.1126/sciadv.abk3259 ]
- Human pept2 (Complex from Homo sapiens)
- Ala-phe (236 Da, Protein from Homo sapiens)
- Solute carrier family 15 member 2 (81 kDa, Protein from Homo sapiens)
- Ala-phe (Complex from Homo sapiens)
Apo HsPepT1 in the outward facing open conformation
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7pn1
Q-score: 0.402
Killer M, Wald J, Pieprzyk J, Marlovits TC, Low C
Sci Adv (2021) 7 pp. eabk3259-eabk3259 [ Pubmed: 34730990 DOI: doi:10.1126/sciadv.abk3259 ]
- Solute carrier family 15 member 1 (78 kDa, Protein from Homo sapiens)
- Human pept1 (Complex from Homo sapiens)
Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23)
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 7a25
Q-score: 0.386
Custodio TF, Das H, Sheward DJ, Hanke L, Pazicky S, Pieprzyk J, Sorgenfrei M, Schroer MA, Gruzinov AY, Jeffries CM, Graewert MA, Svergun DI, Dobrev N, Remans K, Seeger MA, McInerney GM, Murrell B, Hallberg BM, Low C
Nat Commun (2020) 11 pp. 5588-5588 [ DOI: doi:10.1038/s41467-020-19204-y Pubmed: 33149112 ]
- Spike glycoprotein (126 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike glycoprotein in 1-up conformation bound by 3 neutralising sybodies (sb23) (Complex)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Neutralising sybody (sb23) (Complex from synthetic construct)
- Sybody 23 (12 kDa, Protein from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 7a29
Q-score: 0.398
Custodio TF, Das H, Sheward DJ, Hanke L, Pazicky S, Pieprzyk J, Sorgenfrei M, Schroer MA, Gruzinov AY, Jeffries CM, Graewert MA, Svergun DI, Dobrev N, Remans K, Seeger MA, McInerney GM, Murrell B, Hallberg BM, Low C
Nat Commun (2020) 11 pp. 5588-5588 [ DOI: doi:10.1038/s41467-020-19204-y Pubmed: 33149112 ]
- Sars-cov-2 spike glycoprotein in 1-up conformation bound by 3 neutralising sybodies (sb23) (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Neutralising sybody (sb23) (12 kDa, Protein from synthetic construct)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Neutralising sybody (sb23) (Complex from synthetic construct)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)