CryoEM structure of ZIKV rsNS1
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8wn8
Q-score: 0.33
Chew BLA, Ngoh AQ, Phoo WW, Weng MJG, Sheng HJ, Chan KWK, Tan EYJ, Gelbart T, Xu C, Tan GS, Vasudevan SG, Luo D
Npj Viruses (2024) 2 pp. 14- [ DOI: doi:10.1038/s44298-024-00024-6 ]
- Non-structural protein 1 (41 kDa, Protein from Zika virus)
- Zika virus (Virus from Zika virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
ZIKV rsNS1 in complex with Fab AA12 and anti-fab nanobody
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8wnp
Q-score: 0.428
Chew BLA, Ngoh AQ, Phoo WW, Weng MJG, Sheng HJ, Chan KWK, Tan EYJ, Gelbart T, Xu C, Tan GS, Vasudevan SG, Luo D
Npj Viruses (2024) 2 pp. 14- [ DOI: doi:10.1038/s44298-024-00024-6 ]
- Non-structural protein 1 (40 kDa, Protein from Zika virus)
- Vh chains (23 kDa, Protein from Homo sapiens)
- Vl chains (23 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zikv rsns1 in complex with fab aa12 and anti-fab nanobody (Complex from Zika virus)
ZIKV rsNS1 in complex with Fab GB5 and anti-fab nanobody
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8wnu
Q-score: 0.331
Chew BLA, Ngoh AQ, Phoo WW, Weng MJG, Sheng HJ, Chan KWK, Tan EYJ, Gelbart T, Xu C, Tan GS, Vasudevan SG, Luo D
Npj Viruses (2024) 2 pp. 14- [ DOI: doi:10.1038/s44298-024-00024-6 ]
- Non-structural protein 1 (40 kDa, Protein from Zika virus)
- Vl (23 kDa, Protein from Homo sapiens)
- Zikv rsns1 in complex with fab gb5 and anti-fab nanobody (Complex from Zika virus)
- Vh (23 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
CryoEM structure of ZIKV rsNS1 filament
Resolution: 8.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8wo0
Q-score: 0.088
Chew BLA, Ngoh AQ, Phoo WW, Weng MJG, Sheng HJ, Chan KWK, Tan EYJ, Gelbart T, Xu C, Tan GS, Vasudevan SG, Luo D
Npj Viruses (2024) 2 pp. 14- [ DOI: doi:10.1038/s44298-024-00024-6 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Non-structural protein 1 (40 kDa, Protein from Zika virus)
- Zikv recombinantly secreted ns1 filament (Complex from Zika virus)
ZIKV rsNS1 in complex with Fab EB9 and anti-fab nanobody
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8wo4
Q-score: 0.416
Chew BLA, Ngoh AQ, Phoo WW, Weng MJG, Sheng HJ, Chan KWK, Tan EYJ, Gelbart T, Xu C, Tan GS, Vasudevan SG, Luo D
Npj Viruses (2024) 2 pp. 14- [ DOI: doi:10.1038/s44298-024-00024-6 ]
- Zikv rsns1 in complex with fab aa12 and anti-fab nanobody (Complex from Homo sapiens)
- Non-structural protein 1 (41 kDa, Protein from Zika virus)
- Anti-fab nanobody (15 kDa, Protein from Lama glama)
- Vl (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Vh (24 kDa, Protein from Homo sapiens)
Structural insights into the membrane microdomain organization by SPFH family proteins
Resolution: 3.27 Å
EM Method: Single-particle
Fitted PDBs: 7vhp
Q-score: 0.383
Ma C, Wang C, Luo D, Yan L, Yang W, Li N, Gao N
Cell Res (2022) 32 pp. 176-189 [ Pubmed: 34975153 DOI: doi:10.1038/s41422-021-00598-3 ]
- Atp-dependent zinc metalloprotease ftsh (70 kDa, Protein from Escherichia coli)
- Kcf complex (Complex from Escherichia coli)
- Modulator of ftsh protease hflc (37 kDa, Protein from Escherichia coli)
- Protein hflk (45 kDa, Protein from Escherichia coli)
Structural insights into the membrane microdomain organization by SPFH family proteins
Resolution: 3.27 Å
EM Method: Single-particle
Fitted PDBs: 7vhq
Q-score: 0.464
Ma C, Wang C, Luo D, Yan L, Yang W, Li N, Gao N
Cell Res (2022) 32 pp. 176-189 [ Pubmed: 34975153 DOI: doi:10.1038/s41422-021-00598-3 ]
- Modulator of ftsh protease hflc (37 kDa, Protein from Escherichia coli)
- Atp-dependent zinc metalloprotease ftsh (7 kDa, Protein from Escherichia coli)
- Protein hflk (30 kDa, Protein from Escherichia coli)
- Kcf complex (Complex from Escherichia coli)
MDA5 CARDs-MAVS CARD polyUb complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7dni
Q-score: 0.497
Song B, Chen Y, Liu X, Yuan F, Tan EYJ, Lei Y, Song N, Han Y, Pascal BD, Griffin PR, Luo C, Wu B, Luo D, Zheng J
Immunity (2021) 54 pp. 2218- [ DOI: doi:10.1016/j.immuni.2021.09.008 Pubmed: 34644557 ]
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- K63-polyub bound mda5cards-mavscard complex (Complex from Homo sapiens)
- Mitochondrial antiviral-signaling protein (11 kDa, Protein from Homo sapiens)
- Interferon-induced helicase c domain-containing protein 1 (23 kDa, Protein from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7dnj
Q-score: 0.48
Song B, Chen Y, Liu X, Yuan F, Tan EYJ, Lei Y, Song N, Han Y, Pascal BD, Griffin PR, Luo C, Wu B, Luo D, Zheng J
Immunity (2021) 54 pp. 2218- [ DOI: doi:10.1016/j.immuni.2021.09.008 Pubmed: 34644557 ]
- Interferon-induced helicase c domain-containing protein 1 (23 kDa, Protein from Homo sapiens)
- K63polyub (Complex from Homo sapiens)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Mda5 cards (Complex)
- K63polyub bound mda5 cards complex (Complex from Homo sapiens)