Cryo-EM structure of human ZnT1, in the absence of zinc, determined in outward-facing conformation
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 8zsb
Q-score: 0.487
Li Y, Ma J, Wang R, Luo Y, Zheng S, Wang X
Cell Metab. (2024) 36 pp. 2118- [ Pubmed: 39111308 DOI: doi:10.1016/j.cmet.2024.07.009 ]
- Cryo-em structure of the znt1 in the apo state (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Proton-coupled zinc antiporter slc30a1 (55 kDa, Protein from Homo sapiens)
Cryo-EM structure of human ZnT1, in the presence of zinc, determined in outward-facing conformation
Li Y, Ma J, Wang R, Luo Y, Zheng S, Wang X
Cell Metab. (2024) 36 pp. 2118- [ Pubmed: 39111308 DOI: doi:10.1016/j.cmet.2024.07.009 ]
- Zinc ion (65 Da, Ligand)
- Proton-coupled zinc antiporter slc30a1 (55 kDa, Protein from Homo sapiens)
- Cryo-em structure of the znt1 in the presence of zinc (Complex from Homo sapiens)
Banach BB, Cerutti G, Fahad AS, Shen CH, Oliveira De Souza M, Katsamba PS, Tsybovsky Y, Wang P, Nair MS, Huang Y, Francino-Urdániz IM, Steiner PJ, Gutiérrez-González M, Liu L, López Acevedo SN, Nazzari AF, Wolfe JR, Luo Y, Olia AS, Teng IT, Yu J, Zhou T, Reddem ER, Bimela J, Pan X, Madan B, Laflin AD, Nimrania R, Yuen KY, Whitehead TA, Ho DD, Kwong PD, Shapiro L, DeKosky BJ
Cell Rep (2021) 37 [ Pubmed: 34587480 DOI: 10.1016/j.celrep.2021.109771 ]
Image sets:
Banach BB, Cerutti G, Fahad AS, Shen CH, Oliveira De Souza M, Katsamba PS, Tsybovsky Y, Wang P, Nair MS, Huang Y, Francino-Urdániz IM, Steiner PJ, Gutiérrez-González M, Liu L, López Acevedo SN, Nazzari AF, Wolfe JR, Luo Y, Olia AS, Teng IT, Yu J, Zhou T, Reddem ER, Bimela J, Pan X, Madan B, Laflin AD, Nimrania R, Yuen KY, Whitehead TA, Ho DD, Kwong PD, Shapiro L, DeKosky BJ
Cell Rep (2021) 37 [ Pubmed: 34587480 DOI: 10.1016/j.celrep.2021.109771 ]
Image sets:
Structure of the wild-type Arabidopsis ABCB19 in the apo state
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8woi
Q-score: 0.49
Ying W, Wang Y, Wei H, Luo Y, Ma Q, Zhu H, Janssens H, Vukasinovic N, Kvasnica M, Winne JM, Gao Y, Tan S, Friml J, Liu X, Russinova E, Sun L
Science (2024) 383 pp. eadj4591-eadj4591 [ DOI: doi:10.1126/science.adj4591 Pubmed: 38513023 ]
Structure of the wild-type Arabidopsis ABCB19 in the brassinolide-bound state
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8wom
Q-score: 0.451
Ying W, Wang Y, Wei H, Luo Y, Ma Q, Zhu H, Janssens H, Vukasinovic N, Kvasnica M, Winne JM, Gao Y, Tan S, Friml J, Liu X, Russinova E, Sun L
Science (2024) 383 pp. eadj4591-eadj4591 [ DOI: doi:10.1126/science.adj4591 Pubmed: 38513023 ]
Structure of the wild-type Arabidopsis ABCB19 in the brassinolide and AMP-PNP bound state
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8woo
Q-score: 0.401
Ying W, Wang Y, Wei H, Luo Y, Ma Q, Zhu H, Janssens H, Vukasinovic N, Kvasnica M, Winne JM, Gao Y, Tan S, Friml J, Liu X, Russinova E, Sun L
Science (2024) 383 pp. eadj4591-eadj4591 [ DOI: doi:10.1126/science.adj4591 Pubmed: 38513023 ]
- Abc transporter b family member 19 (136 kDa, Protein from Arabidopsis thaliana)
- Purified wild-type abcb19 protein in complex with brassinolide and amp-pnp (Cellular component from Arabidopsis thaliana)
- Magnesium ion (24 Da, Ligand)
- Brassinolide (480 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Structure of the Arabidopsis E529Q/E1174Q ABCB19 in the ATP bound state
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8wp0
Q-score: 0.464
Ying W, Wang Y, Wei H, Luo Y, Ma Q, Zhu H, Janssens H, Vukasinovic N, Kvasnica M, Winne JM, Gao Y, Tan S, Friml J, Liu X, Russinova E, Sun L
Science (2024) 383 pp. eadj4591-eadj4591 [ DOI: doi:10.1126/science.adj4591 Pubmed: 38513023 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Abc transporter b family member 19 (136 kDa, Protein from Arabidopsis thaliana)
- Purified e529q/e1174q mutant abcb19 protein in complex with atp (Cellular component from Arabidopsis thaliana)
- Magnesium ion (24 Da, Ligand)
Complex Structure of Arginine Kinase McsB and McsA from Staphylococcus aureus
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 8gqd
Q-score: 0.359
Lu K, Luo B, Tao X, Luo Y, Ao M, Zheng B, Xu X, Ma X, Niu J, Li H, Xie Y, Zhao Z, Zheng P, Wang G, Gao S, Wang C, Xia W, Su Z, Mao ZW
Nat Chem Biol (2024) [ DOI: doi:10.1038/s41589-024-01720-3 Pubmed: 39232187 ]
- Protein-arginine kinase (38 kDa, Protein from Staphylococcus aureus)
- Mcsa-mcsb complex (Complex from Staphylococcus aureus)
- Protein-arginine kinase activator protein (6 kDa, Protein from Staphylococcus aureus)
- Zinc ion (65 Da, Ligand)
Senktide bound to active human neurokinin 3 receptor in complex with Gq
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8jbf
Q-score: 0.524
Sun W, Yang F, Zhang H, Yuan Q, Ling S, Wang Y, Lv P, Li Z, Luo Y, Liu D, Yin W, Shi P, Xu HE, Tian C
Cell Discov (2023) 9 pp. 66-66 [ Pubmed: 37391393 DOI: doi:10.1038/s41421-023-00564-w ]
- Senktide bound to active human neurokinin 3 receptor in complex with gq heterotrimer (Complex from Homo sapiens)
- Guanine nucleotide-binding protein gq subunit alpha (41 kDa, Protein from Homo sapiens)
- Neuromedin-k receptor (44 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (41 kDa, Protein from Rattus norvegicus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Scfv16 nanobody (32 kDa, Protein from Mus musculoides)
- Senktide (915 Da, Protein from Homo sapiens)