Local refined cryo-EM reconstruction of Omicron BA.5 RBD in complex with 8-9D Fab
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8j1t
Q-score: 0.455
Tai W, Yang K, Liu Y, Li R, Feng S, Chai B, Zhuang X, Qi S, Shi H, Liu Z, Lei J, Ma E, Wang W, Tian C, Le T, Wang J, Chen Y, Tian M, Xiang Y, Yu G, Cheng G
Nat Commun (2023) 14 pp. 8042-8042 [ DOI: doi:10.1038/s41467-023-43798-8 Pubmed: 38052844 ]
- Severe acute respiratory syndrome coronavirus 2 omicron ba.5 rbd bound 8-9d fab (22 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov2 omicron ba.5 rbd (Complex)
- 8-9d heavy chain (12 kDa, Protein from Homo sapiens)
- 8-9d light chain (11 kDa, Protein from Homo sapiens)
- 8-9d fab (Complex from Homo sapiens)
- Spike protein (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM reconstruction of SARS-CoV2 Omicron BA.5 spike in complex with 8-9D Fabs
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 8j1v
Q-score: 0.374
Tai W, Yang K, Liu Y, Li R, Feng S, Chai B, Zhuang X, Qi S, Shi H, Liu Z, Lei J, Ma E, Wang W, Tian C, Le T, Wang J, Chen Y, Tian M, Xiang Y, Yu G, Cheng G
Nat Commun (2023) 14 pp. 8042-8042 [ DOI: doi:10.1038/s41467-023-43798-8 Pubmed: 38052844 ]
- Sars-cov2 omicron ba.5 spike ectodomain (Complex)
- 8-9d heavy chain (12 kDa, Protein from Homo sapiens)
- Severe acute respiratory syndrome coronavirus 2 omicron ba.5 spike bound 8-9d fab (369 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- 8-9d light chain (11 kDa, Protein from Homo sapiens)
- Spike protein s2' (123 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 8-9d fab variable region (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6ny1
Q-score: 0.368
Liu JJ, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Jonathan C, Tan D, Knott G, Wanger A, Harrington L, Nogales E, Doudna JA
Nature (2019) 566 pp. 218-223 [ ]
CasX ternary complex with 30bp target DNA
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6ny3
Q-score: 0.465
Liu JJ, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Chuck J, Tan D, Knott GJ, Harrington LB, Al-Shayeb B, Wagner A, Brotzmann J, Staahl BT, Taylor KL, Desmarais J, Nogales E, Doudna JA
Nature (2019) 566 pp. 218-223 [ DOI: doi:10.1038/s41586-019-0908-x Pubmed: 30718774 ]
- Casx ternary complex with 30bp target dna (Complex from Deltaproteobacteria)
- Casx (113 kDa, Protein from Deltaproteobacteria bacterium)
- Rna (122-mer) (39 kDa, RNA from Deltaproteobacteria bacterium)
- Dna (24-mer) (7 kDa, DNA from Deltaproteobacteria bacterium)
- Dna (30-mer) (9 kDa, DNA from Deltaproteobacteria bacterium)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6ny2
Q-score: 0.472
Liu JJ, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Chuck J, Tan D, Knott GJ, Harrington LB, Al-Shayeb B, Wagner A, Brotzmann J, Staahl BT, Taylor KL, Desmarais J, Nogales E, Doudna JA
Nature (2019) 566 pp. 218-223 [ DOI: doi:10.1038/s41586-019-0908-x Pubmed: 30718774 ]
- Casx-grna-dna(45bp) state i (Complex from Deltaproteobacteria)
- Casx (113 kDa, Protein from Deltaproteobacteria bacterium RIFCSPLOWO2 12 FULL 43 16)
- Dna (35-mer) (10 kDa, DNA from Deltaproteobacteria)
- Dna (35-mer) (10 kDa, DNA from Deltaproteobacteria)
- Rna (112-mer) (35 kDa, RNA from Deltaproteobacteria)