CryoEM structure of human XPR1 in complex with phosphate in state A
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9j51
Q-score: 0.468
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
CryoEM structure of human XPR1 in complex with phosphate in state B
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9j52
Q-score: 0.468
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
CryoEM structure of human XPR1 in complex with phosphate in state C
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9j53
Q-score: 0.413
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
Cryo-EM structure of the DHA bound FFA1-Gi complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9k1c
Q-score: 0.462
Ke Y, Huang Y, Yi C, Ma L, Chu X, Wu B, Zhao Q, Han S
Cell Rep (2024) 43 pp. 115024-115024 [ DOI: doi:10.1016/j.celrep.2024.115024 Pubmed: 39616615 ]
- Free fatty acid receptor 1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Dha bound ffa1-gi complex (Complex from Homo sapiens)
- Docosa-4,7,10,13,16,19-hexaenoic acid (328 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
Cryo-EM structure of the butyrate bound FFA2-Gi complex
Resolution: 3.34 Å
EM Method: Single-particle
Fitted PDBs: 9k1d
Q-score: 0.478
Ke Y, Huang Y, Yi C, Ma L, Chu X, Wu B, Zhao Q, Han S
Cell Rep (2024) 43 pp. 115024-115024 [ DOI: doi:10.1016/j.celrep.2024.115024 Pubmed: 39616615 ]
- Butanoic acid (88 Da, Ligand)
- Cryo-em structure of the butyrate bound ffa2-gi complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Free fatty acid receptor 2 (42 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
CryoEM structure of human XPR1 in apo state
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9j4x
Q-score: 0.554
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
Structure of mumps virus nucleoprotein without C-arm
Shan H, Su X, Li T, Qin Y, Zhang N, Yang L, Ma L, Bai Y, Qi L, Liu Y, Shen QT
Commun Biol (2021) 4 pp. 833-833 [ Pubmed: 34215847 DOI: doi:10.1038/s42003-021-02362-0 ]
- Truncated mumps virus ncleocapsid (Complex from Mumps rubulavirus)
- Rna (5'-r(p*up*up*up*up*up*u)-3') (1 kDa, RNA from Escherichia coli)
- Nucleoprotein (61 kDa, Protein from Mumps virus (strain Jeryl-Lynn))
Cryo-EM structure of the wild-type alpha-synuclein fibril.
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 8oqi
Q-score: 0.562
Pesch V, Flores-Fernandez JM, Reithofer S, Ma L, Ozduzenciler P, Busch Y, Sriraman A, Wang Y, Amidian S, Kroepel CVM, Muller L, Lien Y, Rudtke O, Frieg B, Schroder GF, Wille H, Tamguney G
Brain (2024) 147 pp. 1644-1652 [ Pubmed: 38428032 DOI: doi:10.1093/brain/awae061 ]
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Human wild-type alpha-synuclein fibril (Complex from Homo sapiens)
Cryo-EM structure of PfAgo-guide DNA-target DNA complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8jpx
Q-score: 0.575
Wang L, Chen W, Zhang C, Xie X, Huang F, Chen M, Mao W, Yu N, Wei Q, Ma L, Li Z
Mol Cell (2024) 84 pp. 675-686.e4 [ Pubmed: 38295801 DOI: doi:10.1016/j.molcel.2024.01.004 ]
- Guide dna (5 kDa, DNA from Pyrococcus furiosus DSM 3638)
- Protein argonaute (90 kDa, Protein from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1))
- Excess dna (1 kDa, DNA from Pyrococcus furiosus DSM 3638)
- Cryo-em structure of a pfago-guide dna-target dna complex (Complex from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1))
- Magnesium ion (24 Da, Ligand)
- Target dna (5 kDa, DNA from Pyrococcus furiosus DSM 3638)
Cryo-EM structure of TtdAgo-guide DNA-target DNA complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8wd8
Q-score: 0.593
Wang L, Chen W, Zhang C, Xie X, Huang F, Chen M, Mao W, Yu N, Wei Q, Ma L, Li Z
Mol Cell (2024) 84 pp. 675-686.e4 [ Pubmed: 38295801 DOI: doi:10.1016/j.molcel.2024.01.004 ]
- Dna binding protein (Complex)
- Dna (Complex)
- Cryo-em structure of ttdago-guide dna-target dna complex (Complex from Thermus thermophilus)
- Guide dna (5 kDa, DNA from Thermus thermophilus)
- Zinc ion (65 Da, Ligand)
- Target dna (5 kDa, DNA from Thermus thermophilus)
- Argonaute family protein (87 kDa, Protein from Thermococcus thioreducens)
- Magnesium ion (24 Da, Ligand)