Structure of the Xenorceptide A2-bound E. coli BAM complex (BamABCDE)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 9he1
Q-score: 0.333
Modaresi SM, Sugiyama R, Tram NDT, Jakob RP, Phan CS, Saei AA, Morishita Y, Muhlethaler T, Lim J, Ritz D, Long PSY, Lehner PA, Lim ZH, Degen M, Yao Z, Maier T, Hou Y, Lee JY, Xu J, Yeat AYJ, Koh KTS, Goh WY, Ling SYH, Chua PWL, Yamazaki M, Ee PLR, Hiller S, Morinaka BI
bioRxiv (2024) [ DOI: doi:10.1101/2024.12.16.628070 ]
- Outer membrane protein assembly factor bamc (36 kDa, Protein from Escherichia coli K-12)
- Outer membrane protein assembly factor bamb (42 kDa, Protein from Escherichia coli K-12)
- Outer membrane protein assembly factor bama (90 kDa, Protein from Escherichia coli K-12)
- Rsam-modified ripp, xyea family (1 kDa, Protein from synthetic construct)
- Outer membrane protein assembly factor bame (13 kDa, Protein from Escherichia coli K-12)
- Outer membrane protein assembly factor bamd (27 kDa, Protein from Escherichia coli K-12)
- Bam complex (Complex from Escherichia coli K-12)
cryo-EM structure of LST2 TOS peptide bound to human mTOR complex 1, focused on RAPTOR
Battaglioni S, Craigie LM, Filippini S, Maier T, Hall MN
PNAS (2024) 121 pp. e2405959121-e2405959121 [ Pubmed: 39141345 DOI: doi:10.1073/pnas.2405959121 ]
cryo-EM structure of human LST2 bound to human mTOR complex 1, focused on RAPTOR
Battaglioni S, Craigie LM, Filippini S, Maier T, Hall MN
PNAS (2024) 121 pp. e2405959121-e2405959121 [ Pubmed: 39141345 DOI: doi:10.1073/pnas.2405959121 ]
- Lateral signaling target protein 2 homolog (96 kDa, Protein from Homo sapiens)
- Regulatory-associated protein of mtor (152 kDa, Protein from Homo sapiens)
- Mtorc1 in complex with lst2 (Complex from Homo sapiens)
cryo-EM structure of LST2 TOS peptide bound to human mTOR complex 1
Battaglioni S, Craigie LM, Filippini S, Maier T, Hall MN
PNAS (2024) 121 pp. e2405959121-e2405959121 [ Pubmed: 39141345 DOI: doi:10.1073/pnas.2405959121 ]
- Lateral signaling target protein 2 homolog (1 kDa, Protein from Homo sapiens)
- Inositol hexakisphosphate (660 Da, Ligand)
- Regulatory-associated protein of mtor (152 kDa, Protein from Homo sapiens)
- Serine/threonine-protein kinase mtor (289 kDa, Protein from Homo sapiens)
- Target of rapamycin complex subunit lst8 (35 kDa, Protein from Homo sapiens)
- Mtorc1 in complex with lst2 tos peptide (Complex from Homo sapiens)
cryo-EM structure of human LST2 bound to human mTOR complex 1
Battaglioni S, Craigie LM, Filippini S, Maier T, Hall MN
PNAS (2024) 121 pp. e2405959121-e2405959121 [ Pubmed: 39141345 DOI: doi:10.1073/pnas.2405959121 ]
- Inositol hexakisphosphate (660 Da, Ligand)
- Lateral signaling target protein 2 homolog (96 kDa, Protein from Homo sapiens)
- Regulatory-associated protein of mtor (152 kDa, Protein from Homo sapiens)
- Serine/threonine-protein kinase mtor (289 kDa, Protein from Homo sapiens)
- Mtorc1 in complex with lst2 (Complex from Homo sapiens)
- Target of rapamycin complex subunit lst8 (35 kDa, Protein from Homo sapiens)
cryo-EM structure of human LST2 bound to human mTOR complex 1
Battaglioni S, Craigie LM, Filippini S, Maier T, Hall MN
PNAS (2024) 121 pp. e2405959121-e2405959121 [ Pubmed: 39141345 DOI: doi:10.1073/pnas.2405959121 ]
Cryo-EM structure of human LST2 bound to human mTOR complex 1, focused on one protomer
Battaglioni S, Craigie LM, Filippini S, Maier T, Hall MN
PNAS (2024) 121 pp. e2405959121-e2405959121 [ Pubmed: 39141345 DOI: doi:10.1073/pnas.2405959121 ]
Cryo-EM structure of human LST2 bound to human mTOR complex 1, focused on one protomer
Battaglioni S, Craigie LM, Filippini S, Maier T, Hall MN
PNAS (2024) 121 pp. e2405959121-e2405959121 [ Pubmed: 39141345 DOI: doi:10.1073/pnas.2405959121 ]
The organise full-length structure of the fungal non-reducing polyketide synthase (NR-PKS) PksA
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8cg4
Q-score: 0.552
To Be Published
- The full-length non-reducing polyketide synthase pksa (450 kDa, Complex from Aspergillus parasiticus)
- Norsolorinic acid synthase (237 kDa, Protein from Aspergillus parasiticus)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8cg5
Q-score: 0.562
To Be Published
- Non-reducing polyketide synthase ctb1 (140 kDa, Protein from Cercospora nicotianae)
- Acp crosslinked to the ks of the condensing region of the non-reducing polyketide synthase ctb1 (Complex from Cercospora nicotianae)
- Acyl carrier protein (acp) of non-reducing polyketide synthase ctb1 (9 kDa, Protein from Cercospora nicotianae)
- N~3~-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-n-[2-(propanoylamino)ethyl]-beta-alaninamide (397 Da, Ligand)