Resolution: 3.84 Å
EM Method: Single-particle
Fitted PDBs: 8csa
Q-score: 0.33
Gobeil SM-C, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders K, Edwards RJ, Korber B, Haynes BF, Henderson RC, Acharya P
Science (2021) [ DOI: doi:10.1126/science.abi6226 ]
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
bioRxiv (2022) [ DOI: doi:10.1101/2022.01.25.477784 Pubmed: 35118469 ]
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7tl1
Q-score: 0.441
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ Pubmed: 35447081 DOI: doi:10.1016/j.molcel.2022.03.028 ]
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7tl9
Q-score: 0.411
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ Pubmed: 35447081 DOI: doi:10.1016/j.molcel.2022.03.028 ]
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7tei
Q-score: 0.464
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ Pubmed: 35447081 DOI: doi:10.1016/j.molcel.2022.03.028 ]
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 7tf8
Q-score: 0.468
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ Pubmed: 35447081 DOI: doi:10.1016/j.molcel.2022.03.028 ]
CryoEM map of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1042
Resolution: 3.42 Å
EM Method: Single-particle
Fitted PDBs: 7tht
Q-score: 0.407
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ Pubmed: 35447081 DOI: doi:10.1016/j.molcel.2022.03.028 ]
- Dh1042 light chain (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (124 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Antibody dh1042 (Complex from Homo sapiens)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Dh1042 heavy chain (13 kDa, Protein from Homo sapiens)
- Severe acute respiratory syndrome-related coronavirus spike glycoprotein in complex with rbd antibody dh1042 (Complex)
SARS-CoV-2 Spike Protein Trimer bound to DH1043 fab
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 7ljr
Q-score: 0.35
Li D, Edwards RJ, Manne K, Martinez DR, Schafer A, Alam SM, Wiehe K, Lu X, Parks R, Sutherland LL, Oguin TH, McDanal C, Perez LG, Mansouri K, Gobeil SMC, Janowska K, Stalls V, Kopp M, Cai F, Lee E, Foulger A, Hernandez GE, Sanzone A, Tilahun K, Jiang C, Tse LV, Bock KW, Minai M, Nagata BM, Cronin K, Gee-Lai V, Deyton M, Barr M, Von Holle T, Macintyre AN, Stover E, Feldman J, Hauser BM, Caradonna TM, Scobey TD, Moody MA, Cain DW, DeMarco CT, Denny TN, Woods CW, Petzold EW, Schmidt AG, Teng IT, Zhou T, Kwong PD, Mascola JR, Graham BS, Moore IN, Seder R, Andersen H, Lewis MG, Montefiori DC, Sempowski GD, Baric RS, Acharya P, Haynes BF, Saunders KO
bioRxiv (2021) [ Pubmed: 33442694 DOI: doi:10.1101/2020.12.31.424729 ]
- Fab dh1043 heavy chain (51 kDa, Protein from Homo sapiens)
- Spike protein trimer bound to the dh1043 antibody (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab dh1043 light chain (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 7lwi
Q-score: 0.454
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ DOI: doi:10.1126/science.abi6226 Pubmed: 34168071 ]
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 7lwj
Q-score: 0.363
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ DOI: doi:10.1126/science.abi6226 Pubmed: 34168071 ]