DH270.6 Fab bound to the HIV-1 CH848 DE3 SOSIP
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8vgv
Q-score: 0.453
Henderson R, Anasti K, Manne K, Stalls V, Saunders C, Bililign Y, Williams A, Bubphamala P, Montani M, Kachhap S, Li J, Jaing C, Newman A, Cain DW, Lu X, Venkatayogi S, Berry M, Wagh K, Korber B, Saunders KO, Tian M, Alt F, Wiehe K, Acharya P, Alam SM, Haynes BF
Nat Commun (2024) 15 pp. 9503-9503 [ DOI: doi:10.1038/s41467-024-53120-9 Pubmed: 39489734 ]
- Ch848 de3 sosip gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Antibody fab bound hiv-1 ectodomain (Complex from Human immunodeficiency virus 1)
- Dh270.6 antibody fab heavy chain (14 kDa, Protein from Homo sapiens)
- Dh270.6 antibody fab light chain (11 kDa, Protein from Homo sapiens)
- Ch848 de3 sosip gp120 (51 kDa, Protein from Human immunodeficiency virus 1)
VRC01 Fab bound to the HIV-1 CH848 DE3 SOSIP
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8vgw
Q-score: 0.426
Henderson R, Anasti K, Manne K, Stalls V, Saunders C, Bililign Y, Williams A, Bubphamala P, Montani M, Kachhap S, Li J, Jaing C, Newman A, Cain DW, Lu X, Venkatayogi S, Berry M, Wagh K, Korber B, Saunders KO, Tian M, Alt F, Wiehe K, Acharya P, Alam SM, Haynes BF
Nat Commun (2024) 15 pp. 9503-9503 [ DOI: doi:10.1038/s41467-024-53120-9 Pubmed: 39489734 ]
- Antibody fab bound hiv-1 ectodomain (Complex from Human immunodeficiency virus 1)
- Ch848 de3 sosip gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Ch848 de3 sosip gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Vrc01 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Vrc01 fab light chain (11 kDa, Protein from Homo sapiens)
CH235.12 Fab bound to the HIV-1 CH505.M5 SOSIP
Resolution: 4.08 Å
EM Method: Single-particle
Fitted PDBs: 8vh1
Q-score: 0.404
Henderson R, Anasti K, Manne K, Stalls V, Saunders C, Bililign Y, Williams A, Bubphamala P, Montani M, Kachhap S, Li J, Jaing C, Newman A, Cain DW, Lu X, Venkatayogi S, Berry M, Wagh K, Korber B, Saunders KO, Tian M, Alt F, Wiehe K, Acharya P, Alam SM, Haynes BF
Nat Commun (2024) 15 pp. 9503-9503 [ DOI: doi:10.1038/s41467-024-53120-9 Pubmed: 39489734 ]
- Ch505.m5 sosip gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Antibody fab bound hiv-1 ectodomain (Complex from Human immunodeficiency virus 1)
- Ch235.i60 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Ch505.m5 sosip gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Ch235.i60 fab light chain (23 kDa, Protein from Homo sapiens)
CH235.12 Fab bound to the HIV-1 CH505.M5 SOSIP
Resolution: 4.31 Å
EM Method: Single-particle
Fitted PDBs: 8vh2
Q-score: 0.32
Henderson R, Anasti K, Manne K, Stalls V, Saunders C, Bililign Y, Williams A, Bubphamala P, Montani M, Kachhap S, Li J, Jaing C, Newman A, Cain DW, Lu X, Venkatayogi S, Berry M, Wagh K, Korber B, Saunders KO, Tian M, Alt F, Wiehe K, Acharya P, Alam SM, Haynes BF
Nat Commun (2024) 15 pp. 9503-9503 [ DOI: doi:10.1038/s41467-024-53120-9 Pubmed: 39489734 ]
- Envelope glycoprotein gp160 (18 kDa, Protein from Human immunodeficiency virus 1)
- Antibody fab bound hiv-1 ectodomain (Complex from Human immunodeficiency virus 1)
- Ch235.12 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Ch235.12 fab light chain (23 kDa, Protein from Homo sapiens)
- Ch505.m5.g458y sosip gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
CH505.M5.G458Y CE2 Design SOSIP
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8vh3
Q-score: 0.433
Henderson R, Anasti K, Manne K, Stalls V, Saunders C, Bililign Y, Williams A, Bubphamala P, Montani M, Kachhap S, Li J, Jaing C, Newman A, Cain DW, Lu X, Venkatayogi S, Berry M, Wagh K, Korber B, Saunders KO, Tian M, Alt F, Wiehe K, Acharya P, Alam SM, Haynes BF
Nat Commun (2024) 15 pp. 9503-9503 [ DOI: doi:10.1038/s41467-024-53120-9 Pubmed: 39489734 ]
- Ch505.ce2 sosip gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 ectodomain (Complex from Human immunodeficiency virus 1)
- Ch505.ce2 sosip gp120 (51 kDa, Protein from Human immunodeficiency virus 1)
Structure of SARS-CoV S protein in complex with Receptor Binding Domain antibody DH1047
Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 7sg4
Q-score: 0.355
Martinez DR, Schafer A, Gobeil S, Li D, De la Cruz G, Parks R, Lu X, Barr M, Stalls V, Janowska K, Beaudoin E, Manne K, Mansouri K, Edwards RJ, Cronin K, Yount B, Anasti K, Montgomery SA, Tang J, Golding H, Shen S, Zhou T, Kwong PD, Graham BS, Mascola JR, Montefiori DC, Alam SM, Sempowski G, Sempowski GD, Khurana S, Wiehe K, Saunders KO, Acharya P, Haynes BF, Baric RS
Sci Transl Med (2022) 14 pp. eabj7125-eabj7125 [ DOI: doi:10.1126/scitranslmed.abj7125 Pubmed: 34726473 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov s protein in complex with receptor binding domain antibody dh1047 (Complex from Severe acute respiratory syndrome-related coronavirus)
- Dh1047 light chain (24 kDa, Protein from Homo sapiens)
- Dh1047 heavy chain (24 kDa, Protein from Homo sapiens)
- Spike glycoprotein (140 kDa, Protein from Severe acute respiratory syndrome coronavirus)
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 7lwi
Q-score: 0.454
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ DOI: doi:10.1126/science.abi6226 Pubmed: 34168071 ]
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 7lwj
Q-score: 0.363
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ DOI: doi:10.1126/science.abi6226 Pubmed: 34168071 ]
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 7lwk
Q-score: 0.501
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ DOI: doi:10.1126/science.abi6226 Pubmed: 34168071 ]
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 7lwl
Q-score: 0.515
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ DOI: doi:10.1126/science.abi6226 Pubmed: 34168071 ]