Cholinephosphotransferase in complex with diacylglycerol in nanodisc
Roberts JR, Horibata Y, Kwarcinski FE, Lam V, Raczkowski AM, Hubbard A, White B, Sugimoto H, Tall GG, Ohi MD, Maeda S
Nat Commun (2025) 16 pp. 111-111 [ Pubmed: 39747155 DOI: doi:10.1038/s41467-024-55673-1 ]
- Nanobody24 (Complex from Lama glama)
- Cholinephosphotransferase 1 (Protein from Saccharomyces cerevisiae S288C)
- Ycpt1 (Complex from Saccharomyces cerevisiae)
- Saccharomyces cerevisiae cdp-choline phosphotransferase in complex with diacyl-glycerol (Complex from Saccharomyces cerevisiae)
Cholinephosphotransferase in complex with CDP-choline and phosphatidylcholine
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8urp
Q-score: 0.589
Roberts JR, Horibata Y, Kwarcinski FE, Lam V, Raczkowski AM, Hubbard A, White B, Sugimoto H, Tall GG, Ohi MD, Maeda S
Nat Commun (2025) 16 pp. 111-111 [ Pubmed: 39747155 DOI: doi:10.1038/s41467-024-55673-1 ]
- Nanobody25 (Complex from Lama glama)
- Cholinephosphotransferase 1 (44 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- [2-cytidylate-o'-phosphonyloxyl]-ethyl-trimethyl-ammonium (488 Da, Ligand)
- Ycpt1 (Complex from Saccharomyces cerevisiae)
- Water (18 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phoshocholine (734 Da, Ligand)
Cholinephosphotransferase in complex with selective inhibitor chelerythrine
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8urt
Q-score: 0.546
Roberts JR, Horibata Y, Kwarcinski FE, Lam V, Raczkowski AM, Hubbard A, White B, Sugimoto H, Tall GG, Ohi MD, Maeda S
Nat Commun (2025) 16 pp. 111-111 [ Pubmed: 39747155 DOI: doi:10.1038/s41467-024-55673-1 ]
- Nanobody25 (Complex from Lama glama)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Ycpt1 (Complex from Saccharomyces cerevisiae)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium (348 Da, Ligand)
- Cholinephosphotransferase 1 (44 kDa, Protein from Saccharomyces cerevisiae)
Cholinephosphotransferase in complex with diacylglycerol
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8ul9
Q-score: 0.503
Roberts JR, Horibata Y, Kwarcinski FE, Lam V, Raczkowski AM, Hubbard A, White B, Sugimoto H, Tall GG, Ohi MD, Maeda S
Nat Commun (2025) 16 pp. 111-111 [ Pubmed: 39747155 DOI: doi:10.1038/s41467-024-55673-1 ]
- Nanobody24 (Complex from Lama glama)
- Cholinephosphotransferase 1 (44 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Ycpt1 (Complex from Saccharomyces cerevisiae)
- Diacyl glycerol (625 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- Saccharomyces cerevisiae cdp-choline phosphotransferase in complex with diacyl-glycerol (Complex from Saccharomyces cerevisiae)