CryoEM structure of sNS1 complexed with Fab5E3
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7wur
Q-score: 0.427
Shu B, Ooi JSG, Tan AWK, Ng TS, Dejnirattisai W, Mongkolsapaya J, Fibriansah G, Shi J, Kostyuchenko VA, Screaton GR, Lok SM
Nat Commun (2022) 13 pp. 6756-6756 [ DOI: doi:10.1038/s41467-022-34415-1 Pubmed: 36347841 ]
- Dengue ns1 (Complex from Homo sapiens)
- Structure of dengue ns1 complexed with fab 5e3 (Complex from Dengue virus 2)
- Fab 5e3 heavy chain (12 kDa, Protein from Homo sapiens)
- Fab 5e3 (Complex)
- Fab 5e3 light chain (11 kDa, Protein from Homo sapiens)
- Core protein (38 kDa, Protein from Dengue virus 2)
CryoEM structure of a dimer of loose sNS1 tetramer
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7wus
Q-score: 0.402
Shu B, Ooi JSG, Tan AWK, Ng TS, Dejnirattisai W, Mongkolsapaya J, Fibriansah G, Shi J, Kostyuchenko VA, Screaton GR, Lok SM
Nat Commun (2022) 13 pp. 6756-6756 [ DOI: doi:10.1038/s41467-022-34415-1 Pubmed: 36347841 ]
- Dengue ns1 dimer of loose tetramer (Cellular component from Dengue virus 2)
- Core protein (38 kDa, Protein from Dengue virus 2)
CryoEM structure of stable sNS1 tetramer
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7wut
Q-score: 0.368
Shu B, Ooi JSG, Tan AWK, Ng TS, Dejnirattisai W, Mongkolsapaya J, Fibriansah G, Shi J, Kostyuchenko VA, Screaton GR, Lok SM
Nat Commun (2022) 13 pp. 6756-6756 [ DOI: doi:10.1038/s41467-022-34415-1 Pubmed: 36347841 ]
CryoEM structure of loose sNS1 tetramer
Resolution: 8.3 Å
EM Method: Single-particle
Fitted PDBs: 7wuu
Q-score: 0.101
Shu B, Ooi JSG, Tan AWK, Ng TS, Dejnirattisai W, Mongkolsapaya J, Fibriansah G, Shi J, Kostyuchenko VA, Screaton GR, Lok SM
Nat Commun (2022) 13 pp. 6756-6756 [ DOI: doi:10.1038/s41467-022-34415-1 Pubmed: 36347841 ]
CryoEM structure of sNS1 hexamer
Resolution: 8.0 Å
EM Method: Single-particle
Fitted PDBs: 7wuv
Q-score: 0.055
Shu B, Ooi JSG, Tan AWK, Ng TS, Dejnirattisai W, Mongkolsapaya J, Fibriansah G, Shi J, Kostyuchenko VA, Screaton GR, Lok SM
Nat Commun (2022) 13 pp. 6756-6756 [ DOI: doi:10.1038/s41467-022-34415-1 Pubmed: 36347841 ]
- Ns1 hexamer (Cellular component from Dengue virus 2)
- Core protein (34 kDa, Protein from Dengue virus 2)
Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 5h30
Q-score: 0.284
Zhang S, Kostyuchenko VA, Ng T-S, Lim X-N, Ooi JSG, Lambert S, Tan TY, Widman DG, Shi J, Baric RS, Lok S-M
Nat Commun (2016) 7 pp. 13679-13679 [ Pubmed: 27882950 DOI: doi:10.1038/ncomms13679 ]
- Igg c10 heavy chain (14 kDa, Protein from Homo sapiens)
- Zika virus (Complex from Zika virus)
- Structural protein e (54 kDa, Protein from Zika virus)
- Zika virus complexed with c10 fab at ph 6.5 (Complex)
- Fab c10 (Complex)
- Strutural protein m (8 kDa, Protein from Zika virus)
- Igg c10 light chain (11 kDa, Protein from Homo sapiens)
Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0
Resolution: 12.0 Å
EM Method: Single-particle
Fitted PDBs: 5h32
Q-score: 0.073
Zhang S, Kostyuchenko VA, Ng T-S, Lim X-N, Ooi JSG, Lambert S, Tan TY, Widman DG, Shi J, Baric RS, Lok S-M
Nat Commun (2016) 7 pp. 13679-13679 [ Pubmed: 27882950 DOI: doi:10.1038/ncomms13679 ]
- Zika virus complexed with fab c10 at ph 5.0 (Complex)
- C10 igg light chain variable region (11 kDa, Protein from Homo sapiens)
- C10 igg heavy chain variable region (14 kDa, Protein from Homo sapiens)
- Zika virus (Complex from Zika virus)
- Fab c10 (Complex)
- Structural protein e (44 kDa, Protein from Zika virus)
Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5h37
Q-score: 0.39
Zhang S, Kostyuchenko VA, Ng T-S, Lim X-N, Ooi JSG, Lambert S, Tan TY, Widman DG, Shi J, Baric RS, Lok S-M
Nat Commun (2016) 7 pp. 13679-13679 [ Pubmed: 27882950 DOI: doi:10.1038/ncomms13679 ]
- Structural protein e (54 kDa, Protein from Zika virus)
- C10 igg light chain variable region (11 kDa, Protein from Homo sapiens)
- C10 igg heavy chain variable region (14 kDa, Protein from Homo sapiens)
- C10 fab (Complex)
- Strutural protein m (8 kDa, Protein from Zika virus)
- Zika virus complexed with c10 fab at ph 8.0 (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zika virus (Complex from Zika virus)
Resolution: 6.5 Å
EM Method: Single-particle
Fitted PDBs: 4uif
Q-score: 0.188
Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JSG, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe JE, Lok SM
Science (2015) 349 pp. 88-91 [ Pubmed: 26138979 DOI: doi:10.1126/science.aaa8651 ]
Resolution: 20.0 Å
EM Method: Single-particle
Fitted PDBs: 4uih
Q-score: 0.016
Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JSG, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe JE, Lok SM
Science (2015) 349 pp. 88-91 [ Pubmed: 26138979 DOI: doi:10.1126/science.aaa8651 ]