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author:"Parey K" AND author_name:"Siegmund"
Cryo-EM structure of a respiratory complex I F89A mutant
Release date: Oct. 28, 2020
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 6y79
Q-score: 0.505
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 6y79
Q-score: 0.505
Galemou Yoga E, Parey K, Djurabekova A, Haapanen O, Siegmund K, Zwicker K, Sharma V, Zickermann V, Angerer H
Nat Commun (2020) 11 pp. 6008-6008 [ Pubmed: 33243981 DOI: doi:10.1038/s41467-020-19778-7 ]
Sample:
- Subunit nuam of nadh:ubiquinone oxidoreductase (complex i) (79 kDa, Protein from Yarrowia lipolytica)
- Subunit nucm of nadh:ubiquinone oxidoreductase (complex i) (52 kDa, Protein from Yarrowia lipolytica)
- Subunit nipm of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Yarrowia lipolytica)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Subunit nukm of nadh:ubiquinone oxidoreductase (complex i) (23 kDa, Protein from Yarrowia lipolytica)
- Subunit ni8m of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Mitochondrial nadh:ubiquinone oxidoreductase (1 MDa, Complex from Yarrowia lipolytica)
- Subunit nujm of nadh:ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Yarrowia lipolytica)
- Subunit nuvm of nadh:ubiquinone oxidoreductase (complex i) (7 kDa, Protein from Yarrowia lipolytica)
- Acyl carrier protein acpm1 of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Yarrowia lipolytica)
- Subunit nugm of nadh:ubiquinone oxidoreductase (complex i) (32 kDa, Protein from Yarrowia lipolytica)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit nu1m of nadh:ubiquinone oxidoreductase (complex i) (38 kDa, Protein from Yarrowia lipolytica)
- Subunit nesm of nadh:ubiquinone oxidoreductase (complex i) (28 kDa, Protein from Yarrowia lipolytica)
- Flavin mononucleotide (456 Da, Ligand)
- Subunit niam of nadh:ubiquinone oxidoreductase (complex i) (17 kDa, Protein from Yarrowia lipolytica)
- Subunit nupm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Acyl carrier protein acpm2 of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Subunit nufm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nuem of nadh:ubiquinone oxidoreductase (complex i) (42 kDa, Protein from Yarrowia lipolytica)
- Ubiquinone-9 (795 Da, Ligand)
- Subunit numm of protein nadh:ubiquinone oxidoreductase (complex i) (15 kDa, Protein from Yarrowia lipolytica)
- Subunit nb8m of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Yarrowia lipolytica)
- Subunit nb5m of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Yarrowia lipolytica)
- Subunit nuhm of nadh:ubiquinone oxidoreductase (complex i) (27 kDa, Protein from Yarrowia lipolytica)
- Subunit nimm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit n7bm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nuxm of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Yarrowia lipolytica)
- Subunit ni2m of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Yarrowia lipolytica)
- Subunit nunm of nadh:ubiquinone oxidoreductase (complex i) (13 kDa, Protein from Yarrowia lipolytica)
- Subunit nulm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nu6m of nadh:ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Yarrowia lipolytica)
- Subunit nuim of nadh:ubiquinone oxidoreductase (complex i) (25 kDa, Protein from Yarrowia lipolytica)
- Subunit ni9m of nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Phosphatidylinositol (887 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Subunit nubm of nadh:ubiquinone oxidoreductase (complex i) (53 kDa, Protein from Yarrowia lipolytica)
- Subunit nidm of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Yarrowia lipolytica)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Subunit nu5m of nadh:ubiquinone oxidoreductase (complex i) (73 kDa, Protein from Yarrowia lipolytica)
- Subunit nb4m of protein nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Subunit nuym of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Yarrowia lipolytica)
- Subunit nebm of nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Subunit nuum of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Diundecyl phosphatidyl choline (622 Da, Ligand)
- Subunit nb2m of nadh:ubiquinone oxidoreductase (complex i) (6 kDa, Protein from Yarrowia lipolytica)
- Subunit nb6m of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Subunit nu2m of nadh:ubiquinone oxidoreductase (complex i) (53 kDa, Protein from Yarrowia lipolytica)
- Subunit nuzm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Subunit nu4m of nadh:ubiquinone oxidoreductase (complex i) (54 kDa, Protein from Yarrowia lipolytica)
- (7r,17e,20e)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosa-17,20-dien-1-aminium 4-oxide (759 Da, Ligand)
- Subunit nu3m of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Iron/sulfur cluster (351 Da, Ligand)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Cryo-EM structure of respiratory complex I from Yarrowia lipolytica
Release date: Oct. 10, 2018
Resolution: 4.32 Å
EM Method: Single-particle
Fitted PDBs: 6gcs
Q-score: 0.371
Resolution: 4.32 Å
EM Method: Single-particle
Fitted PDBs: 6gcs
Q-score: 0.371
Parey K, Brandt U, Xie H, Mills DJ, Siegmund K, Vonck J, Kuehlbrandt W, Zickermann V
eLife (2018) 7 [ DOI: doi:10.7554/eLife.39213 Pubmed: 30277212 ]
Sample:
- Tyky subunit (nuim) (25 kDa, Protein from Yarrowia lipolytica)
- Nuym subunit (18 kDa, Protein from Yarrowia lipolytica)
- Cardiolipin (1 kDa, Ligand)
- Nidm subunit (11 kDa, Protein from Yarrowia lipolytica)
- Ni8m subunit (9 kDa, Protein from Yarrowia lipolytica)
- 24-kda subunit (nuhm) (27 kDa, Protein from Yarrowia lipolytica)
- Nd4 subunit (nu4m) (54 kDa, Protein from Yarrowia lipolytica)
- Nd4l subunit (nulm) (9 kDa, Protein from Yarrowia lipolytica)
- 75-kda protein (nuam) (79 kDa, Protein from Yarrowia lipolytica)
- Nuzm subunit (11 kDa, Protein from Yarrowia lipolytica)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Unknown subunit (4 kDa, Protein from Yarrowia lipolytica)
- Nesm subunit (13 kDa, Protein from Yarrowia lipolytica)
- Nd5 subunit (nu5m) (73 kDa, Protein from Yarrowia lipolytica)
- Acpm2 subunit (14 kDa, Protein from Yarrowia lipolytica)
- Niam subunit (8 kDa, Protein from Yarrowia lipolytica)
- Nb2m subunit (6 kDa, Protein from Yarrowia lipolytica)
- Nd1 subunit (nu1m) (38 kDa, Protein from Yarrowia lipolytica)
- Nd2 subunit (nu2m) (53 kDa, Protein from Yarrowia lipolytica)
- Nd3 subunit (nu3m) (14 kDa, Protein from Yarrowia lipolytica)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- 51-kda protein (nubm) (53 kDa, Protein from Yarrowia lipolytica)
- Nupm subunit (19 kDa, Protein from Yarrowia lipolytica)
- Nd6 subunit (nu6m) (20 kDa, Protein from Yarrowia lipolytica)
- Nb5m subunit (10 kDa, Protein from Yarrowia lipolytica)
- Mitochondrial nadh:ubiquinone oxidoreductase (963 MDa, Complex from Yarrowia lipolytica)
- Ni2m subunit (12 kDa, Protein from Yarrowia lipolytica)
- Nuem subunit (42 kDa, Protein from Yarrowia lipolytica)
- Nimm subunit (9 kDa, Protein from Yarrowia lipolytica)
- 49-kda protein (nucm) (52 kDa, Protein from Yarrowia lipolytica)
- Nb4m subunit (14 kDa, Protein from Yarrowia lipolytica)
- Nb6m subunit (14 kDa, Protein from Yarrowia lipolytica)
- Numm subunit (15 kDa, Protein from Yarrowia lipolytica)
- Nuxm subunit (18 kDa, Protein from Yarrowia lipolytica)
- N7bm subunit (16 kDa, Protein from Yarrowia lipolytica)
- Zinc ion (65 Da, Ligand)
- Nuum subunit (3 kDa, Protein from Yarrowia lipolytica)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Psst subunit (nukm) (23 kDa, Protein from Yarrowia lipolytica)
- Nb8m subunit (11 kDa, Protein from Yarrowia lipolytica)
- Nipm subunit (10 kDa, Protein from Yarrowia lipolytica)
- Nufm subunit (16 kDa, Protein from Yarrowia lipolytica)
- 30-kda protein (nugm) (32 kDa, Protein from Yarrowia lipolytica)
- Ni9m subunit (7 kDa, Protein from Yarrowia lipolytica)
- Iron/sulfur cluster (351 Da, Ligand)
- Nujm subunit (20 kDa, Protein from Yarrowia lipolytica)
- Nunm subunit (7 kDa, Protein from Yarrowia lipolytica)
- Acpm1 subunit (12 kDa, Protein from Yarrowia lipolytica)
- Nebm subunit (5 kDa, Protein from Yarrowia lipolytica)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Cryo-EM structure of respiratory complex I from Yarrowia lipolytica under turnover
Parey K, Brandt U, Xie H, Mills DJ, Siegmund K, Vonck J, Kuehlbrandt W, Zickermann V
eLife (2018) 7 [ DOI: doi:10.7554/eLife.39213 Pubmed: 30277212 ]
Sample:
- Mitochondrial nadh:ubiquinone oxidoreductase (963 MDa, Complex from Yarrowia lipolytica)
Cryo-EM structure of a respiratory complex I assembly intermediate with NDUFAF2
Release date: Oct. 10, 2018
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6rfq
Q-score: 0.461
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6rfq
Q-score: 0.461
Parey K, Haapanen O, Sharma V, Kofeler H, Zullig T, Prinz S, Siegmund K, Wittig I, Mills DJ, Vonck J, Kuhlbrandt W, Zickermann V
Sci Adv (2019) 5 pp. eaax9484-eaax9484 [ Pubmed: 31844670 DOI: doi:10.1126/sciadv.aax9484 ]
Sample:
- Subunit nuam of nadh:ubiquinone oxidoreductase (complex i) (79 kDa, Protein from Yarrowia lipolytica)
- Subunit nucm of nadh:ubiquinone oxidoreductase (complex i) (52 kDa, Protein from Yarrowia lipolytica)
- Subunit nipm of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Yarrowia lipolytica)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Subunit nukm of nadh:ubiquinone oxidoreductase (complex i) (23 kDa, Protein from Yarrowia lipolytica)
- Subunit ni8m of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nb4m of protein nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Subunit nujm of nadh:ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Yarrowia lipolytica)
- Subunit nuvm of nadh:ubiquinone oxidoreductase (complex i) (7 kDa, Protein from Yarrowia lipolytica)
- Acyl carrier protein acpm1 of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Yarrowia lipolytica)
- Subunit nugm of nadh:ubiquinone oxidoreductase (complex i) (32 kDa, Protein from Yarrowia lipolytica)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit nu1m of nadh:ubiquinone oxidoreductase (complex i) (38 kDa, Protein from Yarrowia lipolytica)
- Subunit nesm of nadh:ubiquinone oxidoreductase (complex i) (28 kDa, Protein from Yarrowia lipolytica)
- Flavin mononucleotide (456 Da, Ligand)
- Subunit niam of nadh:ubiquinone oxidoreductase (complex i) (17 kDa, Protein from Yarrowia lipolytica)
- Subunit nupm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Acyl carrier protein acpm2 of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Subunit nufm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nuem of nadh:ubiquinone oxidoreductase (complex i) (42 kDa, Protein from Yarrowia lipolytica)
- 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine (758 Da, Ligand)
- Subunit nb8m of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Yarrowia lipolytica)
- Subunit nuhm of nadh:ubiquinone oxidoreductase (complex i) (27 kDa, Protein from Yarrowia lipolytica)
- Subunit nimm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nuxm of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Yarrowia lipolytica)
- Subunit ni2m of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Yarrowia lipolytica)
- Subunit n7bm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nunm of nadh:ubiquinone oxidoreductase (complex i) (13 kDa, Protein from Yarrowia lipolytica)
- Subunit nulm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nu6m of nadh:ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Yarrowia lipolytica)
- Subunit nuim of nadh:ubiquinone oxidoreductase (complex i) (25 kDa, Protein from Yarrowia lipolytica)
- Subunit ni9m of nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Phosphatidylinositol (887 Da, Ligand)
- Subunit nubm of nadh:ubiquinone oxidoreductase (complex i) (53 kDa, Protein from Yarrowia lipolytica)
- Subunit nidm of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Yarrowia lipolytica)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Subunit nu5m of nadh:ubiquinone oxidoreductase (complex i) (73 kDa, Protein from Yarrowia lipolytica)
- Subunit nuym of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Yarrowia lipolytica)
- Subunit nebm of nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Diundecyl phosphatidyl choline (622 Da, Ligand)
- Subunit nb2m of nadh:ubiquinone oxidoreductase (complex i) (6 kDa, Protein from Yarrowia lipolytica)
- Subunit nb6m of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Subunit nu2m of nadh:ubiquinone oxidoreductase (complex i) (53 kDa, Protein from Yarrowia lipolytica)
- Subunit nuzm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Subunit nu4m of nadh:ubiquinone oxidoreductase (complex i) (54 kDa, Protein from Yarrowia lipolytica)
- Subunit nu3m of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Subunit n7bml assembly factor (27 kDa, Protein from Yarrowia lipolytica)
- Subunit nuum of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Yarrowia lipolytica)
- Iron/sulfur cluster (351 Da, Ligand)
- Complex i assembly intermediate (Complex from Yarrowia lipolytica)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Cryo-EM structure of respiratory complex I from Yarrowia lipolytica at 3.2 A resolution
Release date: Oct. 10, 2018
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6rfr
Q-score: 0.506
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6rfr
Q-score: 0.506
Parey K, Haapanen O, Sharma V, Kofeler H, Zullig T, Prinz S, Siegmund K, Wittig I, Mills DJ, Vonck J, Kuhlbrandt W, Zickermann V
Sci Adv (2019) 5 pp. eaax9484-eaax9484 [ Pubmed: 31844670 DOI: doi:10.1126/sciadv.aax9484 ]
Sample:
- Subunit nuam of nadh:ubiquinone oxidoreductase (complex i) (79 kDa, Protein from Yarrowia lipolytica)
- Subunit nucm of nadh:ubiquinone oxidoreductase (complex i) (52 kDa, Protein from Yarrowia lipolytica)
- Subunit nipm of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Yarrowia lipolytica)
- Cardiolipin (1 kDa, Ligand)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Subunit nukm of nadh:ubiquinone oxidoreductase (complex i) (23 kDa, Protein from Yarrowia lipolytica)
- Subunit ni8m of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nb4m of protein nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Mitochondrial nadh:ubiquinone oxidoreductase (1 MDa, Complex from Yarrowia lipolytica)
- Subunit nujm of nadh:ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Yarrowia lipolytica)
- Subunit nuvm of nadh:ubiquinone oxidoreductase (complex i) (7 kDa, Protein from Yarrowia lipolytica)
- Acyl carrier protein acpm1 of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Yarrowia lipolytica)
- Subunit nugm of nadh:ubiquinone oxidoreductase (complex i) (32 kDa, Protein from Yarrowia lipolytica)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit nu1m of nadh:ubiquinone oxidoreductase (complex i) (38 kDa, Protein from Yarrowia lipolytica)
- Subunit nesm of nadh:ubiquinone oxidoreductase (complex i) (28 kDa, Protein from Yarrowia lipolytica)
- Flavin mononucleotide (456 Da, Ligand)
- Subunit niam of nadh:ubiquinone oxidoreductase (complex i) (17 kDa, Protein from Yarrowia lipolytica)
- Subunit nupm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Acyl carrier protein acpm2 of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Subunit nufm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nuem of nadh:ubiquinone oxidoreductase (complex i) (42 kDa, Protein from Yarrowia lipolytica)
- Ubiquinone-9 (795 Da, Ligand)
- Subunit numm of protein nadh:ubiquinone oxidoreductase (complex i) (15 kDa, Protein from Yarrowia lipolytica)
- 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine (758 Da, Ligand)
- Subunit nb8m of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Yarrowia lipolytica)
- Subunit nb5m of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Yarrowia lipolytica)
- Subunit nuhm of nadh:ubiquinone oxidoreductase (complex i) (27 kDa, Protein from Yarrowia lipolytica)
- Subunit nimm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit n7bm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nuxm of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Yarrowia lipolytica)
- Subunit ni2m of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Yarrowia lipolytica)
- Subunit nunm of nadh:ubiquinone oxidoreductase (complex i) (13 kDa, Protein from Yarrowia lipolytica)
- Subunit nulm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nu6m of nadh:ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Yarrowia lipolytica)
- Subunit nuim of nadh:ubiquinone oxidoreductase (complex i) (25 kDa, Protein from Yarrowia lipolytica)
- Subunit ni9m of nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Phosphatidylinositol (887 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Subunit nubm of nadh:ubiquinone oxidoreductase (complex i) (53 kDa, Protein from Yarrowia lipolytica)
- Subunit nidm of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Yarrowia lipolytica)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Subunit nu5m of nadh:ubiquinone oxidoreductase (complex i) (73 kDa, Protein from Yarrowia lipolytica)
- Subunit nuym of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Yarrowia lipolytica)
- Subunit nebm of nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Subunit nuum of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Diundecyl phosphatidyl choline (622 Da, Ligand)
- Subunit nb2m of nadh:ubiquinone oxidoreductase (complex i) (6 kDa, Protein from Yarrowia lipolytica)
- Subunit nb6m of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Subunit nu2m of nadh:ubiquinone oxidoreductase (complex i) (53 kDa, Protein from Yarrowia lipolytica)
- Subunit nuzm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Subunit nu4m of nadh:ubiquinone oxidoreductase (complex i) (54 kDa, Protein from Yarrowia lipolytica)
- Subunit nu3m of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Iron/sulfur cluster (351 Da, Ligand)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Cryo-EM structure of a respiratory complex I mutant lacking NDUFS4
Release date: Oct. 10, 2018
Resolution: 4.04 Å
EM Method: Single-particle
Fitted PDBs: 6rfs
Q-score: 0.342
Resolution: 4.04 Å
EM Method: Single-particle
Fitted PDBs: 6rfs
Q-score: 0.342
Parey K, Haapanen O, Sharma V, Kofeler H, Zullig T, Prinz S, Siegmund K, Wittig I, Mills DJ, Vonck J, Kuhlbrandt W, Zickermann V
Sci Adv (2019) 5 pp. eaax9484-eaax9484 [ Pubmed: 31844670 DOI: doi:10.1126/sciadv.aax9484 ]
Sample:
- Subunit nuam of nadh:ubiquinone oxidoreductase (complex i) (79 kDa, Protein from Yarrowia lipolytica)
- Subunit nucm of nadh:ubiquinone oxidoreductase (complex i) (52 kDa, Protein from Yarrowia lipolytica)
- Subunit nipm of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Yarrowia lipolytica)
- Subunit nukm of nadh:ubiquinone oxidoreductase (complex i) (23 kDa, Protein from Yarrowia lipolytica)
- Subunit ni8m of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nb4m of protein nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Mitochondrial nadh:ubiquinone oxidoreductase (1 MDa, Complex from Yarrowia lipolytica)
- Subunit nujm of nadh:ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Yarrowia lipolytica)
- Subunit numm of nadh:ubiquinone oxidoreductase (complex i) (15 kDa, Protein from Yarrowia lipolytica)
- Acyl carrier protein acpm1 of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Yarrowia lipolytica)
- Subunit nuvm of nadh:ubiquinone oxidoreductase (complex i) (7 kDa, Protein from Yarrowia lipolytica)
- Subunit nugm of nadh:ubiquinone oxidoreductase (complex i) (32 kDa, Protein from Yarrowia lipolytica)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit nu1m of nadh:ubiquinone oxidoreductase (complex i) (38 kDa, Protein from Yarrowia lipolytica)
- Subunit nesm of nadh:ubiquinone oxidoreductase (complex i) (28 kDa, Protein from Yarrowia lipolytica)
- Flavin mononucleotide (456 Da, Ligand)
- Subunit niam of nadh:ubiquinone oxidoreductase (complex i) (17 kDa, Protein from Yarrowia lipolytica)
- Subunit nupm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Acyl carrier protein acpm2 of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Subunit nufm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nuem of nadh:ubiquinone oxidoreductase (complex i) (42 kDa, Protein from Yarrowia lipolytica)
- Subunit nb8m of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Yarrowia lipolytica)
- Subunit nb5m of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Yarrowia lipolytica)
- Subunit nuhm of nadh:ubiquinone oxidoreductase (complex i) (27 kDa, Protein from Yarrowia lipolytica)
- Subunit nimm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit n7bm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nuxm of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Yarrowia lipolytica)
- Subunit ni2m of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Yarrowia lipolytica)
- Subunit nunm of nadh:ubiquinone oxidoreductase (complex i) (13 kDa, Protein from Yarrowia lipolytica)
- Subunit nulm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nu6m of nadh:ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Yarrowia lipolytica)
- Subunit nuim of nadh:ubiquinone oxidoreductase (complex i) (25 kDa, Protein from Yarrowia lipolytica)
- Subunit ni9m of nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Zinc ion (65 Da, Ligand)
- Subunit nubm of nadh:ubiquinone oxidoreductase (complex i) (53 kDa, Protein from Yarrowia lipolytica)
- Subunit nidm of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Yarrowia lipolytica)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Subunit nu5m of nadh:ubiquinone oxidoreductase (complex i) (73 kDa, Protein from Yarrowia lipolytica)
- Subunit nebm of nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Subunit nuum of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nb2m of nadh:ubiquinone oxidoreductase (complex i) (6 kDa, Protein from Yarrowia lipolytica)
- Subunit nb6m of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Subunit nu2m of nadh:ubiquinone oxidoreductase (complex i) (53 kDa, Protein from Yarrowia lipolytica)
- Subunit nuzm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Subunit nu4m of nadh:ubiquinone oxidoreductase (complex i) (54 kDa, Protein from Yarrowia lipolytica)
- Subunit nu3m of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Iron/sulfur cluster (351 Da, Ligand)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)