KS-AT di-domain of mycobacterial Pks13 with endogenous KS ligand bound
Resolution: 1.94 Å
EM Method: Single-particle
Fitted PDBs: 7uk4
Q-score: 0.628
Kim SK, Dickinson MS, Finer-Moore J, Guan Z, Kaake RM, Echeverria I, Chen J, Pulido EH, Sali A, Krogan NJ, Rosenberg OS, Stroud RM
Nat Struct Mol Biol (2023) 30 pp. 296-308 [ DOI: doi:10.1038/s41594-022-00918-0 Pubmed: 36782050 ]
- Water (18 Da, Ligand)
- Unknown ligand (312 Da, Ligand)
- Ketosynthase domain (Complex from Mycolicibacterium smegmatis MC2 155)
- Acyl transferase domain (Complex from Mycolicibacterium smegmatis MC2 155)
- Polyketide synthase pks13 (198 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Mycobacterial polyketide synthase 13 (Complex from Mycolicibacterium smegmatis MC2 155)
ACP1-KS-AT domains of mycobacterial Pks13
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8cuy
Q-score: 0.574
Kim SK, Dickinson MS, Finer-Moore J, Guan Z, Kaake RM, Echeverria I, Chen J, Pulido EH, Sali A, Krogan NJ, Rosenberg OS, Stroud RM
Nat Struct Mol Biol (2023) 30 pp. 296-308 [ DOI: doi:10.1038/s41594-022-00918-0 Pubmed: 36782050 ]
KS-AT domains of mycobacterial Pks13 with inward AT conformation
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8cuz
Q-score: 0.522
Kim SK, Dickinson MS, Finer-Moore J, Guan Z, Kaake RM, Echeverria I, Chen J, Pulido EH, Sali A, Krogan NJ, Rosenberg OS, Stroud RM
Nat Struct Mol Biol (2023) 30 pp. 296-308 [ DOI: doi:10.1038/s41594-022-00918-0 Pubmed: 36782050 ]
KS-AT domains of mycobacterial Pks13 with outward AT conformation
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8cv0
Q-score: 0.508
Kim SK, Dickinson MS, Finer-Moore J, Guan Z, Kaake RM, Echeverria I, Chen J, Pulido EH, Sali A, Krogan NJ, Rosenberg OS, Stroud RM
Nat Struct Mol Biol (2023) 30 pp. 296-308 [ DOI: doi:10.1038/s41594-022-00918-0 Pubmed: 36782050 ]
ACP1-KS-AT domains of mycobacterial Pks13
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8cv1
Q-score: 0.543
Kim SK, Dickinson MS, Finer-Moore J, Guan Z, Kaake RM, Echeverria I, Chen J, Pulido EH, Sali A, Krogan NJ, Rosenberg OS, Stroud RM
Nat Struct Mol Biol (2023) 30 pp. 296-308 [ DOI: doi:10.1038/s41594-022-00918-0 Pubmed: 36782050 ]
- Water (18 Da, Ligand)
- Unknown ligand (312 Da, Ligand)
- Polyketide synthase pks13 (194 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Mycobacterial polyketide synthase 13 (Complex from Mycolicibacterium smegmatis MC2 155)
Structure of human SetD3 methyl-transferase in complex with 2A protease from Coxsackievirus B3
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7lms
Q-score: 0.452
Peters CE, Schulze-Gahmen U, Eckhardt M, Jang GM, Xu J, Pulido EH, Bardine C, Craik CS, Ott M, Gozani O, Verba KA, Huttenhain R, Carette JE, Krogan NJ
Nat Commun (2022) 13 pp. 5282-5282 [ Pubmed: 36075902 DOI: doi:10.1038/s41467-022-32758-3 ]
- Actin-histidine n-methyltransferase (67 kDa, Protein from Homo sapiens)
- Protease 2a (16 kDa, Protein from Coxsackievirus B3 (strain Nancy))
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Ternary complex of coxsackievirus b3 2a protease and human setd3 methyltransferase (84 kDa, Complex from Coxsackievirus B3 (strain Nancy))