Identification, structure and agonist design of an androgen membrane receptor.
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 8x9s
Q-score: 0.506
Yang Z, Ping YQ, Wang MW, Zhang C, Zhou SH, Xi YT, Zhu KK, Ding W, Zhang QY, Song ZC, Zhao RJ, He ZL, Wang MX, Qi L, Ullmann C, Ricken A, Schoneberg T, Gan ZJ, Yu X, Xiao P, Yi F, Liebscher I, Sun JP
Cell (2025) [ Pubmed: 39884271 DOI: doi:10.1016/j.cell.2025.01.006 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Complex of gpr133 with agonist and g protein trime (Complex from Bos taurus)
- Adhesion g-protein coupled receptor d1 (65 kDa, Protein from Homo sapiens)
- 5-alpha-dihydrotestosterone (290 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Gs protein alpha subunit (41 kDa, Protein from Bos taurus)
Identification, structure and agonist design of an androgen membrane receptor
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 8x9t
Q-score: 0.524
Yang Z, Ping YQ, Wang MW, Zhang C, Zhou SH, Xi YT, Zhu KK, Ding W, Zhang QY, Song ZC, Zhao RJ, He ZL, Wang MX, Qi L, Ullmann C, Ricken A, Schoneberg T, Gan ZJ, Yu X, Xiao P, Yi F, Liebscher I, Sun JP
Cell (2025) [ Pubmed: 39884271 DOI: doi:10.1016/j.cell.2025.01.006 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Adhesion g-protein coupled receptor d1 (65 kDa, Protein from Homo sapiens)
- Methyl 3-[2-(2,4-dimethylphenoxy)ethanoylamino]-4-(4-ethylpiperazin-1-yl)benzoate (425 Da, Ligand)
- Complex of gpr133 with agonist and g protein trimer (Complex from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Scfv16 (28 kDa, Protein from synthetic construct)
- Gs protein alpha subunit (41 kDa, Protein from Bos taurus)
Identification, structure and agonist design of an androgen membrane receptor
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 8x9u
Q-score: 0.51
Yang Z, Ping YQ, Wang MW, Zhang C, Zhou SH, Xi YT, Zhu KK, Ding W, Zhang QY, Song ZC, Zhao RJ, He ZL, Wang MX, Qi L, Ullmann C, Ricken A, Schoneberg T, Gan ZJ, Yu X, Xiao P, Yi F, Liebscher I, Sun JP
Cell (2025) [ Pubmed: 39884271 DOI: doi:10.1016/j.cell.2025.01.006 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Complex of gpr133 with agonist and g protein trimer. (Complex from Rattus norvegicus)
- Adhesion g-protein coupled receptor d1 (65 kDa, Protein from Homo sapiens)
- (5s,8r,9s,10s,13s,14s,17s)-17-hydroxy-1,10,13-trimethyl-4,5,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one (302 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Scfv16 (28 kDa, Protein from synthetic construct)
- Gs protein alpha subunit (41 kDa, Protein from Bos taurus)
Identification, structure and agonist design of an androgen membrane receptor.
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 9iv1
Q-score: 0.478
Yang Z, Ping YQ, Wang MW, Zhang C, Zhou SH, Xi YT, Zhu KK, Ding W, Zhang QY, Song ZC, Zhao RJ, He ZL, Wang MX, Qi L, Ullmann C, Ricken A, Schoneberg T, Gan ZJ, Yu X, Xiao P, Yi F, Liebscher I, Sun JP
Cell (2025) [ Pubmed: 39884271 DOI: doi:10.1016/j.cell.2025.01.006 ]
- Adhesion g-protein coupled receptor d1 (34 kDa, Protein from Homo sapiens)
- 5-alpha-dihydrotestosterone (290 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (41 kDa, Protein from Homo sapiens)
- Complex of gpr133 with agonist and g protein trime (Complex from Homo sapiens)
- Scfv16 (28 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
Identification, structure and agonist design of an androgen membrane receptor.
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 9iv2
Q-score: 0.503
Yang Z, Ping YQ, Wang MW, Zhang C, Zhou SH, Xi YT, Zhu KK, Ding W, Zhang QY, Song ZC, Zhao RJ, He ZL, Wang MX, Qi L, Ullmann C, Ricken A, Schoneberg T, Gan ZJ, Yu X, Xiao P, Yi F, Liebscher I, Sun JP
Cell (2025) [ Pubmed: 39884271 DOI: doi:10.1016/j.cell.2025.01.006 ]
- Adhesion g-protein coupled receptor d1 (65 kDa, Protein from Homo sapiens)
- Gs protein alpha subunit (41 kDa, Protein from Homo sapiens)
- 5-alpha-dihydrotestosterone (290 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Complex of gpr133 with agonist and g protein trime (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
Cryo-EM structure of chitin synthase
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8k52
Q-score: 0.456
Niu S, Qi L, Zhang X, He D, Li P, Wang H, Bi Y
Int J Mol Sci (2024) 25 [ Pubmed: 39519219 DOI: doi:10.3390/ijms252111667 ]
- Uridine-5'-diphosphate (404 Da, Ligand)
- Chitin synthase (104 kDa, Protein from Phytophthora sojae strain P6497)
- Manganese (ii) ion (54 Da, Ligand)
- A membrane-integrated glycosyltransferase that transfers glcnac from udp-glcnac to a growing chitin chain (103 MDa, Complex from Phytophthora sojae)
Cryo-EM structure of chitin synthase
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8z0o
Q-score: 0.486
Niu S, Qi L, Zhang X, He D, Li P, Wang H, Bi Y
Int J Mol Sci (2024) 25 [ Pubmed: 39519219 DOI: doi:10.3390/ijms252111667 ]
- Uridine-5'-diphosphate (404 Da, Ligand)
- Chitin synthase (104 kDa, Protein from Phytophthora sojae strain P6497)
- Manganese (ii) ion (54 Da, Ligand)
- A membrane-integrated glycosyltransferase that transfers glcnac from udp-glcnac to a growing chitin chain (103 MDa, Complex from Phytophthora sojae strain P6497)
The self-assembled nanotube of CPC46A/Q70C
Resolution: 3.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 8y3n
Q-score: 0.464
Yang M, Rao G, Li L, Qi L, Ma C, Zhang H, Gong J, Wei B, Zhang XE, Chen G, Cao S, Li F
ACS Nano (2024) 18 pp. 13755-13767 [ Pubmed: 38752610 DOI: doi:10.1021/acsnano.4c01969 ]
- Capsid protein (13 kDa, Protein from Emesvirus zinderi)
- Cpc46a/q70c (Complex from Emesvirus zinderi)
The self-assembled nanotube of CPC46A/Q70H
Resolution: 2.61 Å
EM Method: Helical reconstruction
Fitted PDBs: 8y3t
Q-score: 0.616
Yang M, Rao G, Li L, Qi L, Ma C, Zhang H, Gong J, Wei B, Zhang XE, Chen G, Cao S, Li F
ACS Nano (2024) 18 pp. 13755-13767 [ Pubmed: 38752610 DOI: doi:10.1021/acsnano.4c01969 ]
- Cpc46a/q70h (Complex from Emesvirus zinderi)
- Capsid protein (13 kDa, Protein from Emesvirus zinderi)
The self-assembled nanotube of CPC46A/Q70V
Resolution: 3.46 Å
EM Method: Helical reconstruction
Fitted PDBs: 8y3v
Q-score: 0.523
Yang M, Rao G, Li L, Qi L, Ma C, Zhang H, Gong J, Wei B, Zhang XE, Chen G, Cao S, Li F
ACS Nano (2024) 18 pp. 13755-13767 [ Pubmed: 38752610 DOI: doi:10.1021/acsnano.4c01969 ]
- Capsid protein (13 kDa, Protein from Emesvirus zinderi)
- Cpc46a/q70v (Complex from Emesvirus zinderi)