Cryo-EM structure of expanded coxsackievirus A16 empty particle after incubation with 8C4 antibody
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 7yv2
Q-score: 0.464
Zhang C, Liu C, Shi J, Wang Y, Xu C, Ye X, Liu Q, Li X, Qiao W, Yin Y, Cong Y, Huang Z
Nat Commun (2022) 13 pp. 7854-7854 [ DOI: doi:10.1038/s41467-022-35575-w Pubmed: 36543790 ]
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Cryo-em structure of expanded coxsackievirus a16 empty particle after incubation with 8c4 antibody (Complex from Coxsackievirus A16)
Cryo-EM structure of expanded coxsackievirus A16 empty particle in complex with antibody 9B5
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7yv7
Q-score: 0.274
Zhang C, Liu C, Shi J, Wang Y, Xu C, Ye X, Liu Q, Li X, Qiao W, Yin Y, Cong Y, Huang Z
Nat Commun (2022) 13 pp. 7854-7854 [ DOI: doi:10.1038/s41467-022-35575-w Pubmed: 36543790 ]
- The light chain of antibody 9b5 (23 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- The heavy chain of antibody 9b5 (23 kDa, Protein from Coxsackievirus A16)
- Cryo-em structure of expanded coxsackievirus a16 empty particle in complex with antibody 9b5 (Complex from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
Cryo-EM structure of compact CA16 empty particle in complex with a neutralizing antibody 8C4
Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 7yrf
Q-score: 0.433
Zhang C, Liu C, Shi J, Wang Y, Xu C, Ye X, Liu Q, Li X, Qiao W, Yin Y, Cong Y, Huang Z
Nat Commun (2022) 13 pp. 7854-7854 [ DOI: doi:10.1038/s41467-022-35575-w Pubmed: 36543790 ]
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Genome polyprotein (25 kDa, Protein from Coxsackievirus A16)
- Light chain of chain (23 kDa, Protein from Coxsackievirus A16)
- The heavy chain of the antibody 8c4 (22 kDa, Protein from Coxsackievirus A16)
- Sphingosine (299 Da, Ligand)
- Genome polyprotein (33 kDa, Protein from Coxsackievirus A16)
- Cryo-em structure of compact ca16 empty particle in complex with a neutralizing antibody 8c4 (Complex from Coxsackievirus A16)
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 7yrh
Q-score: 0.405
Zhang C, Liu C, Shi J, Wang Y, Xu C, Ye X, Liu Q, Li X, Qiao W, Yin Y, Cong Y, Huang Z
Nat Commun (2022) 13 pp. 7854-7854 [ DOI: doi:10.1038/s41467-022-35575-w Pubmed: 36543790 ]
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Cryo-em structure of compact coxsackievirus a16 empty particle in complex with a neutralizing antibody 9b5 (Complex from Coxsackievirus A16)
- The light chain of the antibody 9b5 (23 kDa, Protein from Coxsackievirus A16)
- Sphingosine (299 Da, Ligand)
- Genome polyprotein (33 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- The heavy chain of the antibody 9b5 (23 kDa, Protein from Coxsackievirus A16)
The structure of coxsackievirus A16 mature virion in complex with Fab 8C4
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 7y7m
Q-score: 0.513
Zhang C, Liu C, Shi J, Wang Y, Xu C, Ye X, Liu Q, Li X, Qiao W, Yin Y, Cong Y, Huang Z
Nat Commun (2022) 13 pp. 7854-7854 [ DOI: doi:10.1038/s41467-022-35575-w Pubmed: 36543790 ]
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- The light chain of fab 8c4 (23 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- Sphingosine (299 Da, Ligand)
- Cryo-em structure of coxsackievirus a16 mature virus in complex with a neutralizing antibody 8c4 (Complex from Coxsackievirus A16)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus A16)
- The heavy chain of fab 8c4 (22 kDa, Protein from Coxsackievirus A16)
Cryo-EM structure of Coxsackievirus A16 in complex with a neutralizing antibody 9B5
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7yms
Q-score: 0.424
Zhang C, Liu C, Shi J, Wang Y, Xu C, Ye X, Liu Q, Li X, Qiao W, Yin Y, Cong Y, Huang Z
Nat Commun (2022) 13 pp. 7854-7854 [ DOI: doi:10.1038/s41467-022-35575-w Pubmed: 36543790 ]
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- Cryo-em structure of coxsackievirus a16 in complex with a neutralizing antibody 9b5 (Complex from Coxsackievirus A16)
- The heavy chain of fab 9b5 (23 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus A16)
- The light chain of fab 9b5 (23 kDa, Protein from Coxsackievirus A16)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7dcc
Q-score: 0.137
Zhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z
Nat Commun (2021) 12 pp. 264-264 [ Pubmed: 33431876 DOI: doi:10.1038/s41467-020-20465-w ]
- Spike glycoprotein (140 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sarc-cov2-s protein (Complex)
- 3c1 fab with a heavy chain and a light chain (Complex from Severe acute respiratory syndrome coronavirus 2)
- The heavy chain of 3c1 fab (24 kDa, Protein from Mus musculus)
- The light chain of 3c1 fab (23 kDa, Protein from Mus musculus)
- Complex of sarc-cov2-s protein with 3c1 fab, all the three rbds are in the up conformation and each of them associates with a 3c1 fab (Complex from Mus musculus)
S-3C1-F3a structure, two RBDs are up and one RBD is down, each RBD binds with a 3C1 fab.
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 7dcx
Q-score: 0.087
Zhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z
Nat Commun (2021) 12 pp. 264-264 [ Pubmed: 33431876 DOI: doi:10.1038/s41467-020-20465-w ]
- Complex of sars-cov2-s protein with 3c1 fab, two rbds are up and one rbd is down (Complex from Mus musculus)
- Spike glycoprotein (140 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 3c1 fab with a heavy chain and a light chain (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov2-s protein (Complex)
- The light chain of 3c1 fab (23 kDa, Protein from Mus musculus)
- The heavy chain of 3c1 fab that binds with the up rbd (24 kDa, Protein from Mus musculus)
S-3C1-F2 structure, two RBDs are up and one RBD is down, the two up RBD bind with a 3C1 fab.
Resolution: 5.6 Å
EM Method: Single-particle
Fitted PDBs: 7dd2
Q-score: 0.1
Zhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z
Nat Commun (2021) 12 pp. 264-264 [ Pubmed: 33431876 DOI: doi:10.1038/s41467-020-20465-w ]
- Spike glycoprotein (140 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov2-s protein (Complex from Mus musculus)
- 3c1 fab with a heavy chain and a light chain (Complex)
- The heavy chain of 3c1 fab (24 kDa, Protein from Mus musculus)
- Complex of sars-cov2-s protein with 3c1 fab, two rbds are up and one rbd is down, only the two up rbds bind with a 3c1 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- The light chain of 3c1 fab (23 kDa, Protein from Mus musculus)
S-3C1-F1 structure, one RBD is up and two RBDs are down, the up RBD binds with a 3C1 fab
Resolution: 7.5 Å
EM Method: Single-particle
Fitted PDBs: 7dd8
Q-score: 0.081
Zhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z
Nat Commun (2021) 12 pp. 264-264 [ Pubmed: 33431876 DOI: doi:10.1038/s41467-020-20465-w ]
- Spike glycoprotein (140 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- The light chain of 3c1 chain (23 kDa, Protein from Mus musculus)
- 3c1 fab with a heavy chain and a light chain (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov2-s protein (Complex)
- The heavy chain of 3c1 fab (24 kDa, Protein from Mus musculus)
- Complex of sars-cov2-s protein with 3c1 fab, one rbd is up and two rbds are down, the up rbd binds with a 3c1 fab (Complex from Mus musculus)