Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 8gbr
Q-score: 0.513
Nguyen BA, Singh V, Afrin S, Singh P, Pekala M, Ahmed Y, Pedretti R, Canepa J, Lemoff A, Kluve-Beckerman B, Wydorski PM, Chhapra F, Saelices L
Commun Biol (2024) 7 pp. 905-905 [ Pubmed: 39068302 DOI: doi:10.1038/s42003-024-06588-6 ]
Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
Resolution: 3.28 Å
EM Method: Helical reconstruction
Fitted PDBs: 8g9r
Q-score: 0.038
Nguyen BA, Singh V, Afrin S, Singh P, Pekala M, Ahmed Y, Pedretti R, Canepa J, Lemoff A, Kluve-Beckerman B, Wydorski PM, Chhapra F, Saelices L
Commun Biol (2024) 7 pp. 905-905 [ Pubmed: 39068302 DOI: doi:10.1038/s42003-024-06588-6 ]
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 8tdn
Q-score: 0.559
Nguyen BA, Singh V, Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P, Pekala M, Cabrera Hernandez LO, Kumar S, Lemoff A, Gonzalez-Prieto R, Sawaya MR, Eisenberg DS, Benson MD, Saelices L
Nat Commun (2024) 15 pp. 581-581 [ Pubmed: 38233397 DOI: doi:10.1038/s41467-024-44820-3 ]
- Transthyretin (15 kDa, Protein from Homo sapiens)
- Transthyretin fibrils extracted from patient heart. (Complex from Homo sapiens)
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 8tdo
Q-score: 0.546
Nguyen BA, Singh V, Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P, Pekala M, Cabrera Hernandez LO, Kumar S, Lemoff A, Gonzalez-Prieto R, Sawaya MR, Eisenberg DS, Benson MD, Saelices L
Nat Commun (2024) 15 pp. 581-581 [ Pubmed: 38233397 DOI: doi:10.1038/s41467-024-44820-3 ]
- Transthyretin (15 kDa, Protein from Homo sapiens)
- Transthyretin fibrils extracted from patient heart. (Complex from Homo sapiens)
Cryo-EM structure of serine 87 O-GlcNAc-modified alpha-synuclein fibrils
Resolution: 4.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 8gf7
Q-score: 0.356
Balana AT, Mahul-Mellier AL, Nguyen BA, Horvath M, Javed A, Hard ER, Jasiqi Y, Singh P, Afrin S, Pedretti R, Singh V, Lee VM, Luk KC, Saelices L, Lashuel HA, Pratt MR
Nat Chem Biol (2024) 20 pp. 646-655 [ DOI: doi:10.1038/s41589-024-01551-2 Pubmed: 38347213 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Alpha-synuclein (8 kDa, Protein from Homo sapiens)
- Alpha-synuclein fibrils (Complex from Homo sapiens)
Cardiac amyloid fibrils extracted from a variant ATTR I84S amyloidosis patient
Resolution: 3.47 Å
EM Method: Helical reconstruction
Fitted PDBs: 8e7e
Q-score: -0.011
Nguyen BA, Singh V, Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P, Pekala M, Cabrera Hernandez LO, Kumar S, Lemoff A, Gonzalez-Prieto R, Sawaya MR, Eisenberg DS, Benson MD, Saelices L
Nat Commun (2024) 15 pp. 581- [ DOI: doi:10.1038/s41467-024-44820-3 ]
Cardiac amyloid fibrils extracted from a variant ATTR P24S amyloidosis patient
Resolution: 3.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 8e7i
Q-score: -0.025
To Be Published
Cardiac amyloid fibrils extracted from a variant ATTR I84S amyloidosis patient (2).
Resolution: 3.9 Å
EM Method: Helical reconstruction
Fitted PDBs: 8e7j
Q-score: 0.483
Nguyen BA, Singh V, Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P, Pekala M, Cabrera Hernandez LO, Kumar S, Lemoff A, Gonzalez-Prieto R, Sawaya MR, Eisenberg DS, Benson MD, Saelices L
Nat Commun (2024) 15 pp. 581-581 [ Pubmed: 38233397 DOI: doi:10.1038/s41467-024-44820-3 ]
Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
Resolution: 3.43 Å
EM Method: Helical reconstruction
Fitted PDBs: 8e7h
Q-score: 0.471
Nguyen BA, Singh V, Afrin S, Singh P, Pekala M, Ahmed Y, Pedretti R, Canepa J, Lemoff A, Kluve-Beckerman B, Wydorski PM, Chhapra F, Saelices L
Commun Biol (2024) 7 pp. 905- [ DOI: doi:10.1038/s42003-024-06588-6 ]
Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
Resolution: 3.31 Å
EM Method: Helical reconstruction
Fitted PDBs: 8e7d
Q-score: 0.507
Nguyen BA, Singh V, Afrin S, Singh P, Pekala M, Ahmed Y, Pedretti R, Canepa J, Lemoff A, Kluve-Beckerman B, Wydorski PM, Chhapra F, Saelices L
Commun Biol (2024) 7 pp. 905- [ DOI: doi:10.1038/s42003-024-06588-6 ]