Structure of the TSC:WIPI3 lysosomal recruitment complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9ce3
Q-score: 0.382
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Isoform 4 of tuberin (199 kDa, Protein from Homo sapiens)
- Tsc:wipi3 lysosomal recruitment complex (composite map) (733 kDa, Complex from Homo sapiens)
- Wd repeat domain phosphoinositide-interacting protein 3 (35 kDa, Protein from Homo sapiens)
- Unknown fragment (1 kDa, Protein from Homo sapiens)
- Hamartin (133 kDa, Protein from Homo sapiens)
- Tbc1 domain family member 7 (35 kDa, Protein from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (consensus reconstruction)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (focused reconstruction; core)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (focused reconstruction; TSC1 N-terminus)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (focused reconstruction; TBC1D7)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (focused reconstruction; TBC1D7/TSC2)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (focused reconstruction; WIPI3)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (focused reconstruction; WIPI3 TSC2)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)
Acinetobacter baumannii Tse15 Rhs effector, toxin cleavage mutant (D1369N, D1391N)
Resolution: 1.77 Å
EM Method: Single-particle
Fitted PDBs: 8uxt
Q-score: 0.647
Hayes BK, Harper M, Venugopal H, Lewis JM, Wright A, Lee HC, Steele JR, Steer DL, Schittenhelm RB, Boyce JD, McGowan S
Nat Commun (2024) 15 pp. 8709-8709 [ DOI: doi:10.1038/s41467-024-52950-x Pubmed: 39379370 ]
- Tse15 (181 kDa, Protein from Acinetobacter baumannii AB307-0294)
- Recombinant tse15(d1369n, d1391n) protein (183 kDa, Cellular component from Acinetobacter baumannii AB307-0294)
Acinetobacter baumannii Tse15 Rhs effector
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 8uy4
Q-score: 0.457
Hayes BK, Harper M, Venugopal H, Lewis JM, Wright A, Lee HC, Steele JR, Steer DL, Schittenhelm RB, Boyce JD, McGowan S
Nat Commun (2024) 15 pp. 8709-8709 [ DOI: doi:10.1038/s41467-024-52950-x Pubmed: 39379370 ]
- Tse15 toxin peptide (polyunk) (2 kDa, Protein from Acinetobacter baumannii AB307-0294)
- Recombinant tse15 (183 kDa, Cellular component from Acinetobacter baumannii AB307-0294)
- Tse15 (182 kDa, Protein from Acinetobacter baumannii AB307-0294)
- Tse15 toxin peptide (polyunk) (3 kDa, Protein from Acinetobacter baumannii AB307-0294)
- Tse15 toxin peptide (polyunk) (2 kDa, Protein from Acinetobacter baumannii AB307-0294)
- Tse15 toxin peptide (polyunk) (954 Da, Protein from Acinetobacter baumannii AB307-0294)