3D reconstruction of the apical complex of Plasmodium falciparum (3D7) free merozoite
Sun SY, Segev-Zarko L-, Pintilie GD, Kim CY, Staggers SR, Schmid MF, Egan ES, Chiu W, Boothroyd JC
Mbio (2024) 15 pp. e0286423-e0286423 [ DOI: doi:10.1128/mbio.02864-23 Pubmed: 38456679 ]
3D reconstruction of the apical complex of Plasmodium falciparum (3D7) free merozoite
Sun SY, Segev-Zarko L-, Pintilie GD, Kim CY, Staggers SR, Schmid MF, Egan ES, Chiu W, Boothroyd JC
Mbio (2024) 15 pp. e0286423-e0286423 [ DOI: doi:10.1128/mbio.02864-23 Pubmed: 38456679 ]
3D Reconstruction of Plasmodium falciparum (3D7) free merozoite
Sun SY, Segev-Zarko L-, Pintilie GD, Kim CY, Staggers SR, Schmid MF, Egan ES, Chiu W, Boothroyd JC
Mbio (2024) 15 pp. e0286423-e0286423 [ DOI: doi:10.1128/mbio.02864-23 Pubmed: 38456679 ]
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8u26
Q-score: 0.572
Nat Methods (2024) 21 pp. 37-40 [ Pubmed: 37973972 DOI: doi:10.1038/s41592-023-02082-9 ]
- Nanobody 35 (15 kDa, Protein from Lama glama)
- Substance p bound to active human neurokinin 1 receptor in complex with minigs399 (141 kDa, Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Homo sapiens)
- Substance-p receptor (47 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Protachykinin-1 (1 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8u28
Q-score: 0.464
Nat Methods (2024) 21 pp. 37-40 [ Pubmed: 37973972 DOI: doi:10.1038/s41592-023-02082-9 ]
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8u2c
Q-score: 0.534
Nat Methods (2024) 21 pp. 37-40 [ Pubmed: 37973972 DOI: doi:10.1038/s41592-023-02082-9 ]
- 5d3 fab light chain variable domain (23 kDa, Protein from Mus musculus)
- Inhibitor-bound abcg2 (Complex from Homo sapiens)
- Fab heavy chain constant domain (22 kDa, Protein from Homo sapiens)
- Broad substrate specificity atp-binding cassette transporter abcg2 (72 kDa, Protein from Homo sapiens)
- 5d3 fab heavy chain variable domain (23 kDa, Protein from Mus musculus)
- Fab light chain constant domain (22 kDa, Protein from Homo sapiens)
Plasmodium falciparum merozoites apical 2-ring units
Sun SY, Segev-Zarko L-, Pintilie GD, Kim CY, Staggers SR, Schmid MF, Egan ES, Chiu W, Boothroyd JC
Mbio (2024) pp. e0286423-e0286423 [ DOI: doi:10.1128/mbio.02864-23 Pubmed: 38456679 ]
Sun SY, Segev-Zarko L-, Pintilie GD, Kim CY, Staggers SR, Schmid MF, Egan ES, Chiu W, Boothroyd JC
Mbio (2024) pp. e0286423-e0286423 [ DOI: doi:10.1128/mbio.02864-23 Pubmed: 38456679 ]
CryoET tomogram of mitochondria in BACHD mouse model neuron
Wu GH, Smith-Geater C, Galaz-Montoya JG, Gu Y, Gupte SR, Aviner R, Mitchell PG, Hsu J, Miramontes R, Wang KQ, Geller NR, Hou C, Danita C, Joubert LM, Schmid MF, Yeung S, Frydman J, Mobley W, Wu C, Thompson LM, Chiu W
Nat Commun (2023) 14 pp. 692-692 [ Pubmed: 36754966 DOI: doi:10.1038/s41467-023-36096-w ]
- Bachd mouse model neuron (Cell from Muridae)
CryoET tomogram of BACHD mouse model neuron showing sheet aggregates
Wu GH, Smith-Geater C, Galaz-Montoya JG, Gu Y, Gupte SR, Aviner R, Mitchell PG, Hsu J, Miramontes R, Wang KQ, Geller NR, Hou C, Danita C, Joubert LM, Schmid MF, Yeung S, Frydman J, Mobley W, Wu C, Thompson LM, Chiu W
Nat Commun (2023) 14 pp. 692-692 [ Pubmed: 36754966 DOI: doi:10.1038/s41467-023-36096-w ]