Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6uet
Q-score: 0.343
Zhang K, Li S, Kappel K, Pintilie G, Su Z, Mou TC, Schmid MF, Das R, Chiu W
Nat Commun (2019) 10 pp. 5511-5511 [ DOI: doi:10.1038/s41467-019-13494-7 Pubmed: 31796736 ]
- Sam-bound sam-iv riboswitch (Complex from Helicobacter pylori)
- Rna (119-mer) (38 kDa, RNA from Mycobacterium sp. MCS)
- Sam-bound sam-iv riboswitch (40 kDa, Complex from Helicobacter pylori)
- S-adenosylmethionine (398 Da, Ligand)
Small conformation of ssRNA-bound CRISPR_Csm complex
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6nud
Q-score: 0.254
Guo M, Zhang K, Zhu Y, Pintilie GD, Guan X, Li S, Schmid MF, Ma Z, Chiu W, Huang Z
Cell Res (2019) 29 pp. 305-312 [ Pubmed: 30814678 DOI: doi:10.1038/s41422-019-0151-x ]
- Crispr type iii-associated ramp protein csm4 (33 kDa, Protein from Streptococcus thermophilus)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Crrna (22 kDa, RNA from Streptococcus thermophilus)
- Small conformation of ssrna-bound crispr_csm complex (Complex from Streptococcus thermophilus)
- Crispr system cms protein csm2 (14 kDa, Protein from Streptococcus thermophilus)
- Crispr system single-strand-specific deoxyribonuclease cas10/csm1 (subtype iii-a) (86 kDa, Protein from Streptococcus thermophilus)
- Target ssrna (15 kDa, RNA from Streptococcus thermophilus)
- Crispr type iii-associated ramp protein csm3 (24 kDa, Protein from Streptococcus thermophilus)
Small conformation of apo CRISPR_Csm complex
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6nue
Q-score: 0.305
Guo M, Zhang K, Zhu Y, Pintilie GD, Guan X, Li S, Schmid MF, Ma Z, Chiu W, Huang Z
Cell Res (2019) 29 pp. 305-312 [ Pubmed: 30814678 DOI: doi:10.1038/s41422-019-0151-x ]
- Small conformation of apo crispr_csm complex (Complex from Streptococcus thermophilus)
- Crispr type iii-associated ramp protein csm4 (33 kDa, Protein from Streptococcus thermophilus)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Crispr system cms protein csm2 (14 kDa, Protein from Streptococcus thermophilus)
- Crrna (22 kDa, RNA from Streptococcus thermophilus)
- Crispr system single-strand-specific deoxyribonuclease cas10/csm1 (subtype iii-a) (86 kDa, Protein from Streptococcus thermophilus)
- Crispr type iii-associated ramp protein csm3 (24 kDa, Protein from Streptococcus thermophilus)
Asymmetric structure of AcrAB-TolC tripartite multi drug efflux pump
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 5o66
Q-score: 0.24
Wang Z, Fan G, Hryc CF, Blaza JN, Serysheva II, Schmid MF, Chiu W, Luisi BF, Du D
eLife (2017) 6 [ DOI: doi:10.7554/eLife.24905 Pubmed: 28355133 ]
- 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile (526 Da, Ligand)
- Outer membrane protein tolc (53 kDa, Protein from Escherichia coli (strain K12))
- Multidrug efflux pump accessory protein acrz (5 kDa, Protein from Escherichia coli (strain K12))
- Multidrug efflux pump subunit acra (39 kDa, Protein from Escherichia coli (strain K12))
- Acrabz-tolc (Complex from Escherichia coli K12)
- Multidrug efflux pump subunit acrb (113 kDa, Protein from Escherichia coli (strain K12))
multi-drug efflux; membrane transport; RND superfamily; Drug resistance
Resolution: 6.5 Å
EM Method: Single-particle
Fitted PDBs: 5ng5
Q-score: 0.326
Wang Z, Fan G, Hryc CF, Blaza JN, Serysheva II, Schmid MF, Chiu W, Luisi BF, Du D
eLife (2017) 6 [ DOI: doi:10.7554/eLife.24905 Pubmed: 28355133 ]
- Multidrug efflux pump accessory protein acrz (5 kDa, Protein from Escherichia coli)
- Multidrug efflux pump subunit acrb (113 kDa, Protein from Escherichia coli)
- Acrabtolc in apo state (Complex from Escherichia coli)
- 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile (526 Da, Ligand)
- Multidrug efflux pump subunit acra (39 kDa, Protein from Escherichia coli)
- Outer membrane protein tolc (53 kDa, Protein from Escherichia coli)