Asymmetric structure of AcrAB-TolC tripartite multi drug efflux pump
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 5o66
Q-score: 0.24
Wang Z, Fan G, Hryc CF, Blaza JN, Serysheva II, Schmid MF, Chiu W, Luisi BF, Du D
eLife (2017) 6 [ DOI: doi:10.7554/eLife.24905 Pubmed: 28355133 ]
- 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile (526 Da, Ligand)
- Outer membrane protein tolc (53 kDa, Protein from Escherichia coli (strain K12))
- Multidrug efflux pump accessory protein acrz (5 kDa, Protein from Escherichia coli (strain K12))
- Multidrug efflux pump subunit acra (39 kDa, Protein from Escherichia coli (strain K12))
- Acrabz-tolc (Complex from Escherichia coli K12)
- Multidrug efflux pump subunit acrb (113 kDa, Protein from Escherichia coli (strain K12))
multi-drug efflux; membrane transport; RND superfamily; Drug resistance
Resolution: 6.5 Å
EM Method: Single-particle
Fitted PDBs: 5ng5
Q-score: 0.326
Wang Z, Fan G, Hryc CF, Blaza JN, Serysheva II, Schmid MF, Chiu W, Luisi BF, Du D
eLife (2017) 6 [ DOI: doi:10.7554/eLife.24905 Pubmed: 28355133 ]
- Multidrug efflux pump accessory protein acrz (5 kDa, Protein from Escherichia coli)
- Multidrug efflux pump subunit acrb (113 kDa, Protein from Escherichia coli)
- Acrabtolc in apo state (Complex from Escherichia coli)
- 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile (526 Da, Ligand)
- Multidrug efflux pump subunit acra (39 kDa, Protein from Escherichia coli)
- Outer membrane protein tolc (53 kDa, Protein from Escherichia coli)
multi-drug efflux; membrane transport; RND superfamily; Drug resistance
Resolution: 6.5 Å
EM Method: Single-particle
Fitted PDBs: 5v5s
Q-score: 0.193
Wang Z, Fan G, Hryc CF, Blaza JN, Serysheva II, Schmid MF, Chiu W, Luisi BF, Du D
eLife (2017) 6 [ DOI: doi:10.7554/eLife.24905 Pubmed: 28355133 ]
- Multidrug efflux pump subunit acrb (113 kDa, Protein from Escherichia coli )
- Multidrug efflux pump subunit acra (42 kDa, Protein from Escherichia coli)
- Acrabtolc in apo state (Complex from Escherichia coli)
- Outer membrane protein tolc (48 kDa, Protein from Escherichia coli)
Bacteriophage P22 mature virion capsid protein
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 5uu5
Q-score: 0.548
Hryc CF, Chen DH, Afonine PV, Jakana J, Wang Z, Haase-Pettingell C, Jiang W, Adams PD, King JA, Schmid MF, Chiu W
PNAS (2017) 114 pp. 3103-3108 [ DOI: doi:10.1073/pnas.1621152114 Pubmed: 28270620 ]
- Major capsid protein (46 kDa, Protein from Salmonella phage P22)
- Enterobacteria phage p22 (327 MDa, Virus from Enterobacteria phage P22)
Bacteriophage P22 mature virion capsid protein
Chen DH, Afonine PV, Jakana J, Wang Z, Haase-Pettingell C, Jiang W, Adams PD, King JA, Schmid MF, Chiu W
Proc. Natl. Acad. Sci. U.S.A. (2017) [ Pubmed: 28270620 DOI: 10.1073/pnas.1621152114 ]
Image sets:
Full virus map of Brome Mosaic Virus
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 3j7l, 3j7m, 3j7n
Q-score: 0.41633335
Wang Z, Hryc CF, Bammes B, Afonine PV, Jakana J, Chen DH, Liu X, Baker ML, Kao C, Ludtke SJ, Schmid MF, Adams PD, Chiu W
Nat Commun (2014) 5 pp. 4808-4808 [ Pubmed: 25185801 DOI: doi:10.1038/ncomms5808 ]
- Brome mosaic virus (Virus from Brome mosaic virus)
- Brome mosaic virus (4 MDa, Sample)