Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 6wjd
Q-score: 0.23
Chen X, Dorris Z, Shi D, Huang RK, Khant H, Fox T, de Val N, Williams D, Zhang P, Walters KJ
Structure (2020) 28 pp. 1206-1217.e4 [ Pubmed: 32783951 DOI: doi:10.1016/j.str.2020.07.011 ]
- 26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- 26s proteasome regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- 26s proteasome regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
- 26s proteasome complex subunit sem1 (8 kDa, Protein from Homo sapiens)
- 26s proteasome regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
- 26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
- 26s proteasome regulatory subunit 6b (47 kDa, Protein from Homo sapiens)
- Human 26s proteasome with non-cleavable m1-linked hexaubiquitin and e3 ubiquitin ligase e6ap/ube3a (Complex from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 3 (61 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from Homo sapiens)
Resolution: 5.7 Å
EM Method: Single-particle
Fitted PDBs: 6wjn
Q-score: 0.174
Chen X, Dorris Z, Shi D, Huang RK, Khant H, Fox T, de Val N, Williams D, Zhang P, Walters KJ
Structure (2020) 28 pp. 1206-1217.e4 [ Pubmed: 32783951 DOI: doi:10.1016/j.str.2020.07.011 ]
- Proteasome subunit alpha type-5 (25 kDa, Protein from Homo sapiens)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 7 (32 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (28 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 8 (30 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-6 (20 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 4 (20 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
- Sd-like state of human 26s proteasome with non-cleavable m1-linked hexaubiquitin and e3 ubiquitin ligase e6ap/ube3a (Complex from Homo sapiens)
- Proteasome subunit alpha type-6 (26 kDa, Protein from Homo sapiens)
- 26s proteasome regulatory subunit 6b (43 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 14 (32 kDa, Protein from Homo sapiens)
- 26s proteasome complex subunit sem1 (8 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (23 kDa, Protein from Homo sapiens)
- 26s proteasome regulatory subunit 6a (44 kDa, Protein from Homo sapiens)
- 26s proteasome regulatory subunit 4 (43 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 11 (42 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-1 (26 kDa, Protein from Homo sapiens)
- 26s proteasome regulatory subunit 10b (42 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 3 (54 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 6 (44 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (23 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 1 (101 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
- 26s proteasome regulatory subunit 7 (44 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-5 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-4 (23 kDa, Protein from Homo sapiens)
- 26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from Homo sapiens)
SA-like state of human 26S proteasome in complex with non-cleavable M1-linked hexaubiquitin
Chen X, Dorris Z, Shi D, Huang RK, Khant H, Fox T, de Val N, Williams D, Zhang P, Walters KJ
Structure (2020) 28 pp. 1206-1217.e4 [ Pubmed: 32783951 DOI: doi:10.1016/j.str.2020.07.011 ]
SD-like state of human 26S proteasome in complex with non-cleavable M1-linked hexaubiquitin
Chen X, Dorris Z, Shi D, Huang RK, Khant H, Fox T, de Val N, Williams D, Zhang P, Walters KJ
Structure (2020) 28 pp. 1206-1217.e4 [ Pubmed: 32783951 DOI: doi:10.1016/j.str.2020.07.011 ]
SA-like state of human 26S proteasome in complex with non-cleavable M1-linked hexaubiquitin
Chen X, Dorris Z, Shi D, Huang RK, Khant H, Fox T, de Val N, Williams D, Zhang P, Walters KJ
Structure (2020) 28 pp. 1206-1217.e4 [ Pubmed: 32783951 DOI: doi:10.1016/j.str.2020.07.011 ]
SD-like state of human 26S proteasome in complex with non-cleavable M1-linked hexaubiquitin
Chen X, Dorris Z, Shi D, Huang RK, Khant H, Fox T, de Val N, Williams D, Zhang P, Walters KJ
Structure (2020) 28 pp. 1206-1217.e4 [ Pubmed: 32783951 DOI: doi:10.1016/j.str.2020.07.011 ]
Chen X, Dorris Z, Shi D, Huang RK, Khant H, Fox T, de Val N, Williams D, Zhang P, Walters KJ
Structure (2020) 28 pp. 1206-1217.e4 [ Pubmed: 32783951 DOI: doi:10.1016/j.str.2020.07.011 ]