Structure of CXCR3 in the apo-state (Receptor focused map)
Resolution: 3.68 Å
EM Method: Single-particle
Fitted PDBs: 8xxy
Q-score: 0.372
Structure of CXCR3 in the apo-state (Full map)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8xxz
Q-score: 0.464
Sano FK, Saha S, Sharma S, Ganguly M, Shihoya W, Nureki O, Shukla AK, Banerjee R
To Be Published
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (27 kDa, Protein from Homo sapiens)
- Antibody fragment scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Apo-cxcr3-go complex (Complex from Homo sapiens)
- C-x-c chemokine receptor type 3 (46 kDa, Protein from Homo sapiens)
Structure of CXCR3 in complex with VUF10661 (Receptor-ligand focused map)
Resolution: 3.16 Å
EM Method: Single-particle
Fitted PDBs: 8xyi
Q-score: 0.489
Sano FK, Saha S, Sharma S, Ganguly M, Shihoya W, Nureki O, Shukla AK, Banerjee R
To Be Published
- Structure of cxcr3 in complex with vuf10661 (Complex from Homo sapiens)
- (3~{s})-~{n}-[(2~{s})-6-azanyl-1-(2,2-diphenylethylamino)-1-oxidanylidene-hexan-2-yl]-2-(4-oxidanylidene-4-phenyl-butanoyl)-3,4-dihydro-1~{h}-isoquinoline-3-carboxamide (644 Da, Ligand)
- C-x-c chemokine receptor type 3 (46 kDa, Protein from Homo sapiens)
Structure of CXCR3 in complex with VUF10661 and Go (Full map)
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8xyk
Q-score: 0.509
Sano FK, Saha S, Sharma S, Ganguly M, Shihoya W, Nureki O, Shukla AK, Banerjee R
To Be Published
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (27 kDa, Protein from Homo sapiens)
- Cxcr3 in complex with vuf10661 and go (Complex from Homo sapiens)
- Antibody fragment scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- (3~{s})-~{n}-[(2~{s})-6-azanyl-1-(2,2-diphenylethylamino)-1-oxidanylidene-hexan-2-yl]-2-(4-oxidanylidene-4-phenyl-butanoyl)-3,4-dihydro-1~{h}-isoquinoline-3-carboxamide (644 Da, Ligand)
- C-x-c chemokine receptor type 3 (46 kDa, Protein from Homo sapiens)
Structure of CXCR3 in complex with VUF11418 (Receptor-ligand focused map)
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8y0h
Q-score: 0.433
Structure of CXCR3 in complex with VUF11418 and Go (Full map)
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 8y0n
Q-score: 0.491
Sano FK, Saha S, Sharma S, Ganguly M, Shihoya W, Nureki O, Shukla AK, Banerjee R
To Be Published
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cxcr3 in complex with vuf11418 and go (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (27 kDa, Protein from Homo sapiens)
- Antibody fragment scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- [(1~{r},5~{s})-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl-[[4-(2-iodanylphenyl)phenyl]methyl]-dimethyl-azanium (472 Da, Ligand)
- C-x-c chemokine receptor type 3 (46 kDa, Protein from Homo sapiens)
Structure of CXCR2 bound to CXCL1 (CXCR2-CXCL1-Go Full map)
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 8xwv
Q-score: 0.486
Sano FK, Saha S, Sharma S, Ganguly M, Shihoya W, Nureki O, Shukla AK, Banerjee R
To Be Published
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (6 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (27 kDa, Protein from Homo sapiens)
- Growth-regulated alpha protein (7 kDa, Protein from Homo sapiens)
- C-x-c chemokine receptor type 2 in complex with c-x-c motif chemokine 1 and go (Complex from Homo sapiens)
- Antibody fragment scfv16 (27 kDa, Protein from Mus musculus)
- C-x-c chemokine receptor type 2 (46 kDa, Protein from Homo sapiens)
Structure of mouse C5a-human C5aR1-Go complex
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8jzp
Q-score: 0.438
Yadav MK, Yadav R, Maharana J, Sarma P, Banerjee R, Shukla AK, Gati C
To Be Published
- Antibody fragment scfv16 (26 kDa, Protein from Mus musculus)
- Antibody fragment - scfv16 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Complement c5a (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(o) subunit alpha (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (27 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Homo sapiens)
- Mouse c5a-human c5ar1-go complex (Complex)
- C5a anaphylatoxin chemotactic receptor 1 (45 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- C5a anaphylatoxin chemotactic receptor 1 (Complex from Homo sapiens)
- C5a anaphylatoxin (12 kDa, Protein from Mus musculus)
Structure of CXCR2 bound to CXCL2 (Ligand-receptor focused map)
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8xvu
Q-score: 0.522
Sano FK, Saha S, Sharma S, Ganguly M, Shihoya W, Nureki O, Shukla AK, Banerjee R
To Be Published
- C-x-c motif chemokine 2 (Complex)
- C-x-c chemokine receptor type 2 in complex with c-x-c motif chemokine 2 (Complex from Homo sapiens)
- C-x-c chemokine receptor type 2 (Complex from Homo sapiens)
- C-x-c chemokine receptor type 2 (46 kDa, Protein from Homo sapiens)
- C-x-c motif chemokine 2 (7 kDa, Protein from Homo sapiens)
Structure of CXCR2 bound to CXCL1 (Ligand-receptor focused map)
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8xwa
Q-score: 0.492
Sano FK, Saha S, Sharma S, Ganguly M, Shihoya W, Nureki O, Shukla AK, Banerjee R
To Be Published
- C-x-c chemokine receptor type 2 in complex with c-x-c motif chemokine 1 (Complex from Homo sapiens)
- Growth-regulated alpha protein (7 kDa, Protein from Homo sapiens)
- C-x-c chemokine receptor type 2 (Complex from Homo sapiens)
- C-x-c chemokine receptor type 2 (46 kDa, Protein from Homo sapiens)
- C-x-c motif chemokine 1 (Complex)