Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 8jps
Q-score: 0.353
Saha S, Khanppnavar B, Maharana J, Kim H, Carino CMC, Daly C, Houston S, Sharma S, Zaidi N, Dalal A, Mishra S, Ganguly M, Tiwari D, Kumari P, Jhingan GD, Yadav PN, Plouffe B, Inoue A, Chung KY, Banerjee R, Korkhov VM, Shukla AK
Cell (2024) 187 pp. 4751-4769.e25 [ Pubmed: 39089252 DOI: doi:10.1016/j.cell.2024.07.005 ]
- Duffy antigen receptor for chemokines (darc)/ackr1 in complex with the chemokine, ccl7 (Complex from Homo sapiens)
- Ccl7 (Complex)
- Atypical chemokine receptor 1 (28 kDa, Protein from Homo sapiens)
- C-c motif chemokine 7 (7 kDa, Protein from Homo sapiens)
- Duffy antigen receptor for chemokines (darc)/ackr1 (Complex)
Saha S, Khanppnavar B, Maharana J, Kim H, Carino CMC, Daly C, Houston S, Sharma S, Zaidi N, Dalal A, Mishra S, Ganguly M, Tiwari D, Kumari P, Jhingan GD, Yadav PN, Plouffe B, Inoue A, Chung KY, Banerjee R, Korkhov VM, Shukla AK
Cell (2024) 187 pp. 4751-4769.e25 [ Pubmed: 39089252 DOI: doi:10.1016/j.cell.2024.07.005 ]
Saha S, Khanppnavar B, Maharana J, Kim H, Carino CMC, Daly C, Houston S, Sharma S, Zaidi N, Dalal A, Mishra S, Ganguly M, Tiwari D, Kumari P, Jhingan GD, Yadav PN, Plouffe B, Inoue A, Chung KY, Banerjee R, Korkhov VM, Shukla AK
Cell (2024) 187 pp. 4751-4769.e25 [ Pubmed: 39089252 DOI: doi:10.1016/j.cell.2024.07.005 ]
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8go9
Q-score: 0.46
Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK
Science (2024) 383 pp. 101-108 [ DOI: doi:10.1126/science.adj3347 Pubmed: 38175886 ]
- Fab30 (Complex from Mus musculus)
- Peptide bound beta-arrestin2 in complex with fab30 (190 kDa, Complex)
- Fab30 heavy chain (25 kDa, Protein from Mus musculus)
- Atypical chemokine receptor 2 (Complex from Homo sapiens)
- Beta-arrestin-2 (47 kDa, Protein from Bos taurus)
- Beta-arrestin2 (Complex from Bos taurus)
- Fab30 light chain (23 kDa, Protein from Mus musculus)
- Atypical chemokine receptor 2 (2 kDa, Protein from Homo sapiens)
Structure of beta-arrestin2 in complex with M2Rpp
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8j8r
Q-score: 0.543
Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK
Science (2024) 383 pp. 101-108 [ DOI: doi:10.1126/science.adj3347 Pubmed: 38175886 ]
- Beta-arrestin2 in complex with m2rpp (Complex)
- Fab30 (Complex from Mus musculus)
- Fab30 heavy chain (25 kDa, Protein from Mus musculus)
- Beta-arrestin-2 (47 kDa, Protein from Bos taurus)
- Beta-arrestin2 (Complex from Bos taurus)
- Muscarinic acetylcholine receptor m2 (2 kDa, Protein from Homo sapiens)
- Fab30 light chain (23 kDa, Protein from Mus musculus)
- Muscarinic receptor m2r (Complex from Homo sapiens)
Structure of beta-arrestin2 in complex with D6Rpp (Local Refine)
Resolution: 3.22 Å
EM Method: Single-particle
Fitted PDBs: 8j8v
Q-score: 0.514
Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK
Science (2024) 383 pp. 101-108 [ DOI: doi:10.1126/science.adj3347 Pubmed: 38175886 ]
- Fab30 (Complex from Mus musculus)
- Fab30 heavy chain (25 kDa, Protein from Mus musculus)
- Atypical chemokine receptor 2 (Complex from Homo sapiens)
- Beta-arrestin-2 (47 kDa, Protein from Bos taurus)
- Beta-arrestin2 in complex with d6rpp (Complex)
- Beta-arrestin2 (Complex from Bos taurus)
- Fab30 light chain (23 kDa, Protein from Mus musculus)
- Atypical chemokine receptor 2 (2 kDa, Protein from Homo sapiens)
Structure of beta-arrestin1 in complex with D6Rpp
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8j8z
Q-score: 0.489
Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK
Science (2024) 383 pp. 101-108 [ DOI: doi:10.1126/science.adj3347 Pubmed: 38175886 ]
- Beta-arrestin1 in complex with d6rpp (Complex)
- Beta-arrestin-1 (47 kDa, Protein from Rattus norvegicus)
- Fab30 heavy chain (25 kDa, Protein from Mus musculus)
- Beta-arrestin-1 (Complex from Rattus norvegicus)
- Atypical chemokine receptor 2 (2 kDa, Protein from Homo sapiens)
- Fab30 heavy chain (Complex from Mus musculus)
- Fab30 light chain (Complex from Mus musculus)
- Fab30 light chain (23 kDa, Protein from Mus musculus)
- Phosphopeptide derived from the c-terminal tail of ackr2 (d6r) receptor (Complex from Homo sapiens)
Structure of Muscarinic receptor (M2R) in complex with beta-arrestin1 (Local refine, cross-linked)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8j97
Q-score: 0.456
Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK
Science (2024) 383 pp. 101-108 [ DOI: doi:10.1126/science.adj3347 Pubmed: 38175886 ]
- Fab30 (Complex from Mus musculus)
- Beta-arrestin1 (Complex from Bos taurus)
- Fab30 heavy chain (12 kDa, Protein from Mus musculus)
- Beta-arrestin-1 (39 kDa, Protein from Bos taurus)
- Muscarinic receptor (m2r) in complex with beta-arrestin1 (Complex)
- Fab30 light chain (11 kDa, Protein from Mus musculus)
- Muscarinic receptor m2r (Complex from Homo sapiens)
- Muscarinic acetylcholine receptor m2 (1 kDa, Protein from Homo sapiens)
Muscarinic receptor (M2R) in complex with beta-arrestin1 (Low resolution full map, Cross-linked)
Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK
Science (2024) 383 pp. 101-108 [ DOI: doi:10.1126/science.adj3347 Pubmed: 38175886 ]
Muscarinic receptor (M2R) in complex with beta-arrestin1 (Low resolution full map, non-crosslinked)
Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK
Science (2024) 383 pp. 101-108 [ DOI: doi:10.1126/science.adj3347 Pubmed: 38175886 ]