DmDcr-2/R2D2/LoqsPD with 50bp-dsRNA in Dimer state
Resolution: 3.72 Å
EM Method: Single-particle
Fitted PDBs: 8hf0
Q-score: 0.372
Deng T, Su S, Yuan X, He J, Huang Y, Ma J, Wang J
Nat Commun (2023) 14 pp. 5228-5228 [ Pubmed: 37633971 DOI: doi:10.1038/s41467-023-40919-1 ]
- Dmdcr-2/r2d2/loqspd with 50bp-dsrna in dimer state (300 kDa, Complex from Drosophila melanogaster)
- Ld06392p (35 kDa, Protein from Drosophila melanogaster)
- Dicer-2, isoform a (198 kDa, Protein from Drosophila melanogaster)
- Loquacious, isoform d (38 kDa, Protein from Drosophila melanogaster)
- Rna (52-mer) (16 kDa, RNA from Drosophila melanogaster)
DmDcr-2/R2D2/LoqsPD with 19bp-dsRNA in Trimer state
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8hf1
Q-score: 0.307
Deng T, Su S, Yuan X, He J, Huang Y, Ma J, Wang J
Nat Commun (2023) 14 pp. 5228-5228 [ Pubmed: 37633971 DOI: doi:10.1038/s41467-023-40919-1 ]
- Dicer-2, isoform a (197 kDa, Protein from Drosophila melanogaster)
- Loquacious, isoform d (2 kDa, Protein from Drosophila melanogaster)
- Dmdcr-2/r2d2/loqspd with 19bp-dsrna in trimer state (300 kDa, Complex from Drosophila melanogaster)
- Rna (5'-r(p*cp*cp*ap*ap*gp*up*cp*up*cp*up*u)-3') (3 kDa, RNA from Drosophila melanogaster)
- Ld06392p (14 kDa, Protein from Drosophila melanogaster)
- Rna (5'-r(p*gp*ap*gp*ap*cp*up*up*gp*g)-3') (2 kDa, RNA from Drosophila melanogaster)
Structure of Full-Length AsfvPrimPol in Apo-Form
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 8iqh
Q-score: 0.383
Shao Z, Su S, Yang J, Zhang W, Gao Y, Zhao X, Zhang Y, Shao Q, Cao C, Li H, Liu H, Zhang J, Lin J, Ma J, Gan J
Nucleic Acids Res (2023) 51 pp. 9475-9490 [ Pubmed: 37587714 DOI: doi:10.1093/nar/gkad677 ]
- Putative primase c962r (111 kDa, Protein from African swine fever virus BA71V)
- Full-length asfvprimpol alone (1 MDa, Complex from African swine fever virus BA71V)
Structure of Full-Length AsfvPrimPol in Complex-Form
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8iqi
Q-score: 0.393
Shao Z, Su S, Yang J, Zhang W, Gao Y, Zhao X, Zhang Y, Shao Q, Cao C, Li H, Liu H, Zhang J, Lin J, Ma J, Gan J
Nucleic Acids Res (2023) 51 pp. 9475-9490 [ Pubmed: 37587714 DOI: doi:10.1093/nar/gkad677 ]
- Dna (Complex)
- Putative primase c962r (111 kDa, Protein from African swine fever virus BA71V)
- Full-length asfvprimpol in complex with dna and amppnp (660 kDa, Complex)
- Full-length asfvprimpol (Complex from African swine fever virus BA71V)
- Dna (32-mer) (9 kDa, DNA from synthetic construct)
- Magnesium ion (24 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Human m6A-METTL associated complex (WTAP, VIRMA, ZC3H13, and HAKAI)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7vf2
Q-score: 0.484
Su S, Li S, Deng T, Gao M, Yin Y, Wu B, Peng C, Liu J, Ma J, Zhang K
Cell Res (2022) 32 pp. 982-994 [ Pubmed: 36167981 DOI: doi:10.1038/s41422-022-00725-8 ]
- Pre-mrna-splicing regulator wtap (44 kDa, Protein from Homo sapiens)
- Human m6a-mettl associated complex (300 kDa, Complex from Homo sapiens)
- Protein virilizer homolog (202 kDa, Protein from Homo sapiens)
- Zinc finger ccch domain-containing protein 13 (64 kDa, Protein from Homo sapiens)
Human m6A-METTL associated complex (WTAP, VIRMA, and HAKAI)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7vf5
Q-score: 0.448
Su S, Li S, Deng T, Gao M, Yin Y, Wu B, Peng C, Liu J, Ma J, Zhang K
Cell Res (2022) 32 pp. 982-994 [ Pubmed: 36167981 DOI: doi:10.1038/s41422-022-00725-8 ]
- Human m6a-mettl associated complex(hwv) (300 kDa, Complex from Homo sapiens)
- Pre-mrna-splicing regulator wtap (44 kDa, Protein from Homo sapiens)
- Protein virilizer homolog (202 kDa, Protein from Homo sapiens)
dmDicer2-LoqsPD-dsRNA Dimer status
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 7w0a
Q-score: 0.51
Su S, Wang J, Deng T, Yuan X, He J, Liu N, Li X, Huang Y, Wang HW, Ma J
Nature (2022) 607 pp. 399-406 [ Pubmed: 35768513 DOI: doi:10.1038/s41586-022-04911-x ]
- Dicer2-loqspd-dsrna complex at its initial binding state (Complex from Drosophila melanogaster)
- Rna (30-mer) (10 kDa, RNA from Drosophila melanogaster)
- Rna (32-mer) (10 kDa, RNA from Spodoptera frugiperda)
- Dicer-2, isoform a (198 kDa, Protein from Drosophila melanogaster)
- Loquacious, isoform d (38 kDa, Protein from Drosophila melanogaster)
Dicer2-LoqsPD complex at apo status
Resolution: 3.33 Å
EM Method: Single-particle
Fitted PDBs: 7w0b
Q-score: 0.339
Su S, Wang J, Deng T, Yuan X, He J, Liu N, Li X, Huang Y, Wang HW, Ma J
Nature (2022) 607 pp. 399-406 [ Pubmed: 35768513 DOI: doi:10.1038/s41586-022-04911-x ]
- Loquacious, isoform d (38 kDa, Protein from Drosophila melanogaster)
- Dicer2-loqspd complex at its apo status (Complex from Drosophila melanogaster)
- Dicer-2, isoform a (198 kDa, Protein from Drosophila melanogaster)