SARS-CoV-2 RBD + IMCAS-123 + IMCAS-72 Fab
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8xse
Q-score: 0.531
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ Pubmed: 38850530 DOI: doi:10.1016/j.celrep.2024.114338 ]
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Imcas-123 l chain (23 kDa, Protein from Homo sapiens)
- Imcas-72 l chain (23 kDa, Protein from Homo sapiens)
- Imcas-123 h chain (23 kDa, Protein from Homo sapiens)
- Imcas-72 h chain (24 kDa, Protein from Homo sapiens)
- Cryo-em structure of sars-cov-2 rbd + imcas-123 + imcas-72 fab (Complex)
- Sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Imcas-123 + imcas-72 fab (Complex from Homo sapiens)
SARS-CoV-2 RBD + IMCAS-364 + hACE2
Resolution: 2.16 Å
EM Method: Single-particle
Fitted PDBs: 8xsf
Q-score: 0.416
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ Pubmed: 38850530 DOI: doi:10.1016/j.celrep.2024.114338 ]
- Ace2 (Complex from Homo sapiens)
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Imcas-364 h chain (50 kDa, Protein from Homo sapiens)
- Imcas-364 (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cryo-em structure of sars-cov-2 rbd + imcas-364 + hace2 (global refinement) (Complex)
- Sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Imcas-364 l chain (23 kDa, Protein from Homo sapiens)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 Omicron BA.4 RBD + IMCAS-316 + ACE2
Resolution: 2.61 Å
EM Method: Single-particle
Fitted PDBs: 8xsj
Q-score: 0.453
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ Pubmed: 38850530 DOI: doi:10.1016/j.celrep.2024.114338 ]
- Imcas-316 h chain (24 kDa, Protein from Homo sapiens)
- Imcas-316 l chain (23 kDa, Protein from Homo sapiens)
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Cryo-em structure of sars-cov-2 omicron ba.4 rbd + imcas-316 + ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8xsl
Q-score: 0.359
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ Pubmed: 38850530 DOI: doi:10.1016/j.celrep.2024.114338 ]
- Cryo-em structure of sars-cov-2 spike + imcas-123 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Imcas-123 heavy chain (23 kDa, Protein from Homo sapiens)
- Imcas-123 light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)