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author:"Vazquez-Laslop N" AND xref_links:"interpro" AND xref_links:"cpx"
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Wild-type Escherichia coli ribosome with antibiotic radezolid

Release date: March 2, 2022
Resolution: 2.47 Å
EM Method: Single-particle
Fitted PDBs: 7s1j
Q-score: 0.552

Tsai K, Stojkovic V, Lee DJ, Young ID, Szal T, Klepacki D, Vazquez-Laslop N, Mankin AS, Fraser JS, Fujimori DG

Nat Struct Mol Biol (2022) 29 pp. 162-171 [ DOI: doi:10.1038/s41594-022-00723-9 Pubmed: 35165456 ]

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Cryo-EM structure of an Escherichia coli TnaC-ribosome complex stalled in response to L-tryptophan

Release date: Sept. 1, 2021
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7o19
Q-score: 0.555

van der Stel AX, Gordon ER, Sengupta A, Martinez AK, Klepacki D, Perry TN, Herrero Del Valle A, Vazquez-Laslop N, Sachs MS, Cruz-Vera LR, Innis CA

Nat Commun (2021) 12 pp. 5340-5340 [ DOI: doi:10.1038/s41467-021-25663-8 Pubmed: 34504068 ]

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Cryo-EM structure of an Escherichia coli TnaC(R23F)-ribosome complex stalled in response to L-tryptophan

Release date: Sept. 1, 2021
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7o1a
Q-score: 0.573

van der Stel AX, Gordon ER, Sengupta A, Martinez AK, Klepacki D, Perry TN, Herrero Del Valle A, Vazquez-Laslop N, Sachs MS, Cruz-Vera LR, Innis CA

Nat Commun (2021) 12 pp. 5340-5340 [ DOI: doi:10.1038/s41467-021-25663-8 Pubmed: 34504068 ]

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Cryo-EM structure of an Escherichia coli TnaC(R23F)-ribosome-RF2 complex stalled in response to L-tryptophan

Release date: Sept. 1, 2021
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7o1c
Q-score: 0.555

van der Stel AX, Gordon ER, Sengupta A, Martinez AK, Klepacki D, Perry TN, Herrero Del Valle A, Vazquez-Laslop N, Sachs MS, Cruz-Vera LR, Innis CA

Nat Commun (2021) 12 pp. 5340-5340 [ DOI: doi:10.1038/s41467-021-25663-8 Pubmed: 34504068 ]

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50S ribosomal subunit without free 5S rRNA and perturbed PTC

Release date: June 24, 2020
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6wnt
Q-score: 0.425

Huang S, Aleksashin NA, Loveland AB, Klepacki D, Reier K, Kefi A, Szal T, Remme J, Jaeger L, Vazquez-Laslop N, Korostelev AA, Mankin AS

Nat Commun (2020) 11 pp. 2900-2900 [ DOI: doi:10.1038/s41467-020-16694-8 Pubmed: 32518240 ]

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70S ribosome without free 5S rRNA and with a perturbed PTC

Release date: June 24, 2020
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6wnv
Q-score: 0.383

Huang S, Aleksashin NA, Loveland AB, Klepacki D, Reier K, Kefi A, Szal T, Remme J, Jaeger L, Vazquez-Laslop N, Korostelev AA, Mankin AS

Nat Commun (2020) 11 pp. 2900-2900 [ DOI: doi:10.1038/s41467-020-16694-8 Pubmed: 32518240 ]

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Active 70S ribosome without free 5S rRNA and bound with A- and P- tRNA

Release date: June 24, 2020
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6wnw
Q-score: 0.43

Huang S, Aleksashin NA, Loveland AB, Klepacki D, Reier K, Kefi A, Szal T, Remme J, Jaeger L, Vazquez-Laslop N, Korostelev AA, Mankin AS

Nat Commun (2020) 11 pp. 2900-2900 [ DOI: doi:10.1038/s41467-020-16694-8 Pubmed: 32518240 ]

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Cryo-EM structure of the proline-rich antimicrobial peptide Api137 bound to the terminating ribosome

Release date: July 26, 2017
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 5o2r
Q-score: 0.476

Florin T, Maracci C, Graf M, Karki P, Klepacki D, Berninghausen O, Beckmann R, Vazquez-Laslop N, Wilson DN, Rodnina MV, Mankin AS

Nat Struct Mol Biol (2017) 24 pp. 752-757 [ Pubmed: 28741611 DOI: doi:10.1038/nsmb.3439 ]

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