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Tissue biology and disease modelling

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Structural biology

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EMD-17989

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CS respirasome from murine liver

Release date: April 24, 2024
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8pw5
Q-score: 0.465

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 2 (25 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Cox7a2l protein (12 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Heme c (618 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Mus musculus)
Iron/sulfur cluster (351 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Cytochrome b-c1 complex subunit 9 (7 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7b, mitochondrial (9 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7a2, mitochondrial (9 kDa, Protein from Mus musculus)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 8a, mitochondrial (7 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6c (8 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Mus musculus)
Cytochrome b (43 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Sodium ion (22 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Protoporphyrin ix containing fe (616 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6a1, mitochondrial (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Copper (ii) ion (63 Da, Ligand)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Dinuclear copper ion (127 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 1 (56 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (19 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Tristearoylglycerol (891 Da, Ligand)
Cytochrome c oxidase subunit 3 (29 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Heme-a (852 Da, Ligand)
Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Mus musculus)
Sc respirasome from murine liver (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)

[Show more]

EMD-17990

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C respirasome from murine liver

Release date: April 24, 2024
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8pw6
Q-score: 0.514

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 2 (25 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Heme c (618 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Mus musculus)
Iron/sulfur cluster (351 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Cytochrome b-c1 complex subunit 9 (7 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7b, mitochondrial (9 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7a2, mitochondrial (9 kDa, Protein from Mus musculus)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 8a, mitochondrial (7 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6c (8 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Mus musculus)
Cytochrome b (43 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Sodium ion (22 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Mus musculus)
C respirasome from murine liver (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Protoporphyrin ix containing fe (616 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6a1, mitochondrial (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Copper (ii) ion (63 Da, Ligand)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Dinuclear copper ion (127 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 1 (56 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (19 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Tristearoylglycerol (891 Da, Ligand)
Cytochrome c oxidase subunit 3 (29 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Heme-a (852 Da, Ligand)
Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)

[Show more]

EMD-17991

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A respirasome from murine liver

Release date: April 24, 2024
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8pw7
Q-score: 0.471

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 2 (25 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Heme c (618 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Mus musculus)
Iron/sulfur cluster (351 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Cytochrome b-c1 complex subunit 9 (7 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7b, mitochondrial (9 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7a2, mitochondrial (9 kDa, Protein from Mus musculus)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 8a, mitochondrial (7 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6c (8 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Mus musculus)
Cytochrome b (43 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Sodium ion (22 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Protoporphyrin ix containing fe (616 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6a1, mitochondrial (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Copper (ii) ion (63 Da, Ligand)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Dinuclear copper ion (127 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 1 (56 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (19 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
A respirasome from murine liver (1 MDa, Complex from Mus musculus)
Tristearoylglycerol (891 Da, Ligand)
Cytochrome c oxidase subunit 3 (29 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Heme-a (852 Da, Ligand)
Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)

[Show more]

EMD-19145

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Closed Complex I from murine brain

Release date: April 24, 2024
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8rgp
Q-score: 0.545

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Closed complex i from murine brain (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Flavin mononucleotide (456 Da, Ligand)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Iron/sulfur cluster (351 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)

[Show more]

EMD-19146

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Open Complex I from murine liver

Release date: April 24, 2024
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8rgq
Q-score: 0.515

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Open complex i from murine liver (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Flavin mononucleotide (456 Da, Ligand)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Iron/sulfur cluster (351 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)

[Show more]

EMD-19147

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Closed Complex I from murine liver

Release date: April 24, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8rgr
Q-score: 0.545

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Flavin mononucleotide (456 Da, Ligand)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Closed complex i from murine liver (1 MDa, Complex from Mus musculus)
Iron/sulfur cluster (351 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)

[Show more]

EMD-19148

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Open Complex I from murine brain

Release date: April 24, 2024
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8rgt
Q-score: 0.526

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Flavin mononucleotide (456 Da, Ligand)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Open complex i from murine brain (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Iron/sulfur cluster (351 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)

[Show more]

EMD-18011

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focused map of complex I membrane arm from A respirasome, murine liver

Release date: April 17, 2024
Resolution: 3.3 Å
EM Method: Single-particle

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

A respirasome from murine liver (1 MDa, Complex from Mus musculus)

EMD-18012

Download Map 3D View

focused map of complex I peripheral arm from A respirasome, murine liver

Release date: April 17, 2024
Resolution: 3.1 Å
EM Method: Single-particle

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

A respirasome from murine liver (1 MDa, Complex from Mus musculus)

EMD-18013

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focused map of complex III from A prespirasome, murine liver

Release date: April 17, 2024
Resolution: 3.2 Å
EM Method: Single-particle

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

A respirasome from murine liver (1 MDa, Complex from Mus musculus)

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