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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

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perform basic research in molecular biology

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offer vital services to scientists in the member states

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scientists, students and visitors at all levels

Transfer

and development of technology

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new instruments and methods

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life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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EMD-17989

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CS respirasome from murine liver

Release date: April 24, 2024
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8pw5
Q-score: 0.465

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 2 (25 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Cox7a2l protein (12 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Heme c (618 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Mus musculus)
Iron/sulfur cluster (351 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Cytochrome b-c1 complex subunit 9 (7 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7b, mitochondrial (9 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7a2, mitochondrial (9 kDa, Protein from Mus musculus)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 8a, mitochondrial (7 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6c (8 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Mus musculus)
Cytochrome b (43 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Sodium ion (22 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Protoporphyrin ix containing fe (616 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6a1, mitochondrial (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Copper (ii) ion (63 Da, Ligand)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Dinuclear copper ion (127 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 1 (56 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (19 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Tristearoylglycerol (891 Da, Ligand)
Cytochrome c oxidase subunit 3 (29 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Heme-a (852 Da, Ligand)
Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Mus musculus)
Sc respirasome from murine liver (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)

[Show more]

EMD-17990

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C respirasome from murine liver

Release date: April 24, 2024
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8pw6
Q-score: 0.514

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 2 (25 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Heme c (618 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Mus musculus)
Iron/sulfur cluster (351 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Cytochrome b-c1 complex subunit 9 (7 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7b, mitochondrial (9 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7a2, mitochondrial (9 kDa, Protein from Mus musculus)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 8a, mitochondrial (7 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6c (8 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Mus musculus)
Cytochrome b (43 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Sodium ion (22 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Mus musculus)
C respirasome from murine liver (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Protoporphyrin ix containing fe (616 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6a1, mitochondrial (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Copper (ii) ion (63 Da, Ligand)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Dinuclear copper ion (127 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 1 (56 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (19 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Tristearoylglycerol (891 Da, Ligand)
Cytochrome c oxidase subunit 3 (29 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Heme-a (852 Da, Ligand)
Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)

[Show more]

EMD-17991

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A respirasome from murine liver

Release date: April 24, 2024
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8pw7
Q-score: 0.471

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 2 (25 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Heme c (618 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Mus musculus)
Iron/sulfur cluster (351 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Cytochrome b-c1 complex subunit 9 (7 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7b, mitochondrial (9 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7a2, mitochondrial (9 kDa, Protein from Mus musculus)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 8a, mitochondrial (7 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6c (8 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Mus musculus)
Cytochrome b (43 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Sodium ion (22 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Protoporphyrin ix containing fe (616 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6a1, mitochondrial (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Copper (ii) ion (63 Da, Ligand)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Dinuclear copper ion (127 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 1 (56 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (19 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
A respirasome from murine liver (1 MDa, Complex from Mus musculus)
Tristearoylglycerol (891 Da, Ligand)
Cytochrome c oxidase subunit 3 (29 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Heme-a (852 Da, Ligand)
Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)

[Show more]

EMD-19145

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Closed Complex I from murine brain

Release date: April 24, 2024
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8rgp
Q-score: 0.545

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Closed complex i from murine brain (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Flavin mononucleotide (456 Da, Ligand)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Iron/sulfur cluster (351 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)

[Show more]

EMD-19146

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Open Complex I from murine liver

Release date: April 24, 2024
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8rgq
Q-score: 0.515

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Open complex i from murine liver (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Flavin mononucleotide (456 Da, Ligand)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Iron/sulfur cluster (351 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)

[Show more]

EMD-19147

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Closed Complex I from murine liver

Release date: April 24, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8rgr
Q-score: 0.545

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Flavin mononucleotide (456 Da, Ligand)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Closed complex i from murine liver (1 MDa, Complex from Mus musculus)
Iron/sulfur cluster (351 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)

[Show more]

EMD-19148

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Open Complex I from murine brain

Release date: April 24, 2024
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8rgt
Q-score: 0.526

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) 31 pp. 1061-1071 [ DOI: doi:10.1038/s41594-024-01255-0 Pubmed: 38575788 ]

Sample:

Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Flavin mononucleotide (456 Da, Ligand)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Open complex i from murine brain (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Iron/sulfur cluster (351 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)

[Show more]

EMD-15522

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RCII/PSI complex, class 3

Release date: Aug. 16, 2023
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8am5
Q-score: 0.52

Zhao Z, Vercellino I, Knoppova J, Sobotka R, Murray JW, Nixon PJ, Sazanov LA, Komenda J

Nat Commun (2023) 14 pp. 4681-4681 [ Pubmed: 37542031 DOI: doi:10.1038/s41467-023-40388-6 ]

Sample:

Photosystem ii reaction center protein i (4 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i iron-sulfur center (8 kDa, Protein from Synechocystis sp. PCC 6803)
Beta-carotene (536 Da, Ligand)
Photosystem i reaction center subunit viii (4 kDa, Protein from Synechocystis sp. PCC 6803)
1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
Dodecyl-beta-d-maltoside (510 Da, Ligand)
Photosystem ii protein d1 2 (38 kDa, Protein from Synechocystis sp. PCC 6803)
1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
Photosystem i p700 chlorophyll a apoprotein a2 (81 kDa, Protein from Synechocystis sp. PCC 6803)
Cytochrome b559 subunit alpha (9 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i reaction center subunit ix (4 kDa, Protein from Synechocystis sp. PCC 6803)
Pheophytin a (871 Da, Ligand)
Photosystem ii assembly lipoprotein ycf48 (37 kDa, Protein from Synechocystis sp. PCC 6803)
Fe (ii) ion (55 Da, Ligand)
Photosystem i reaction center subunit ii (15 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i reaction center subunit iii (18 kDa, Protein from Synechocystis sp. PCC 6803)
(1r,2s)-4-{(1e,3e,5e,7e,9e,11e,13e,15e,17e)-18-[(4s)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl}-2,5,5-trimethylcyclohex-3-en-1-ol (568 Da, Ligand)
Protoporphyrin ix containing fe (616 Da, Ligand)
Phylloquinone (450 Da, Ligand)
Photosystem ii d2 protein (37 kDa, Protein from Synechocystis sp. PCC 6803)
Beta,beta-carotene-4,4'-dione (564 Da, Ligand)
Photosystem i reaction center subunit iv (8 kDa, Protein from Synechocystis sp. PCC 6803)
Rcii/psi complex (Complex from Synechocystis sp. PCC 6803)
Cytochrome b559 subunit beta (4 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i reaction center subunit xii (3 kDa, Protein from Synechocystis sp. PCC 6803)
Chlorophyll a (893 Da, Ligand)
(3'r)-3'-hydroxy-beta,beta-caroten-4-one (566 Da, Ligand)
Photosystem i reaction center subunit xi (16 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i p700 chlorophyll a apoprotein a1 (83 kDa, Protein from Synechocystis sp. PCC 6803)
Iron/sulfur cluster (351 Da, Ligand)
Photosystem i reaction center subunit psak 1 (8 kDa, Protein from Synechocystis sp. PCC 6803)
Chlorophyll a isomer (893 Da, Ligand)
Beta,beta-caroten-4-one (550 Da, Ligand)

[Show more]

EMD-15618

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RCII/PSI complex, class 2

Release date: Aug. 16, 2023
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 8asl
Q-score: 0.518

Zhao Z, Vercellino I, Knoppova J, Sobotka R, Murray JW, Nixon PJ, Sazanov LA, Komenda J

Nat Commun (2023) 14 pp. 4681-4681 [ Pubmed: 37542031 DOI: doi:10.1038/s41467-023-40388-6 ]

Sample:

Photosystem ii reaction center protein i (4 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i iron-sulfur center (8 kDa, Protein from Synechocystis sp. PCC 6803)
Beta-carotene (536 Da, Ligand)
Photosystem i reaction center subunit viii (4 kDa, Protein from Synechocystis sp. PCC 6803)
1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
Dodecyl-beta-d-maltoside (510 Da, Ligand)
Photosystem ii protein d1 2 (38 kDa, Protein from Synechocystis sp. PCC 6803)
1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
Photosystem i p700 chlorophyll a apoprotein a2 (81 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i reaction center subunit ix (4 kDa, Protein from Synechocystis sp. PCC 6803)
Cytochrome b559 subunit alpha (9 kDa, Protein from Synechocystis sp. PCC 6803)
Rcii/psi complex class 2 (Complex from Synechocystis sp. PCC 6803)
Pheophytin a (871 Da, Ligand)
Photosystem ii assembly lipoprotein ycf48 (37 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i reaction center subunit ii (15 kDa, Protein from Synechocystis sp. PCC 6803)
Fe (ii) ion (55 Da, Ligand)
Photosystem i reaction center subunit iii (18 kDa, Protein from Synechocystis sp. PCC 6803)
(1r,2s)-4-{(1e,3e,5e,7e,9e,11e,13e,15e,17e)-18-[(4s)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl}-2,5,5-trimethylcyclohex-3-en-1-ol (568 Da, Ligand)
Protoporphyrin ix containing fe (616 Da, Ligand)
Phylloquinone (450 Da, Ligand)
Photosystem ii d2 protein (37 kDa, Protein from Synechocystis sp. PCC 6803)
Beta,beta-carotene-4,4'-dione (564 Da, Ligand)
Photosystem i reaction center subunit iv (8 kDa, Protein from Synechocystis sp. PCC 6803)
Cytochrome b559 subunit beta (4 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i reaction center subunit xii (3 kDa, Protein from Synechocystis sp. PCC 6803)
Chlorophyll a (893 Da, Ligand)
(3'r)-3'-hydroxy-beta,beta-caroten-4-one (566 Da, Ligand)
Photosystem i reaction center subunit xi (16 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i p700 chlorophyll a apoprotein a1 (83 kDa, Protein from Synechocystis sp. PCC 6803)
Iron/sulfur cluster (351 Da, Ligand)
Photosystem i reaction center subunit psak 1 (8 kDa, Protein from Synechocystis sp. PCC 6803)
Chlorophyll a isomer (893 Da, Ligand)
Beta,beta-caroten-4-one (550 Da, Ligand)

[Show more]

EMD-15621

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RCII/PSI complex, focused refinement of PSI

Release date: Aug. 16, 2023
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8asp
Q-score: 0.571

Zhao Z, Vercellino I, Knoppova J, Sobotka R, Murray JW, Nixon PJ, Sazanov LA, Komenda J

Nat Commun (2023) 14 pp. 4681-4681 [ Pubmed: 37542031 DOI: doi:10.1038/s41467-023-40388-6 ]

Sample:

Photosystem i iron-sulfur center (8 kDa, Protein from Synechocystis sp. PCC 6803)
Beta-carotene (536 Da, Ligand)
Photosystem i reaction center subunit viii (4 kDa, Protein from Synechocystis sp. PCC 6803)
1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
Dodecyl-beta-d-maltoside (510 Da, Ligand)
1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
Photosystem i p700 chlorophyll a apoprotein a2 (81 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i reaction center subunit ix (4 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i reaction center subunit ii (15 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i reaction center subunit iii (18 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i reaction center subunit psak 1 (8 kDa, Protein from Synechocystis sp. PCC 6803)
(1r,2s)-4-{(1e,3e,5e,7e,9e,11e,13e,15e,17e)-18-[(4s)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl}-2,5,5-trimethylcyclohex-3-en-1-ol (568 Da, Ligand)
Phylloquinone (450 Da, Ligand)
Beta,beta-carotene-4,4'-dione (564 Da, Ligand)
Photosystem i reaction center subunit iv (8 kDa, Protein from Synechocystis sp. PCC 6803)
Rcii/psi complex (Complex from Synechocystis sp. PCC 6803)
Photosystem i reaction center subunit xii (3 kDa, Protein from Synechocystis sp. PCC 6803)
Chlorophyll a (893 Da, Ligand)
(3'r)-3'-hydroxy-beta,beta-caroten-4-one (566 Da, Ligand)
Photosystem i reaction center subunit xi (16 kDa, Protein from Synechocystis sp. PCC 6803)
Photosystem i p700 chlorophyll a apoprotein a1 (83 kDa, Protein from Synechocystis sp. PCC 6803)
Iron/sulfur cluster (351 Da, Ligand)
Chlorophyll a isomer (893 Da, Ligand)
Beta,beta-caroten-4-one (550 Da, Ligand)

[Show more]

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