Influenza C virus polymerase complex without chicken ANP32A - Subclass 2
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6xzd
Q-score: 0.491
Carrique L, Fan H, Walker AP, Keown JR, Sharps J, Staller E, Barclay WS, Fodor E, Grimes JM
Nature (2020) 587 pp. 638-643 [ Pubmed: 33208942 DOI: doi:10.1038/s41586-020-2927-z ]
- Polymerase acidic protein (82 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
- Influenza c virus polymerase in complex with chicken anp32a (Complex from Influenza C virus (C/Johannesburg/1/66))
- Rna (5'-r(*ap*gp*up*ap*gp*ap*ap*ap*cp*ap*ap*gp*gp*gp*cp*cp*cp*up*gp*c)-3') (14 kDa, RNA from synthetic construct)
- Influenza c virus polymerases (Complex from Influenza C virus (C/Johannesburg/1/66))
- Influenza viral rna (vrna) promoter 47mer (Complex from Synthetic construct)
- Polymerase basic protein 2 (87 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
- Rna-directed rna polymerase catalytic subunit (86 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
Influenza C virus polymerase in complex with chicken ANP32A - Subclass 3
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6xzg
Q-score: 0.365
Carrique L, Fan H, Walker AP, Keown JR, Sharps J, Staller E, Barclay WS, Fodor E, Grimes JM
Nature (2020) 587 pp. 638-643 [ Pubmed: 33208942 DOI: doi:10.1038/s41586-020-2927-z ]
- Polymerase acidic protein (82 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
- Chicken acidic leucine-rich nuclear phosphoprotein 32 family member a (anp32a) (Complex from Gallus gallus)
- Influenza c virus polymerase in complex with chicken anp32a (Complex from Influenza C virus (C/Johannesburg/1/66))
- Polymerase basic protein 2 (104 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
- Influenza viral rna (vrna) promoter 47mer (14 kDa, RNA from Synthetic construct)
- Influenza c virus polymerases (Complex from Influenza C virus (C/Johannesburg/1/66))
- Influenza viral rna (vrna) promoter 47mer (Complex from Synthetic construct)
- Lrrcap domain-containing protein (33 kDa, Protein from Gallus gallus)
- Rna-directed rna polymerase catalytic subunit (86 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
Influenza C virus polymerase in complex with chicken ANP32A - Subclass 4
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6xzp
Q-score: 0.428
Carrique L, Fan H, Walker AP, Keown JR, Sharps J, Staller E, Barclay WS, Fodor E, Grimes JM
Nature (2020) 587 pp. 638-643 [ Pubmed: 33208942 DOI: doi:10.1038/s41586-020-2927-z ]
- Polymerase acidic protein (82 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
- Chicken acidic leucine-rich nuclear phosphoprotein 32 family member a (anp32a) (Complex from Gallus gallus)
- Influenza c virus polymerase in complex with chicken anp32a (Complex from Influenza C virus (C/Johannesburg/1/66))
- Polymerase basic protein 2 (104 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
- Influenza c virus polymerases (Complex from Influenza C virus (C/Johannesburg/1/66))
- Influenza viral rna (vrna) promoter 47mer (Complex from Synthetic construct)
- Rna (5'-r(*ap*gp*up*ap*gp*ap*ap*ap*cp*ap*ap*gp*gp*gp*cp*cp*up*up*up*u)-3') (14 kDa, RNA from Synthetic construct)
- Lrrcap domain-containing protein (33 kDa, Protein from Gallus gallus)
- Rna-directed rna polymerase catalytic subunit (86 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
Influenza C virus polymerase in complex with human ANP32A - Subclass 1
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6xzq
Q-score: 0.4
Carrique L, Fan H, Walker AP, Keown JR, Sharps J, Staller E, Barclay WS, Fodor E, Grimes JM
Nature (2020) 587 pp. 638-643 [ Pubmed: 33208942 DOI: doi:10.1038/s41586-020-2927-z ]
- Polymerase acidic protein (82 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
- Polymerase basic protein 2 (104 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
- Rna (5'-r(*ap*gp*up*ap*gp*ap*ap*ap*cp*ap*ap*gp*gp*gp*cp*cp*cp*up*g)-3') (14 kDa, RNA from synthetic construct)
- Influenza c virus polymerases (Complex from Influenza C virus (C/Johannesburg/1/66))
- Influenza viral rna (vrna) promoter 47mer (Complex from synthetic construct)
- Acidic leucine-rich nuclear phosphoprotein 32 family member a (30 kDa, Protein from Homo sapiens)
- Human acidic leucine-rich nuclear phosphoprotein 32 family member a (anp32a) (Complex from Homo sapiens)
- Influenza c virus polymerase in complex with human anp32a (Complex from Influenza C virus (C/Johannesburg/1/66))
- Rna-directed rna polymerase catalytic subunit (86 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
Influenza C virus polymerase in complex with chicken ANP32A - Subclass 1
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6xzr
Q-score: 0.446
Carrique L, Fan H, Walker AP, Keown JR, Sharps J, Staller E, Barclay WS, Fodor E, Grimes JM
Nature (2020) 587 pp. 638-643 [ Pubmed: 33208942 DOI: doi:10.1038/s41586-020-2927-z ]
- Polymerase acidic protein (82 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
- Chicken acidic leucine-rich nuclear phosphoprotein 32 family member a (anp32a) (Complex from Gallus gallus)
- Influenza c virus polymerase in complex with chicken anp32a (Complex from Influenza C virus (C/Johannesburg/1/66))
- Polymerase basic protein 2 (104 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
- Rna (5'-r(*ap*gp*up*ap*gp*ap*ap*ap*cp*ap*ap*gp*gp*gp*cp*cp*cp*up*g)-3') (14 kDa, RNA from Synthetic construct)
- Influenza c virus polymerases (Complex from Influenza C virus (C/Johannesburg/1/66))
- Influenza viral rna (vrna) promoter 47mer (Complex from Synthetic construct)
- Lrrcap domain-containing protein (33 kDa, Protein from Gallus gallus)
- Rna-directed rna polymerase catalytic subunit (86 kDa, Protein from Influenza C virus (strain C/Johannesburg/1/1966))
Influenza C virus polymerase in complex with human ANP32A - Subclass 2
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6y0c
Q-score: 0.44
Carrique L, Fan H, Walker AP, Keown JR, Sharps J, Staller E, Barclay WS, Fodor E, Grimes JM
Nature (2020) 587 pp. 638-643 [ Pubmed: 33208942 DOI: doi:10.1038/s41586-020-2927-z ]
- Rna-directed rna polymerase catalytic subunit (86 kDa, Protein from Influenza C virus (C/Johannesburg/1/66))
- Influenza viral rna (vrna) promoter 47mer (Complex from Influenza A virus (A/nt/60/1968(H3N2)))
- Polymerase acidic protein (82 kDa, Protein from Influenza C virus (C/Johannesburg/1/66))
- Polymerase basic protein 2 (104 kDa, Protein from Influenza C virus (C/Johannesburg/1/66))
- Influenza c virus polymerase in complex with human anp32a (Complex)
- Influenza c virus polymerases (Complex from Influenza C virus (C/Johannesburg/1/66))
- Rna (5'-r(*ap*gp*up*ap*gp*ap*ap*ap*cp*ap*ap*gp*gp*gp*cp*cp*up*up*up*u)-3') (14 kDa, RNA from Influenza A virus (A/nt/60/1968(H3N2)))
Fan H, Walker AP, Carrique L, Keown JR, Serna Martin I, Karia D, Sharps J, Hengrung N, Pardon E, Steyaert J, Grimes JM, Fodor E
Nature (2019) 573 pp. 287-290 [ DOI: doi:10.1038/s41586-019-1530-7 Pubmed: 31485076 ]
Influenza B virus (B/Panama/45) polymerase Hetermotrimer in complex with 3'5' cRNA promoter
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6qwl
Q-score: 0.355
Fan H, Walker AP, Carrique L, Keown JR, Serna Martin I, Karia D, Sharps J, Hengrung N, Pardon E, Steyaert J, Grimes JM, Fodor E
Nature (2019) 573 pp. 287-290 [ DOI: doi:10.1038/s41586-019-1530-7 Pubmed: 31485076 ]
- Influenza b (panama/45) polymerase hetermotrimer in complex with 3'5' crna promoter (Complex from Influenza B virus (B/Panama/45/1990))
- Influenza b (panama/45) polymerase hetermotrimer in complex with 3'5' crna promoter (250 kDa, Complex)
- 5' crna (4 kDa, RNA from Influenza A virus)
- Polymerase basic protein 2 (89 kDa, Protein from Influenza B virus (strain B/Panama/45/1990))
- 3' crna (4 kDa, RNA from Influenza A virus)
- Rna-directed rna polymerase catalytic subunit (84 kDa, Protein from Influenza B virus (strain B/Panama/45/1990))
- Polymerase acidic protein (83 kDa, Protein from Influenza B virus (strain B/Panama/45/1990))
- Influenza b (panama/45) polymerase hetermotrimer in complex with 3'5' crna promoter (Complex from Influenza A virus)
Resolution: 3.79 Å
EM Method: Single-particle
Fitted PDBs: 6qx3
Q-score: 0.463
Fan H, Walker AP, Carrique L, Keown JR, Serna Martin I, Karia D, Sharps J, Hengrung N, Pardon E, Steyaert J, Grimes JM, Fodor E
Nature (2019) 573 pp. 287-290 [ DOI: doi:10.1038/s41586-019-1530-7 Pubmed: 31485076 ]
- Rna (5'-r(p*up*up*cp*u)-3') (4 kDa, RNA from Influenza A virus (A/nt/60/1968(H3N2)))
- Rna (5'-r(p*ap*gp*cp*ap*ap*ap*ap*gp*cp*a)-3') (4 kDa, RNA from Influenza A virus (A/nt/60/1968(H3N2)))
- Polymerase basic protein 2 (86 kDa, Protein from Influenza A virus (strain A/Northern Territory/60/1968 H3N2))
- Polymerase acidic protein (83 kDa, Protein from Influenza A virus (strain A/Northern Territory/60/1968 H3N2))
- Influenza a virus (a/nt/60/1968) polymerase hetermotrimer in complex with 3'5' crna promoter and nb8205 (250 kDa, Complex from Influenza A virus (A/nt/60/1968(H3N2)))
- Nb8205 (14 kDa, Protein from Lama glama)
- Rna-directed rna polymerase catalytic subunit (86 kDa, Protein from Influenza A virus (strain A/Hong Kong/1/1968 H3N2))
Influenza A virus (A/NT/60/1968) polymerase dimer of heterotrimer in complex with 5' cRNA promoter
Resolution: 4.07 Å
EM Method: Single-particle
Fitted PDBs: 6qx8
Q-score: 0.375
Fan H, Walker AP, Carrique L, Keown JR, Serna Martin I, Karia D, Sharps J, Hengrung N, Pardon E, Steyaert J, Grimes JM, Fodor E
Nature (2019) 573 pp. 287-290 [ DOI: doi:10.1038/s41586-019-1530-7 Pubmed: 31485076 ]
- Influenza a virus (a/nt/60/1968) polymerase dimer of heterotrimer in complex with 5' crna promoter (250 kDa, Complex)
- Rna-directed rna polymerase catalytic subunit (86 kDa, Protein from Influenza A virus (strain A/Northern Territory/60/1968 H3N2))
- Polymerase acidic protein (83 kDa, Protein from Influenza A virus (strain A/Northern Territory/60/1968 H3N2))
- Influenza a virus (a/nt/60/1968) polymerase dimer of heterotrimer in complex with 5' crna promoter (Complex from Influenza A virus (A/nt/60/1968(H3N2)))
- Polymerase basic protein 2 (86 kDa, Protein from Influenza A virus (strain A/Northern Territory/60/1968 H3N2))
- Rna (5'-r(p*ap*gp*cp*ap*ap*ap*ap*gp*cp*ap*gp*a)-3') (4 kDa, RNA from Influenza A virus (A/nt/60/1968(H3N2)))