EDS1-SAG101-NRG1A L134E heterotrimer
Xiao Y, Wu X, Wang Z, Ji K, Zhao Y, Zhang Y, Wan L
Nature (2025) [ DOI: doi:10.1038/s41586-024-08517-3 Pubmed: 39939758 ]
- [[(2~{r},3~{r},4~{r},5~{r})-5-(6-aminopurin-9-yl)-4-[(2~{s},3~{r},4~{s},5~{r})-5-[[[[(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]oxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate (1 kDa, Ligand)
- Eds1-sag101-nrg1a l134e heterotrimer (Complex from Arabidopsis thaliana)
- Senescence-associated carboxylesterase 101 (62 kDa, Protein from Arabidopsis thaliana)
- Probable disease resistance protein at5g66900 (92 kDa, Protein from Arabidopsis thaliana)
- Protein eds1 (71 kDa, Protein from Arabidopsis thaliana)
EDS1-SAG101-NRG1C heterotrimer
Xiao Y, Wu X, Wang Z, Ji K, Zhao Y, Zhang Y, Wan L
Nature (2025) [ DOI: doi:10.1038/s41586-024-08517-3 Pubmed: 39939758 ]
- [[(2~{r},3~{r},4~{r},5~{r})-5-(6-aminopurin-9-yl)-4-[(2~{s},3~{r},4~{s},5~{r})-5-[[[[(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]oxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate (1 kDa, Ligand)
- Senescence-associated carboxylesterase 101 (62 kDa, Protein from Arabidopsis thaliana)
- Probable disease resistance protein at5g66890 (47 kDa, Protein from Arabidopsis thaliana)
- Protein eds1 (71 kDa, Protein from Arabidopsis thaliana)
- Eds1-sag101-nrg1c heterotrimer (Complex from Arabidopsis thaliana)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7mdx
Q-score: 0.363
Sharma S, Zhou R, Wan L, Feng S, Song K, Xu C, Li Y, Liao M
Nat Commun (2021) 12 pp. 4687- [ DOI: doi:10.1038/s41467-021-24965-1 ]
- Lipo-releasing system transmembrane protein lolc (e.c.3.6.3.-), lipoprotein-releasing system transmembrane protein (e.c.3.6.3.-), lipoprotein-releasing system atp-binding protein lold (e.c.7.6.2.-), triacyl-lipoprotein (130 MDa, Complex from Escherichia coli)
- Lipoprotein-releasing system transmembrane protein lole (44 kDa, Protein from Escherichia coli)
- Lipoprotein-releasing system transmembrane protein lolc (42 kDa, Protein from Escherichia coli)
- Pentadecanoic acid (242 Da, Ligand)
- Lipoprotein-releasing system atp-binding protein lold (23 kDa, Protein from Escherichia coli)
- Triacyl-lipoprotein (492 Da, Protein from Escherichia coli)
- (2r)-2-(tridecanoyloxy)propyl hexadecanoate (526 Da, Ligand)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7mdy
Q-score: 0.415
Sharma S, Zhou R, Wan L, Feng S, Song K, Xu C, Li Y, Liao M
Nat Commun (2021) 12 pp. 4687- [ DOI: doi:10.1038/s41467-021-24965-1 ]
- Magnesium ion (24 Da, Ligand)
- Lipoprotein transporter subunit lole (45 kDa, Protein from Escherichia coli)
- Complex of lolc, lole and lold in a 1:1:2 stoichiometry (130 MDa, Complex from Escherichia coli)
- Lipo-releasing system transmembrane protein lolc (43 kDa, Protein from Escherichia coli)
- Lipoprotein-releasing system atp-binding protein lold (25 kDa, Protein from Escherichia coli)
- Adp orthovanadate (544 Da, Ligand)
Cryo_EM map of nucleotide free MlaFEDB complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7cge
Q-score: 0.559
Chi X, Fan Q, Zhang Y, Liang K, Wan L, Zhou Q, Li Y
Cell Res (2020) 30 pp. 1127-1135 [ Pubmed: 32884137 DOI: doi:10.1038/s41422-020-00404-6 ]
- Cryo_em map of nucleotide free mlafedb complex (Complex from Escherichia coli K-12)
- (1r)-2-{[(s)-{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9z)-octadec-9-enoate (749 Da, Ligand)
- Lipid asymmetry maintenance protein mlab (10 kDa, Protein from Escherichia coli (strain K12))
- Lipid asymmetry maintenance abc transporter permease subunit mlae (27 kDa, Protein from Escherichia coli (strain K12))
- Outer membrane lipid asymmetry maintenance protein mlad (19 kDa, Protein from Escherichia coli (strain K12))
- Phospholipid abc transporter atp-binding protein mlaf (29 kDa, Protein from Escherichia coli (strain K12))
Cryo EM map of the MlaFEDB complex in ATP-bound EQtall conformation (Mutation of E170Q on MlaF)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7cgn
Q-score: 0.308
Chi X, Fan Q, Zhang Y, Liang K, Wan L, Zhou Q, Li Y
Cell Res (2020) 30 pp. 1127-1135 [ Pubmed: 32884137 DOI: doi:10.1038/s41422-020-00404-6 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Lipid asymmetry maintenance protein mlab (10 kDa, Protein from Escherichia coli (strain K12))
- Outer membrane lipid asymmetry maintenance protein mlad (19 kDa, Protein from Escherichia coli (strain K12))
- Cryo em map of the mlafedb complex in atp-bound eqtall conformation (mutation of e170q on mlaf) (Complex from Escherichia coli K-12)
- Lipid asymmetry maintenance abc transporter permease subunit mlae (27 kDa, Protein from Escherichia coli (strain K12))
- Phospholipid abc transporter atp-binding protein mlaf (29 kDa, Protein from Escherichia coli (strain K12))
Cryo EM map of the MlaFEDB complex in ATP-bound EQclose conformation (Mutation of E170Q on MlaF)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7ch0
Q-score: 0.487
Chi X, Fan Q, Zhang Y, Liang K, Wan L, Zhou Q, Li Y
Cell Res (2020) 30 pp. 1127-1135 [ Pubmed: 32884137 DOI: doi:10.1038/s41422-020-00404-6 ]
- Cryo em map of the mlafedb complex in atp-bound eqclose conformation (mutation of e170q on mlaf) (Complex from Escherichia coli K-12)
- Lipid asymmetry maintenance abc transporter permease subunit mlae (27 kDa, Protein from Escherichia coli K-12)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Phospholipid abc transporter atp-binding protein mlaf (29 kDa, Protein from Escherichia coli K-12)
- Lipid asymmetry maintenance protein mlab (10 kDa, Protein from Escherichia coli K-12)
- Outer membrane lipid asymmetry maintenance protein mlad (19 kDa, Protein from Escherichia coli K-12)