Focused refinement map of BRR2 region of the human minor pre-B complex
Bai R, Yuan M, Zhang P, Luo T, Shi Y, Wan R
Science (2024) 383 pp. 1245-1252 [ Pubmed: 38484052 DOI: doi:10.1126/science.adn7272 ]
- Human minor pre-b complex (1 MDa, Complex from Homo sapiens)
Focused refinement map of U5 snRNP of the human minor pre-B complex
Bai R, Yuan M, Zhang P, Luo T, Shi Y, Wan R
Science (2024) 383 pp. 1245-1252 [ Pubmed: 38484052 DOI: doi:10.1126/science.adn7272 ]
- Human minor pre-b complex (1 MDa, Complex from Homo sapiens)
Focused refinement map of U5 Sm ring region of the human minor pre-B complex
Bai R, Yuan M, Zhang P, Luo T, Shi Y, Wan R
Science (2024) 383 pp. 1245-1252 [ Pubmed: 38484052 DOI: doi:10.1126/science.adn7272 ]
- Human minor pre-b complex (1 MDa, Complex from Homo sapiens)
Focused refinement map for U4atac/U6atac region of the human minor pre-B complex
Bai R, Yuan M, Zhang P, Luo T, Shi Y, Wan R
Science (2024) 383 pp. 1245-1252 [ Pubmed: 38484052 DOI: doi:10.1126/science.adn7272 ]
- Human minor pre-b complex (1 MDa, Complex from Homo sapiens)
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 8y6o
Q-score: 0.258
Bai R, Yuan M, Zhang P, Luo T, Shi Y, Wan R
Science (2024) 383 pp. 1245-1252 [ Pubmed: 38484052 DOI: doi:10.1126/science.adn7272 ]
- Small nuclear ribonucleoprotein sm d2 (13 kDa, Protein from Homo sapiens)
- U4/u6 small nuclear ribonucleoprotein prp31 (55 kDa, Protein from Homo sapiens)
- U11/u12 small nuclear ribonucleoprotein 35 kda protein (29 kDa, Protein from Homo sapiens)
- U4/u6 small nuclear ribonucleoprotein prp4 (58 kDa, Protein from Homo sapiens)
- Centrosomal at-ac splicing factor (38 kDa, Protein from Homo sapiens)
- Small nuclear ribonucleoprotein e (10 kDa, Protein from Homo sapiens)
- Small nuclear ribonucleoprotein-associated proteins b and b' (24 kDa, Protein from Homo sapiens)
- Nhp2-like protein 1 (14 kDa, Protein from Homo sapiens)
- Human minor pre-b complex (1 MDa, Complex from Homo sapiens)
- Pre-mrna-processing factor 6 (107 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Small nuclear ribonucleoprotein g (8 kDa, Protein from Homo sapiens)
- Small nuclear ribonucleoprotein sm d1 (13 kDa, Protein from Homo sapiens)
- Zinc finger matrin-type protein 5 (20 kDa, Protein from Homo sapiens)
- Small nuclear ribonucleoprotein sm d3 (13 kDa, Protein from Homo sapiens)
- U6atac snrna (40 kDa, RNA from Homo sapiens)
- U11/u12 small nuclear ribonucleoprotein 25 kda protein (15 kDa, Protein from Homo sapiens)
- 116 kda u5 small nuclear ribonucleoprotein component (109 kDa, Protein from Homo sapiens)
- U4/u6 small nuclear ribonucleoprotein prp3 (77 kDa, Protein from Homo sapiens)
- U4/u6.u5 tri-snrnp-associated protein 2 (65 kDa, Protein from Homo sapiens)
- Programmed cell death protein 7 (54 kDa, Protein from Homo sapiens)
- U5 snrna (37 kDa, RNA from Homo sapiens)
- U4atac snrna (42 kDa, RNA from Homo sapiens)
- Pre-mrna (89 kDa, RNA from Homo sapiens)
- U5 small nuclear ribonucleoprotein 40 kda protein (39 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Probable atp-dependent rna helicase ddx23 (95 kDa, Protein from Homo sapiens)
- U4/u6.u5 tri-snrnp-associated protein 1 (90 kDa, Protein from Homo sapiens)
- Pre-mrna-processing-splicing factor 8 (273 kDa, Protein from Homo sapiens)
- Small nuclear ribonucleoprotein f (9 kDa, Protein from Homo sapiens)
- U5 small nuclear ribonucleoprotein 200 kda helicase (244 kDa, Protein from Homo sapiens)
- Serine/threonine-protein kinase prp4 homolog (117 kDa, Protein from Homo sapiens)
- U11/u12 small nuclear ribonucleoprotein 48 kda protein (40 kDa, Protein from Homo sapiens)
- Inositol hexakisphosphate (660 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- U11 snrna (43 kDa, RNA from Homo sapiens)
- Thioredoxin-like protein 4b (17 kDa, Protein from Homo sapiens)
focused refinement map for the U11 snRNP in the human minor pre-B complex
Bai R, Yuan M, Zhang P, Luo T, Shi Y, Wan R
Science (2024) 383 pp. 1245-1252 [ Pubmed: 38484052 DOI: doi:10.1126/science.adn7272 ]
- Human minor pre-b complex (1 MDa, Complex from Homo sapiens)
Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U12 snRNP part
Resolution: 4.66 Å
EM Method: Single-particle
Fitted PDBs: 8y7e
Q-score: 0.004
Bai R, Yuan M, Zhang P, Luo T, Shi Y, Wan R
Science (2024) 383 pp. 1245-1252 [ Pubmed: 38484052 DOI: doi:10.1126/science.adn7272 ]
- Small nuclear ribonucleoprotein sm d2 (13 kDa, Protein from Homo sapiens)
- Human minor pre-b complex (u12 snrnp part) (1 MDa, Complex from Homo sapiens)
- Splicing factor 3b subunit 4 (44 kDa, Protein from Homo sapiens)
- U12 snrna (48 kDa, RNA from Homo sapiens)
- Small nuclear ribonucleoprotein e (10 kDa, Protein from Homo sapiens)
- Splicing factor 3b subunit 3 (135 kDa, Protein from Homo sapiens)
- Small nuclear ribonucleoprotein-associated proteins b and b' (24 kDa, Protein from Homo sapiens)
- Splicing factor 3b subunit 6 (14 kDa, Protein from Homo sapiens)
- Small nuclear ribonucleoprotein g (8 kDa, Protein from Homo sapiens)
- Small nuclear ribonucleoprotein sm d1 (13 kDa, Protein from Homo sapiens)
- Small nuclear ribonucleoprotein sm d3 (13 kDa, Protein from Homo sapiens)
- Splicing factor 3b subunit 5 (10 kDa, Protein from Homo sapiens)
- Sodium channel modifier 1 (25 kDa, Protein from Homo sapiens)
- Splicing factor 3b subunit 1 (146 kDa, Protein from Homo sapiens)
- Pre-mrna (89 kDa, RNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Splicing factor 3b subunit 2 (100 kDa, Protein from Homo sapiens)
- Small nuclear ribonucleoprotein f (9 kDa, Protein from Homo sapiens)
- Phd finger-like domain-containing protein 5a (12 kDa, Protein from Homo sapiens)