Macaca fascicularis NTCP in complex with YN69083 Fab
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 8xcd
Q-score: 0.368
Shionoya K, Park JH, Ekimoto T, Takeuchi JS, Mifune J, Morita T, Ishimoto N, Umezawa H, Yamamoto K, Kobayashi C, Kusunoki A, Nomura N, Iwata S, Muramatsu M, Tame JRH, Ikeguchi M, Park SY, Watashi K
Nat Commun (2024) 15 pp. 9241-9241 [ DOI: doi:10.1038/s41467-024-53533-6 Pubmed: 39455604 ]
- Yn69083 fab heavy chain (27 kDa, Protein from Mus musculus)
- Solute carrier family 10 member a1 (38 kDa, Protein from Macaca fascicularis)
- Taurocholic acid (515 Da, Ligand)
- Macaca fascicularis ntcp in complex with yn69083 fab (89 kDa, Complex from Macaca fascicularis)
- Yn69083 fab light chain (23 kDa, Protein from Mus musculus)
Cryo-EM structure of human NTCP-myr-preS1-YN9048Fab complex
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 8hrx
Q-score: 0.523
Asami J, Park JH, Nomura Y, Kobayashi C, Mifune J, Ishimoto N, Uemura T, Liu K, Sato Y, Zhang Z, Muramatsu M, Wakita T, Drew D, Iwata S, Shimizu T, Watashi K, Park SY, Nomura N, Ohto U
Nat Struct Mol Biol (2024) 31 pp. 447-454 [ Pubmed: 38233573 DOI: doi:10.1038/s41594-023-01191-5 ]
- Ntcp-myr-pres1-yn9048fab (Complex from Homo sapiens)
- Fab heavy chain from antibody igg clone number yn9048 (26 kDa, Protein from Ondatra zibethicus)
- Pres1 protein (fragment) (6 kDa, Protein from Hepatitis B virus)
- Fab light chain from antibody igg clone number yn9048 (23 kDa, Protein from Ondatra zibethicus)
- Sodium/bile acid cotransporter (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of human NTCP-myr-preS1-YN9016Fab complex
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 8hry
Q-score: 0.523
Asami J, Park JH, Nomura Y, Kobayashi C, Mifune J, Ishimoto N, Uemura T, Liu K, Sato Y, Zhang Z, Muramatsu M, Wakita T, Drew D, Iwata S, Shimizu T, Watashi K, Park SY, Nomura N, Ohto U
Nat Struct Mol Biol (2024) 31 pp. 447-454 [ Pubmed: 38233573 DOI: doi:10.1038/s41594-023-01191-5 ]
- Large s protein (fragment) (6 kDa, Protein from Hepatitis B virus)
- Fab light chain from antibody igg clone number yn9016 (23 kDa, Protein from Ondatra zibethicus)
- Fab heavy chain from antibody igg clone number yn9016 (25 kDa, Protein from Ondatra zibethicus)
- Ntcp-myr-pres1-yn9016fab (Complex from Homo sapiens)
- Sodium/bile acid cotransporter (38 kDa, Protein from Homo sapiens)
Human NTCP in complex with YN69083 Fab
Park JH, Iwamoto M, Yun JH, Uchikubo-Kamo T, Son D, Jin Z, Yoshida H, Ohki M, Ishimoto N, Mizutani K, Oshima M, Muramatsu M, Wakita T, Shirouzu M, Liu K, Uemura T, Nomura N, Iwata S, Watashi K, Tame JRH, Nishizawa T, Lee W, Park SY
Nature (2022) 606 pp. 1027-1031 [ DOI: 10.1038/s41586-022-04857-0 Pubmed: 35580630 ]
Image sets:
human NTCP in complex with YN69083 Fab
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7fci
Q-score: 0.497
Park JH, Iwamoto M, Yun JH, Uchikubo-Kamo T, Son D, Jin Z, Yoshida H, Ohki M, Ishimoto N, Mizutani K, Oshima M, Muramatsu M, Wakita T, Shirouzu M, Liu K, Uemura T, Nomura N, Iwata S, Watashi K, Tame JRH, Nishizawa T, Lee W, Park SY
Nature (2022) 606 pp. 1027-1031 [ DOI: doi:10.1038/s41586-022-04857-0 Pubmed: 35580630 ]
- Fab light chain (23 kDa, Protein from Mus musculus)
- Fab heavy chain (27 kDa, Protein from Mus musculus)
- Fab light chain,fab heavy chain (Complex from Mus musculus)
- Sodium/bile acid cotransporter (38 kDa, Protein from Homo sapiens)
- Human ntcp in complex with yn69083 (89 kDa, Cellular component)
- Ntcp (Complex from Homo sapiens)