Structure of the SARS-CoV-2 spike glycoprotein S2 subunit
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 8dya
Q-score: 0.382
Bowen JE, Park YJ, Stewart C, Brown JT, Sharkey WK, Walls AC, Joshi A, Sprouse KR, McCallum M, Tortorici MA, Franko NM, Logue JK, Mazzitelli IG, Nguyen AW, Silva RP, Huang Y, Low JS, Jerak J, Tiles SW, Ahmed K, Shariq A, Dan JM, Zhang Z, Weiskopf D, Sette A, Snell G, Posavad CM, Iqbal NT, Geffner J, Bandera A, Gori A, Sallusto F, Maynard JA, Crotty S, Van Voorhis WC, Simmerling C, Grifantini R, Chu HY, Corti D, Veesler D
Sci Immunol (2022) 7 pp. eadf1421-eadf1421 [ DOI: doi:10.1126/sciimmunol.adf1421 Pubmed: 36356052 ]
- Sars-cov-2 spike s2 subunit (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 spike glycoprotein s2 subunit (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (68 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 6P Mut7 in complex with K398.25 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ Pubmed: 35947674 DOI: doi:10.1126/scitranslmed.abl9605 ]
SARS-CoV-1 in complex with K398.25 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ Pubmed: 35947674 DOI: doi:10.1126/scitranslmed.abl9605 ]
SARS-CoV-2 6P Mut7 in complex with K398.16 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ DOI: doi:10.1126/scitranslmed.abl9605 Pubmed: 35947674 ]
SARS-CoV-2 6P Mut7 in complex with K398.16 Fab (3 bound)
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ Pubmed: 35947674 DOI: doi:10.1126/scitranslmed.abl9605 ]
SARS-CoV-1 in complex with K398.16 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ Pubmed: 35947674 DOI: doi:10.1126/scitranslmed.abl9605 ]
SARS-CoV-2 6P Mut7 in complex with K288.2 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ Pubmed: 35947674 DOI: doi:10.1126/scitranslmed.abl9605 ]
SARS-CoV-2 6P Mut7 in complex with K398.8 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ Pubmed: 35947674 DOI: doi:10.1126/scitranslmed.abl9605 ]
SARS-CoV-2 6P Mut7 in complex with K398.8 Fab (2 bound)
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ Pubmed: 35947674 DOI: doi:10.1126/scitranslmed.abl9605 ]
SARS-CoV-2 6P Mut7 in complex with K398.18 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ Pubmed: 35947674 DOI: doi:10.1126/scitranslmed.abl9605 ]