EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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author:"Wu H" AND xref_links:"pdb" AND author_name:"Gygi SP"

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EMDB [4]

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EMD-40781

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Caspase-1 complex with interleukin-18

Release date: May 8, 2024
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8sv1
Q-score: 0.353

Dong Y, Bonin JP, Devant P, Liang Z, Sever AIM, Mintseris J, Aramini JM, Du G, Gygi SP, Kagan JC, Kay LE, Wu H

Immunity (2024) 57 pp. 1533-1548.e10 [ DOI: doi:10.1016/j.immuni.2024.04.015 Pubmed: 38733997 ]

Sample:

Interleukin-18 (21 kDa, Protein from Homo sapiens)
Caspase-1 (16 kDa, Protein from Homo sapiens)
Protein complex with interleukin (100 MDa, Complex from Homo sapiens)
Caspase-1 (10 kDa, Protein from Homo sapiens)

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EMD-40678

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Caspase-4/Pro-IL-18 complex

Release date: Nov. 22, 2023
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8spb
Q-score: 0.415

Devant P, Dong Y, Mintseris J, Ma W, Gygi SP, Wu H, Kagan JC

Nature (2023) 624 pp. 451-459 [ Pubmed: 37993712 DOI: doi:10.1038/s41586-023-06751-9 ]

Sample:

Caspase-4 subunit p20 (23 kDa, Protein from Homo sapiens)
Caspase-4 subunit p10 (10 kDa, Protein from Homo sapiens)
Caspase-4 in complex with pro-il-18 (144 kDa, Complex from Homo sapiens)
Interleukin-18 (21 kDa, Protein from Homo sapiens)

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EMD-22074

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Cryo-EM structure of NLRP1-DPP9 complex

Release date: March 10, 2021
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6x6a
Q-score: 0.42

Hollingsworth LR, Sharif H, Griswold AR, Fontana P, Mintseris J, Dagbay KB, Paulo JA, Gygi SP, Bachovchin DA, Wu H

Nature (2021) 592 pp. 778-783 [ DOI: doi:10.1038/s41586-021-03350-4 Pubmed: 33731932 ]

Sample:

Nacht, lrr and pyd domains-containing protein 1 (29 kDa, Protein from Homo sapiens)
Nacht, lrr and pyd domains-containing protein 1 (136 kDa, Protein from Homo sapiens)
Dipeptidyl peptidase 9 (98 kDa, Protein from Homo sapiens)
Dpp9-nlrp1 complex (Complex from Homo sapiens)

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EMD-22075

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Cryo-EM structure of NLRP1-DPP9-VbP complex

Release date: March 10, 2021
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6x6c
Q-score: 0.489

Hollingsworth LR, Sharif H, Griswold AR, Fontana P, Mintseris J, Dagbay KB, Paulo JA, Gygi SP, Bachovchin DA, Wu H

Nature (2021) 592 pp. 778-783 [ DOI: doi:10.1038/s41586-021-03350-4 Pubmed: 33731932 ]

Sample:

Nacht, lrr and pyd domains-containing protein 1 (166 kDa, Protein from Homo sapiens)
Dipeptidyl peptidase 9 (101 kDa, Protein from Homo sapiens)
[(2~{r})-1-[(2~{r})-2-azanyl-3-methyl-butanoyl]pyrrolidin-2-yl]boronic acid (214 Da, Ligand)
Dpp9-nlrp1 complex (Complex from Homo sapiens)

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Sort by: Download

Showing 1 - 4 of 4. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [4]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

Preview first 10

Field: