Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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author:"Wu L" AND microscope_name:"FEI TITAN" AND sample_type:"cell"

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EMD-30671

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apo state of class C GPCR

Release date: Sept. 22, 2021
Resolution: 3.96 Å
EM Method: Single-particle
Fitted PDBs: 7dgd
Q-score: 0.232

Zhang J, Qu L, Wu L, Tang X, Luo F, Xu W, Xu Y, Liu ZJ, Hua T

Protein Cell (2021) 12 pp. 662-667 [ DOI: doi:10.1007/s13238-020-00808-5 Pubmed: 33278019 ]

Sample:

Dimer of apo state (Cell from Homo sapiens)
Metabotropic glutamate receptor 1 (93 kDa, Protein from Homo sapiens)

EMD-30672

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intermediate state of class C GPCR

Release date: Sept. 22, 2021
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 7dge
Q-score: 0.388

Zhang J, Qu L, Wu L, Tang X, Luo F, Xu W, Xu Y, Liu ZJ, Hua T

Protein Cell (2021) 12 pp. 662-667 [ DOI: doi:10.1007/s13238-020-00808-5 Pubmed: 33278019 ]

Sample:

Dimer of intermediate state (Cell from Homo sapiens)
Metabotropic glutamate receptor 1 (93 kDa, Protein from Homo sapiens)
(s)-2-amino-3-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl)-propionic acid (189 Da, Ligand)
Nanobody (13 kDa, Protein from Lama glama)

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EMD-30306

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Structural basis for cross-species recognition of COVID-19 virus spike receptor binding domain to bat ACE2

Release date: Jan. 27, 2021
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7c8k
Q-score: 0.482

Liu K, Tan S, Niu S, Wang J, Wu L, Sun H, Zhang Y, Pan X, Qu X, Du P, Meng Y, Jia Y, Chen Q, Deng C, Yan J, Wang HW, Wang Q, Qi J, Gao GF

PNAS (2021) 118 [ Pubmed: 33335073 DOI: doi:10.1073/pnas.2020216118 ]

Sample:

Zinc ion (65 Da, Ligand)
2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Bat ace2 (Cell from Bat AAV SC2991)
Angiotensin-converting enzyme (69 kDa, Protein from Rhinolophus macrotis)

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