Cryo-EM structure of ATP13A2 in the E1-ATP state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8iek
Q-score: 0.377
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Cryo-em structure of atp13a2 in the e1-atp state (Complex from Homo sapiens)
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8iwp
Q-score: 0.346
Wu M, Wu C, Song T, Pan K, Wang Y, Liu Z
Cell Res (2023) 33 pp. 533-545 [ Pubmed: 37258749 DOI: doi:10.1038/s41422-023-00827-x ]
- Calcium ion (40 Da, Ligand)
- Secretory pathway ca(2+)-transporting atpase type 1 (Complex from Homo sapiens)
- Calcium-transporting atpase type 2c member 1 (100 kDa, Protein from Homo sapiens)
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 8iwr
Q-score: 0.39
Wu M, Wu C, Song T, Pan K, Wang Y, Liu Z
Cell Res (2023) 33 pp. 533-545 [ Pubmed: 37258749 DOI: doi:10.1038/s41422-023-00827-x ]
- Calcium ion (40 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Phosphomethylphosphonic acid adenylate ester (505 Da, Ligand)
- Secretory pathway ca(2+)-transporting atpase type 1 (Complex from Homo sapiens)
- Calcium-transporting atpase type 2c member 1 (100 kDa, Protein from Homo sapiens)
Resolution: 3.42 Å
EM Method: Single-particle
Fitted PDBs: 8iws
Q-score: 0.396
Wu M, Wu C, Song T, Pan K, Wang Y, Liu Z
Cell Res (2023) 33 pp. 533-545 [ Pubmed: 37258749 DOI: doi:10.1038/s41422-023-00827-x ]
- Calcium ion (40 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Beryllium trifluoride ion (66 Da, Ligand)
- Secretory pathway ca(2+)-transporting atpase type 1 (Complex from Homo sapiens)
- Calcium-transporting atpase type 2c member 1 (100 kDa, Protein from Homo sapiens)
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8iwt
Q-score: 0.452
Wu M, Wu C, Song T, Pan K, Wang Y, Liu Z
Cell Res (2023) 33 pp. 533-545 [ DOI: doi:10.1038/s41422-023-00827-x Pubmed: 37258749 ]
- Calcium-transporting atpase type 2c member 1 (100 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Secretory pathway ca(2+)-transporting atpase type 1 (Complex from Homo sapiens)
- Beryllium trifluoride ion (66 Da, Ligand)
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 8iwu
Q-score: 0.452
Wu M, Wu C, Song T, Pan K, Wang Y, Liu Z
Cell Res (2023) 33 pp. 533-545 [ Pubmed: 37258749 DOI: doi:10.1038/s41422-023-00827-x ]
- Magnesium ion (24 Da, Ligand)
- Secretory pathway ca(2+)-transporting atpase type 1 (Complex from Homo sapiens)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Calcium-transporting atpase type 2c member 1 (100 kDa, Protein from Homo sapiens)
Resolution: 3.71 Å
EM Method: Single-particle
Fitted PDBs: 8iww
Q-score: 0.34
Wu M, Wu C, Song T, Pan K, Wang Y, Liu Z
Cell Res (2023) 33 pp. 533-545 [ Pubmed: 37258749 DOI: doi:10.1038/s41422-023-00827-x ]
- Calcium ion (40 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Calcium-transporting atpase type 2c member 1 (97 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Secretory pathway ca(2+)-transporting atpase type 1 (Complex from Homo sapiens)
Cryo-EM structure of ATP13A2 in the E1-like state
Resolution: 5.65 Å
EM Method: Single-particle
Fitted PDBs: 8iel
Q-score: 0.229
Cryo-EM structure of ATP13A2 in the E2P state
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8iem
Q-score: 0.262
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Spermine (202 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Beryllium trifluoride ion (66 Da, Ligand)
- Polyamine-transporting atpase 13a2 (123 kDa, Protein from Homo sapiens)
- Polyamine-transporting atpase 13a2 (Complex from Homo sapiens)
Cryo-EM structure of ATP13A2 in the E2-Pi state
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8ien
Q-score: -0.047
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Spermine (202 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Cryo-em structure of atp13a2 in the e2-pi state (Complex from Homo sapiens)